AG Loxton
AG Loxton
Medical Scientist
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A blood RNA signature for tuberculosis disease risk: a prospective cohort study
DE Zak, A Penn-Nicholson, TJ Scriba, E Thompson, S Suliman, LM Amon, ...
The Lancet 387 (10035), 2312-2322, 2016
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
ST Malherbe, S Shenai, K Ronacher, AG Loxton, G Dolganov, M Kriel, ...
Nature medicine 22 (10), 1094-1100, 2016
Four-gene pan-African blood signature predicts progression to tuberculosis
S Suliman, EG Thompson, J Sutherland, J Weiner 3rd, MOC Ota, ...
American journal of respiratory and critical care medicine 197 (9), 1198-1208, 2018
Immunogenicity of Novel DosR Regulon-Encoded Candidate Antigens of Mycobacterium tuberculosis in Three High-Burden Populations in Africa
GF Black, BA Thiel, MO Ota, SK Parida, R Adegbola, WH Boom, ...
Clinical and Vaccine Immunology 16 (8), 1203-1212, 2009
Increased Frequency of Myeloid-derived Suppressor Cells during Active Tuberculosis and after Recent Mycobacterium tuberculosis Infection Suppresses T-Cell …
N Du Plessis, L Loebenberg, M Kriel, F von Groote-Bidlingmaier, ...
American journal of respiratory and critical care medicine 188 (6), 724-732, 2013
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and …
NN Chegou, JS Sutherland, S Malherbe, AC Crampin, PLAM Corstjens, ...
Thorax 71 (9), 785-794, 2016
Host blood RNA signatures predict the outcome of tuberculosis treatment
EG Thompson, Y Du, ST Malherbe, S Shankar, J Braun, J Valvo, ...
Tuberculosis 107, 48-58, 2017
Optimization and Interpretation of Serial QuantiFERON Testing to Measure Acquisition of Mycobacterium tuberculosis Infection
E Nemes, V Rozot, H Geldenhuys, N Bilek, S Mabwe, D Abrahams, ...
American journal of respiratory and critical care medicine 196 (5), 638-648, 2017
Safety and immunogenicity of the recombinant Mycobacterium bovis BCG vaccine VPM1002 in HIV-unexposed newborn infants in South Africa
AG Loxton, JK Knaul, L Grode, A Gutschmidt, C Meller, B Eisele, ...
Clinical and Vaccine Immunology 24 (2), e00439-16, 2017
Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
NN Chegou, GF Black, AG Loxton, K Stanley, PN Essone, MR Klein, ...
BMC infectious diseases 12 (1), 1-14, 2012
Metabolite changes in blood predict the onset of tuberculosis
J Weiner, J Maertzdorf, JS Sutherland, FJ Duffy, E Thompson, S Suliman, ...
Nature communications 9 (1), 1-12, 2018
Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
R Jacobs, S Malherbe, AG Loxton, K Stanley, G Van Der Spuy, G Walzl, ...
Oncotarget 7 (36), 57581, 2016
Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity
JS Sutherland, AG Loxton, MC Haks, D Kassa, L Ambrose, JS Lee, L Ran, ...
Clinical microbiology and infection 20 (4), O230-O238, 2014
Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
NN Chegou, PN Essone, AG Loxton, K Stanley, GF Black, ...
PloS one 7 (6), e38501, 2012
Analysis of Host Responses to Mycobacterium tuberculosis Antigens in a Multi-Site Study of Subjects with Different TB and HIV Infection States in Sub-Saharan Africa
JS Sutherland, MK Lalor, GF Black, LR Ambrose, AG Loxton, NN Chegou, ...
PloS one 8 (9), e74080, 2013
B cells producing type I IFN modulate macrophage polarization in tuberculosis
A Bénard, I Sakwa, P Schierloh, A Colom, I Mercier, L Tailleux, L Jouneau, ...
American journal of respiratory and critical care medicine 197 (6), 801-813, 2018
Differential expression of host biomarkers in saliva and serum samples from individuals with suspected pulmonary tuberculosis
KG Phalane, M Kriel, AG Loxton, A Menezes, K Stanley, GD Van der Spuy, ...
Mediators of inflammation 2013, 2013
Host biomarkers detected in saliva show promise as markers for the diagnosis of pulmonary tuberculosis disease and monitoring of the response to tuberculosis treatment
R Jacobs, E Tshehla, S Malherbe, M Kriel, AG Loxton, K Stanley, ...
Cytokine 81, 50-56, 2016
Epigenetics and proteomics join transcriptomics in the quest for tuberculosis biomarkers
MM Esterhuyse, J Weiner 3rd, E Caron, AG Loxton, M Iannaccone, ...
MBio 6 (5), e01187-15, 2015
Serologic diagnosis of tuberculosis by combining Ig classes against selected mycobacterial targets
R Baumann, S Kaempfer, NN Chegou, W Oehlmann, AG Loxton, ...
Journal of Infection 69 (6), 581-589, 2014
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