| Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ... Nature communications 8 (1), 548, 2017 | 398 | 2017 |
| Molecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle JC Drake, RJ Wilson, Z Yan The FASEB Journal 30 (1), 13, 2016 | 327 | 2016 |
| Assessment of mitochondrial biogenesis and mTORC1 signaling during chronic rapamycin feeding in male and female mice JC Drake, FF Peelor III, LM Biela, MK Watkins, RA Miller, KL Hamilton, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2013 | 110 | 2013 |
| Nrf2 signaling and the slowed aging phenotype: evidence from long-lived models DR Bruns, JC Drake, LM Biela, FF Peelor, BF Miller, KL Hamilton Oxidative medicine and cellular longevity 2015, 2015 | 106 | 2015 |
| Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy JC Drake, RJ Wilson, RC Laker, Y Guan, HR Spaulding, AS Nichenko, ... Proceedings of the National Academy of Sciences 118 (37), e2025932118, 2021 | 95 | 2021 |
| Mitophagy in maintaining skeletal muscle mitochondrial proteostasis and metabolic health with aging. ZY Joshua C. Drake J Physiol, 2017 | 69 | 2017 |
| Calorie restriction does not increase short-term or long-term protein synthesis BF Miller, MM Robinson, DJ Reuland, JC Drake, FF Peelor III, MD Bruss, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2013 | 62 | 2013 |
| Exercise-induced mitophagy in skeletal muscle and heart Y Guan, JC Drake, Z Yan Exercise and sport sciences reviews 47 (3), 151-156, 2019 | 59 | 2019 |
| A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway D Cui, JC Drake, RJ Wilson, RJ Shute, B Lewellen, M Zhang, H Zhao, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 56 | 2020 |
| Long‐lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC 1 activity JC Drake, DR Bruns, FF Peelor III, LM Biela, RA Miller, BF Miller, ... Aging cell 14 (3), 474-482, 2015 | 54 | 2015 |
| The measurement of protein synthesis for assessing proteostasis in studies of slowed aging BF Miller, JC Drake, B Naylor, JC Price, KL Hamilton Ageing research reviews 18, 106-111, 2014 | 53 | 2014 |
| Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy ZY Rebecca J. Wilson, Joshua C. Drake, Di Cui, Mei Zhang, Heather M. Perry ... Mitochondrion, 2017 | 52* | 2017 |
| AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle JC Drake, SE Alway, JM Hollander, DL Williamson American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010 | 52 | 2010 |
| Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation JC Drake, DR Bruns, FF Peelor 3rd, LM Biela, RA Miller, KL Hamilton, ... American Journal of Physiology-Endocrinology and Metabolism 307 (9), E813-E821, 2014 | 45 | 2014 |
| Participation in a 1,000-mile race increases the oxidation of carbohydrate in Alaskan sled dogs BF Miller, JC Drake, FF Peelor III, LM Biela, R Geor, K Hinchcliff, M Davis, ... Journal of Applied Physiology 118 (12), 1502-1509, 2015 | 40 | 2015 |
| Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway AS Keller, L Diederich, C Panknin, LJ DeLalio, JC Drake, R Sherman, ... American Journal of Physiology-Cell Physiology 313 (6), C593-C603, 2017 | 37 | 2017 |
| Exercise-induced mitophagy in skeletal muscle occurs in the absence of stabilization of Pink1 on mitochondria JC Drake, RC Laker, RJ Wilson, M Zhang, Z Yan Cell Cycle 18 (1), 1-6, 2019 | 34 | 2019 |
| Normalizing a hyperactive mTOR initiates muscle growth during obesity DL Williamson, JC Drake Aging (Albany NY) 3 (2), 83, 2011 | 34 | 2011 |
| Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle RJ Wilson, JC Drake, D Cui, BM Lewellen, CC Fisher, M Zhang, ... Free radical biology & medicine 117, 180, 2018 | 25 | 2018 |
| Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat Commun. 2017; 8 (1): 548 RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ... Epub 2017/09/17. PubMed PMID: 28916822, 0 | 23 | |
Zhen YanProfessor and Director, Center for Exercise Medicine Research at Fralin Biomedical ResearchVerified email at vtc.vt.edu
