Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens F Xu, B Nazari, K Moon, LB Bushin, MR Seyedsayamdost Journal of the American Chemical Society 139 (27), 9203-9212, 2017 | 152 | 2017 |
A genetics-free method for high-throughput discovery of cryptic microbial metabolites F Xu, Y Wu, C Zhang, KM Davis, K Moon, LB Bushin, ... Nature chemical biology 15 (2), 161-168, 2019 | 129 | 2019 |
Recent advances in activating silent biosynthetic gene clusters in bacteria D Mao, BK Okada, Y Wu, F Xu, MR Seyedsayamdost Current opinion in microbiology 45, 156-163, 2018 | 111 | 2018 |
Phosphorothioate DNA as an antioxidant in bacteria X Xie, J Liang, T Pu, F Xu, F Yao, Y Yang, YL Zhao, D You, X Zhou, ... Nucleic acids research 40 (18), 9115-9124, 2012 | 90 | 2012 |
A natural product chemist's guide to unlocking silent biosynthetic gene clusters BC Covington, F Xu, MR Seyedsayamdost Annual review of biochemistry 90, 763-788, 2021 | 66 | 2021 |
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor X Qu, N Jiang, F Xu, L Shao, G Tang, B Wilkinson, W Liu Molecular BioSystems 7 (3), 852-861, 2011 | 59 | 2011 |
Bioactivity-HiTES unveils cryptic antibiotics encoded in actinomycete bacteria K Moon, F Xu, C Zhang, MR Seyedsayamdost ACS chemical biology 14 (4), 767-774, 2019 | 55 | 2019 |
Cebulantin, a cryptic lanthipeptide antibiotic uncovered using bioactivity‐coupled HiTES K Moon, F Xu, MR Seyedsayamdost Angewandte Chemie International Edition 58 (18), 5973-5977, 2019 | 50 | 2019 |
Characterization of streptonigrin biosynthesis reveals a cryptic carboxyl methylation and an unusual oxidative cleavage of a N–C bond F Xu, D Kong, X He, Z Zhang, M Han, X Xie, P Wang, H Cheng, M Tao, ... Journal of the American Chemical Society 135 (5), 1739-1748, 2013 | 40 | 2013 |
Identification of (2S,3S)-β-Methyltryptophan as the Real Biosynthetic Intermediate of Antitumor Agent Streptonigrin D Kong, Y Zou, Z Zhang, F Xu, NL Brock, L Zhang, Z Deng, S Lin Scientific Reports 6 (1), 20273, 2016 | 20 | 2016 |
Transformation of streptonigrin to streptonigrone: Flavin reductase-mediated flavin-catalyzed concomitant oxidative decarboxylation of picolinic acid derivatives J Wo, D Kong, NL Brock, F Xu, X Zhou, Z Deng, S Lin ACS Catalysis 6 (5), 2831-2835, 2016 | 15 | 2016 |
Thailandenes, Cryptic Polyene Natural Products Isolated from Burkholderia thailandensis Using Phenotype-Guided Transposon Mutagenesis JD Park, K Moon, C Miller, J Rose, F Xu, CC Ebmeier, JR Jacobsen, ... ACS chemical biology 15 (5), 1195-1203, 2019 | 14 | 2019 |
Sparsomycin biosynthesis highlights unusual module architecture and processing mechanism in non-ribosomal peptide synthetase Z Rui, W Huang, F Xu, M Han, X Liu, S Lin, W Zhang ACS Chemical Biology 10 (8), 1765-1769, 2015 | 14 | 2015 |
Structural and functional analysis of keratinicyclin reveals synergistic antibiosis with vancomycin against Clostridium difficile V Chioti, KL McWhorter, F Xu, PD Jeffrey, K Davis, MR Seyedsayamdost | 2 | 2021 |
Cryptic metabolites and method for activating silent biosynthetic gene clusters in diverse microorganisms MR Seyedsayamdost, F Xu, WU Yihan, L Bushin, K Davis US Patent 11,549,950, 2023 | 1 | 2023 |
Cryptic metabolites and method for activating silent biosynthetic gene clusters in diverse microorganisms MR Seyedsayamdost, F Xu, WU Yihan, L Bushin, K Davis US Patent App. 18/072,800, 2023 | | 2023 |
Cryptic metabolites and method for activating silent biosynthetic gene clusters in actinomycete bacteria MR Seyedsayamdost, F Xu, M Kyuho, B Nazari US Patent 11,629,174, 2023 | | 2023 |
Diastereopure Synthesis of Novel Cyclohexane-Ring-Based Constrained Lanthionine and α-Methyllanthionine through an SN2 Reaction with a β-Bromoalanine as a Key Step J Gracia-Vitoria, Á Carretero, I Osante, C Cativiela Synlett 31 (04), 383-387, 2020 | | 2020 |
Keratinimicins and Keratinicyclins-Novel families of antibacterial and antiviral agents M Seyedsayamdost, F Xu, Y Wu, L Bushin, K Davis | | 2019 |
Exploring Biocatalysts for Stereoselective Synthesis by the Investigation of the Biosynthesis of Natural Products Y Zou, F Xu, D Kong, Q Fang, B Shen, Z Deng, S Lin 한국미생물학회 학술대회논문집, 45-46, 2013 | | 2013 |