Paul Elkington
Paul Elkington
Verified email at soton.ac.uk - Homepage
Title
Cited by
Cited by
Year
Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment
AK Coussens, RJ Wilkinson, Y Hanifa, V Nikolayevskyy, PT Elkington, ...
Proceedings of the National Academy of Sciences 109 (38), 15449-15454, 2012
3432012
The paradox of matrix metalloproteinases in infectious disease
PTG Elkington, CM O'kane, JS Friedland
Clinical & Experimental Immunology 142 (1), 12-20, 2005
3382005
Matrix metalloproteinases in destructive pulmonary pathology
PTG Elkington, JS Friedland
Thorax 61 (3), 259-266, 2006
3352006
Optimisation of bioluminescent reporters for use with mycobacteria
N Andreu, A Zelmer, T Fletcher, PT Elkington, TH Ward, J Ripoll, T Parish, ...
PloS one 5 (5), e10777, 2010
2412010
MMP-1 drives immunopathology in human tuberculosis and transgenic mice
P Elkington, T Shiomi, R Breen, RK Nuttall, CA Ugarte-Gil, NF Walker, ...
The Journal of clinical investigation 121 (5), 1827-1833, 2011
2362011
Tuberculosis, pulmonary cavitation, and matrix metalloproteinases
CWM Ong, PT Elkington, JS Friedland
American journal of respiratory and critical care medicine 190 (1), 9-18, 2014
1742014
Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases
NF Walker, SO Clark, T Oni, N Andreu, L Tezera, S Singh, L Saraiva, ...
American journal of respiratory and critical care medicine 185 (9), 989-997, 2012
1422012
Neutrophil-derived MMP-8 drives AMPK-dependent matrix destruction in human pulmonary tuberculosis
CWM Ong, PT Elkington, S Brilha, C Ugarte-Gil, MT Tome-Esteban, ...
PLoS pathogens 11 (5), e1004917, 2015
1402015
Matrix metalloproteinases in tuberculosis
PT Elkington, CA Ugarte-Gil, JS Friedland
European respiratory journal 38 (2), 456-464, 2011
1382011
Mycobacterium tuberculosis up-regulates matrix metalloproteinase-1 secretion from human airway epithelial cells via a p38 MAPK switch
PTG Elkington, JE Emerson, LDC Lopez-Pascua, CM O’Kane, ...
The Journal of Immunology 175 (8), 5333-5340, 2005
1372005
Mycobacterium tuberculosis, but Not Vaccine BCG, Specifically Upregulates Matrix Metalloproteinase-1
PTG Elkington, RK Nuttall, JJ Boyle, CM O'Kane, DE Horncastle, ...
American journal of respiratory and critical care medicine 172 (12), 1596-1604, 2005
1242005
Towards host-directed therapies for tuberculosis
A Zumla, J Chakaya, M Hoelscher, F Ntoumi, R Rustomjee, C Vilaplana, ...
Nature reviews Drug discovery 14 (8), 511-512, 2015
992015
Tuberculosis immunopathology: the neglected role of extracellular matrix destruction
PT Elkington, JM D’Armiento, JS Friedland
Science translational medicine 3 (71), 71ps6-71ps6, 2011
962011
Hypoxia and tissue destruction in pulmonary TB
M Belton, S Brilha, R Manavaki, F Mauri, K Nijran, YT Hong, NH Patel, ...
Thorax 71 (12), 1145-1153, 2016
932016
Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation
A Kübler, B Luna, C Larsson, NC Ammerman, BB Andrade, M Orandle, ...
The Journal of pathology 235 (3), 431-444, 2015
932015
Synergistic up-regulation of epithelial cell matrix metalloproteinase-9 secretion in tuberculosis
PT Elkington, JA Green, JE Emerson, LD Lopez-Pascua, JJ Boyle, ...
American journal of respiratory cell and molecular biology 37 (4), 431-437, 2007
922007
Controlled generation of microspheres incorporating extracellular matrix fibrils for three‐dimensional cell culture
VL Workman, LB Tezera, PT Elkington, SN Jayasinghe
Advanced functional materials 24 (18), 2648-2657, 2014
912014
The extracellular matrix regulates granuloma necrosis in tuberculosis
B Al Shammari, T Shiomi, L Tezera, MK Bielecka, V Workman, ...
The Journal of infectious diseases 212 (3), 463-473, 2015
902015
Ethnic variation in inflammatory profile in tuberculosis
AK Coussens, RJ Wilkinson, V Nikolayevskyy, PT Elkington, Y Hanifa, ...
PLoS pathogens 9 (7), e1003468, 2013
862013
Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and-3 expression and secretion via NF-κB–and activator protein-1–dependent monocyte networks
JA Green, PT Elkington, CJ Pennington, F Roncaroli, S Dholakia, ...
The Journal of Immunology 184 (11), 6492-6503, 2010
812010
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Articles 1–20