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A Pym
A Pym
Africa Health Research Institute (AHRI)
Verified email at ahri.org - Homepage
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Year
A new evolutionary scenario for the Mycobacterium tuberculosis complex
R Brosch, SV Gordon, M Marmiesse, P Brodin, C Buchrieser, K Eiglmeier, ...
Proceedings of the national academy of Sciences 99 (6), 3684-3689, 2002
21712002
A new evolutionary scenario for the Mycobacterium tuberculosis complex
R Brosch, SV Gordon, M Marmiesse, P Brodin, C Buchrieser, K Eiglmeier, ...
Proceedings of the national academy of Sciences 99 (6), 3684-3689, 2002
21712002
The diarylquinoline TMC207 for multidrug-resistant tuberculosis
AH Diacon, A Pym, M Grobusch, R Patientia, R Rustomjee, L Page-Shipp, ...
New England Journal of Medicine 360 (23), 2397-2405, 2009
9412009
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
AS Pym, P Brodin, R Brosch, M Huerre, ST Cole
Molecular microbiology 46 (3), 709-717, 2002
8942002
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
AS Pym, P Brodin, L Majlessi, R Brosch, C Demangel, A Williams, ...
Nature medicine 9 (5), 533-539, 2003
7922003
Multidrug-resistant tuberculosis and culture conversion with bedaquiline
AH Diacon, A Pym, MP Grobusch, JM de los Rios, E Gotuzzo, I Vasilyeva, ...
New England Journal of Medicine 371 (8), 723-732, 2014
7042014
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis
NAJ Gillespie SH1, Crook AM, McHugh TD, Mendel CM, Meredith SK, Murray SR ...
New England Journal of Medicine 371 (17), 1577-87, 2014
6052014
Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial
G Theron, L Zijenah, D Chanda, P Clowes, A Rachow, M Lesosky, W Bara, ...
The Lancet 383 (9915), 424-435, 2014
4822014
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug …
AH Diacon, PR Donald, A Pym, M Grobusch, RF Patientia, R Mahanyele, ...
Antimicrobial agents and chemotherapy 56 (6), 3271-3276, 2012
4322012
Effect of katG Mutations on the Virulence of Mycobacterium tuberculosis and the Implication for Transmission in Humans
AS Pym, B Saint-Joanis, ST Cole
Infection and immunity 70 (9), 4955-4960, 2002
3422002
Genomic Deletions Classify the Beijing/W Strains as a Distinct Genetic Lineage of Mycobacterium tuberculosis
AG Tsolaki, S Gagneux, AS Pym, YOL Goguet de la Salmoniere, ...
Journal of clinical microbiology 43 (7), 3185-3191, 2005
3112005
Bedaquiline in the treatment of multidrug-and extensively drug-resistant tuberculosis
AS Pym, AH Diacon, SJ Tang, F Conradie, M Danilovits, C Chuchottaworn, ...
European Respiratory Journal 47 (2), 564-574, 2016
2992016
The evolution of mycobacterial pathogenicity: clues from comparative genomics
R Brosch, AS Pym, SV Gordon, ST Cole
Trends in microbiology 9 (9), 452-458, 2001
2952001
Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis
S Gagneux, MV Burgos, K DeRiemer, A Enciso, S Muņoz, PC Hopewell, ...
PLoS pathogens 2 (6), e61, 2006
2812006
Systematic genetic nomenclature for type VII secretion systems
W Bitter, ENG Houben, D Bottai, P Brodin, EJ Brown, JS Cox, ...
PLoS pathogens 5 (10), e1000507, 2009
2732009
Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label …
R Dawson, AH Diacon, D Everitt, C van Niekerk, PR Donald, DA Burger, ...
The Lancet 385 (9979), 1738-1747, 2015
2552015
Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing
CRyPTIC Consortium and the 100,000 Genomes Project
New England Journal of Medicine 379 (15), 1403-1415, 2018
2382018
Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates …
KA Cohen, T Abeel, A Manson McGuire, CA Desjardins, V Munsamy, ...
PLoS medicine 12 (9), e1001880, 2015
2382015
Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
AL Manson, KA Cohen, T Abeel, CA Desjardins, DT Armstrong, CE Barry, ...
Nature genetics 49 (3), 395-402, 2017
2252017
Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study
JM Bryant, SR Harris, J Parkhill, R Dawson, AH Diacon, P van Helden, ...
The Lancet Respiratory Medicine 1 (10), 786-792, 2013
1992013
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