Inflammation and oxidative stress in an obese state and the protective effects of gallic acid PV Dludla, BB Nkambule, B Jack, Z Mkandla, T Mutize, S Silvestri, ... Nutrients 11 (1), 23, 2018 | 229 | 2018 |
A systematic review on the functional role of Th1/Th2 cytokines in type 2 diabetes and related metabolic complications T Mahlangu, PV Dludla, TM Nyambuya, V Mxinwa, SE Mazibuko-Mbeje, ... Cytokine 126, 154892, 2020 | 76 | 2020 |
Aspalathin-enriched green rooibos extract reduces hepatic insulin resistance by modulating PI3K/AKT and AMPK pathways SE Mazibuko-Mbeje, PV Dludla, C Roux, R Johnson, S Ghoor, E Joubert, ... International journal of molecular sciences 20 (3), 633, 2019 | 73 | 2019 |
Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: Updating the status of clinical evidence K Mokgalaboni, Y Ntamo, K Ziqubu, TM Nyambuya, BB Nkambule, ... Food & function 12 (24), 12235-12249, 2021 | 53 | 2021 |
Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications K Ziqubu, PV Dludla, E Joubert, CJF Muller, J Louw, L Tiano, ... Pharmacological Research 158, 104867, 2020 | 51 | 2020 |
Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature N Muvhulawa, PV Dludla, K Ziqubu, SXH Mthembu, F Mthiyane, ... Pharmacological research 178, 106163, 2022 | 48 | 2022 |
N-acetyl cysteine targets hepatic lipid accumulation to curb oxidative stress and inflammation in NAFLD: a comprehensive analysis of the literature PV Dludla, BB Nkambule, SE Mazibuko-Mbeje, TM Nyambuya, ... Antioxidants 9 (12), 1283, 2020 | 48 | 2020 |
The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies PV Dludla, SE Mazibuko-Mbeje, TM Nyambuya, V Mxinwa, L Tiano, ... Pharmacological research 146, 104332, 2019 | 47 | 2019 |
Drug-induced liver injury: clinical evidence of N-acetyl cysteine protective effects Y Ntamo, K Ziqubu, N Chellan, BB Nkambule, TM Nyambuya, ... Oxidative medicine and cellular longevity 2021, 2021 | 45 | 2021 |
Celastrol-induced weight loss is driven by hypophagia and independent from UCP1 K Pfuhlmann, SC Schriever, P Baumann, DG Kabra, L Harrison, ... Diabetes 67 (11), 2456-2465, 2018 | 44 | 2018 |
Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta … PV Dludla, P Orlando, S Silvestri, F Marcheggiani, I Cirilli, TM Nyambuya, ... International journal of molecular sciences 21 (9), 3247, 2020 | 42 | 2020 |
Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials PV Dludla, BB Nkambule, SE Mazibuko-Mbeje, TM Nyambuya, V Mxinwa, ... Pharmacological research 163, 105219, 2021 | 41 | 2021 |
Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration SE Mazibuko-Mbeje, PV Dludla, R Johnson, E Joubert, J Louw, K Ziqubu, ... PloS one 14 (5), e0216172, 2019 | 37 | 2019 |
Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress PV Dludla, SE Mabhida, K Ziqubu, BB Nkambule, SE Mazibuko-Mbeje, ... World journal of diabetes 14 (3), 130, 2023 | 35 | 2023 |
Metformin and heart failure–related outcomes in patients with or without diabetes: A systematic review of randomized controlled trials PV Dludla, TM Nyambuya, R Johnson, S Silvestri, P Orlando, ... Heart Failure Reviews 26, 1437-1445, 2021 | 28 | 2021 |
Exploring the comparative efficacy of metformin and resveratrol in the management of diabetes-associated complications: a systematic review of preclinical studies PV Dludla, S Silvestri, P Orlando, KB Gabuza, SE Mazibuko-Mbeje, ... Nutrients 12 (3), 739, 2020 | 28 | 2020 |
Impact of physical exercise and caloric restriction in patients with type 2 diabetes: Skeletal muscle insulin resistance and mitochondrial dysfunction as ideal therapeutic targets SXH Mthembu, SE Mazibuko-Mbeje, K Ziqubu, TA Nyawo, N Obonye, ... Life Sciences 297, 120467, 2022 | 27 | 2022 |
A polyphenol-enriched fraction of Cyclopia intermedia decreases lipid content in 3T3-L1 adipocytes and reduces body weight gain of obese db/db mice BU Jack, CJ Malherbe, B Huisamen, K Gabuza, S Mazibuko-Mbeje, ... South African journal of botany 110, 216-229, 2017 | 27 | 2017 |
Detrimental effects of lipid peroxidation in type 2 diabetes: Exploring the neutralizing influence of antioxidants SC Shabalala, R Johnson, AK Basson, K Ziqubu, N Hlengwa, ... Antioxidants 11 (10), 2071, 2022 | 26 | 2022 |
Capsaicin, its clinical significance in patients with painful diabetic neuropathy PV Dludla, BB Nkambule, I Cirilli, F Marcheggiani, SE Mabhida, K Ziqubu, ... Biomedicine & Pharmacotherapy 153, 113439, 2022 | 26 | 2022 |