Pharmacology, pharmacokinetics and pharmacodynamics of eculizumab, and possibilities for an individualized approach to eculizumab KL Wijnsma, R Ter Heine, DJAR Moes, S Langemeijer, SEM Schols, ... Clinical Pharmacokinetics 58, 859-874, 2019 | 94 | 2019 |
Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow JMEM Cosemans, SEM Schols, L Stefanini, S De Witt, MAH Feijge, ... Blood, The Journal of the American Society of Hematology 117 (2), 651-660, 2011 | 92 | 2011 |
Spatial distribution of factor Xa, thrombin, and fibrin (ogen) on thrombi at venous shear MA Berny, ICA Munnix, JM Auger, SEM Schols, JMEM Cosemans, ... PloS one 5 (4), e10415, 2010 | 84 | 2010 |
Impaired thrombin generation and fibrin clot formation in patients with dilutional coagulopathy during major surgery SEM Schols, MD Lancé, MAH Feijge, J Damoiseaux, MA Marcus, ... Thrombosis and haemostasis 103 (02), 318-328, 2010 | 80 | 2010 |
Mortality, life expectancy, and causes of death of persons with hemophilia in the Netherlands 2001–2018 S Hassan, RC Monahan, EP Mauser‐Bunschoten, LFD van Vulpen, ... Journal of Thrombosis and Haemostasis 19 (3), 645-653, 2021 | 70 | 2021 |
Hemorrhagic disorders of fibrinolysis: a clinical review JL Saes, SEM Schols, WL Van Heerde, MR Nijziel Journal of Thrombosis and Haemostasis 16 (8), 1498-1509, 2018 | 68 | 2018 |
Increased thrombin generation and fibrinogen level after therapeutic plasma transfusion: relation to bleeding SEM Schols, PEJ van der Meijden, R van Oerle, J Curvers, ... Thrombosis and haemostasis 99 (01), 64-70, 2008 | 68 | 2008 |
Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial MD Lancé, M Ninivaggi, SEM Schols, MAH Feijge, SK Oehrl, G Kuiper, ... Vox Sanguinis 103 (1), 25-34, 2012 | 61 | 2012 |
Effects of plasma dilution on tissue factor–induced thrombin generation and thromboelastography: partly compensating role of platelets SEM Schols, MAH Feijge, MD Lancé, K Hamulyák, H Ten Cate, ... Transfusion 48 (11), 2384-2394, 2008 | 60 | 2008 |
The diagnostic accuracy of bleeding assessment tools for the identification of patients with mild bleeding disorders: a systematic review F Moenen, PJ Nelemans, SEM Schols, HC Schouten, YMC Henskens, ... Haemophilia 24 (4), 525-535, 2018 | 42 | 2018 |
Major differences in clinical presentation, diagnosis and management of men and women with autosomal inherited bleeding disorders F Atiq, JL Saes, MC Punt, KPM van Galen, REG Schutgens, K Meijer, ... EClinicalMedicine 32, 2021 | 37 | 2021 |
Correction of coagulation in dilutional coagulopathy: use of kinetic and capacitive coagulation assays to improve hemostasis SEM Schols, JWM Heemskerk, ECM van Pampus Transfusion Medicine Reviews 24 (1), 44-52, 2010 | 33 | 2010 |
Bleeding severity in patients with rare bleeding disorders: real-life data from the RBiN study JL Saes, MJA Verhagen, K Meijer, MH Cnossen, REG Schutgens, ... Blood advances 4 (20), 5025-5034, 2020 | 30 | 2020 |
Health and treatment outcomes of patients with hemophilia in the Netherlands, 1972–2019 S Hassan, EC van Balen, C Smit, EP Mauser‐Bunschoten, ... Journal of Thrombosis and Haemostasis 19 (10), 2394-2406, 2021 | 26 | 2021 |
Iron handling by the human kidney: Glomerular filtration and tubular reabsorption both contribute to urinary iron excretion SEG van Raaij, AJ Rennings, BJ Biemond, SEM Schols, ETG Wiegerinck, ... American Journal of Physiology-Renal Physiology 316 (3), F606-F614, 2019 | 26 | 2019 |
Successful treatment of a PNH patient non-responsive to eculizumab with the novel complement C5 inhibitor coversin (nomacopan) S Schols, MA Nunn, I Mackie, W Weston-Davies, J Nishimura, Y Kanakura, ... British Journal of Haematology 188 (2), 334-337, 2019 | 25 | 2019 |
Validation of PROMIS Profile‐29 in adults with hemophilia in the Netherlands EC van Balen, L Haverman, S Hassan, EM Taal, C Smit, MH Driessens, ... Journal of Thrombosis and Haemostasis 19 (11), 2687-2701, 2021 | 20 | 2021 |
Pharmacodynamic monitoring of factor VIII replacement therapy in hemophilia A: combining thrombin and plasmin generation LLFG Valke, LH Bukkems, W Barteling, BAP Laros‐van Gorkom, ... Journal of Thrombosis and Haemostasis 18 (12), 3222-3231, 2020 | 20 | 2020 |
Whole exome sequencing in the diagnostic workup of patients with a bleeding diathesis JL Saes, A Simons, SA de Munnik, MR Nijziel, NMA Blijlevens, ... Haemophilia 25 (1), 127-135, 2019 | 18 | 2019 |
Suppressive role of tissue factor pathway inhibitor-α in platelet-dependent fibrin formation under flow is restricted to low procoagulant strength S Thomassen, TG Mastenbroek, F Swieringa, K Winckers, MAH Feijge, ... Thrombosis and haemostasis 118 (03), 502-513, 2018 | 18 | 2018 |