Nanobody-targeted photodynamic therapy selectively kills viral GPCR-expressing glioblastoma cells TWM De Groof, V Mashayekhi, TS Fan, ND Bergkamp, J Sastre Toraño, ... Molecular pharmaceutics 16 (7), 3145-3156, 2019 | 70 | 2019 |
The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth R Heukers, TS Fan, RH de Wit, JR van Senten, TWM De Groof, ... Oncogene 37 (30), 4110-4121, 2018 | 66 | 2018 |
Nanobodies: New avenues for imaging, stabilizing and modulating GPCRs TWM De Groof, V Bobkov, R Heukers, MJ Smit Molecular and cellular endocrinology 484, 15-24, 2019 | 58 | 2019 |
Nanobodies detecting and modulating GPCRs outside in and inside out R Heukers, TWM De Groof, MJ Smit Current Opinion in Cell Biology 57, 115-122, 2019 | 50 | 2019 |
Mechanisms underlying connexin hemichannel activation in disease R Van Campenhout, AR Gomes, TWM De Groof, S Muyldermans, ... International Journal of Molecular Sciences 22 (7), 3503, 2021 | 38 | 2021 |
Antibodies targeting chemokine receptors CXCR4 and ACKR3 V Bobkov, M Arimont, A Zarca, TWM De Groof, B van der Woning, ... Molecular pharmacology 96 (6), 753-764, 2019 | 32 | 2019 |
Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies TWM De Groof, EG Elder, EY Lim, R Heukers, ND Bergkamp, IJ Groves, ... Nature Communications 12 (1), 4436, 2021 | 20 | 2021 |
Selective targeting of ligand-dependent and-independent signaling by GPCR conformation-specific anti-US28 intrabodies TWM De Groof, ND Bergkamp, R Heukers, T Giap, MP Bebelman, ... Nature communications 12 (1), 4357, 2021 | 20 | 2021 |
Therapeutic nanobodies targeting cell plasma membrane transport proteins: A high-risk/high-gain endeavor R Van Campenhout, S Muyldermans, M Vinken, N Devoogdt, ... Biomolecules 11 (1), 63, 2021 | 17 | 2021 |
Emerging applications of nanobodies in cancer therapy RM Awad, F Meeus, H Ceuppens, T Ertveldt, H Hanssens, Q Lecocq, ... International review of cell and molecular biology 369, 143-199, 2022 | 14 | 2022 |
Viral G protein–coupled receptors: Attractive targets for herpesvirus-associated diseases TWM De Groof, EG Elder, M Siderius, R Heukers, JH Sinclair, MJ Smit Pharmacological reviews 73 (2), 828-846, 2021 | 13 | 2021 |
Imaging and therapeutic targeting of the tumor immune microenvironment with biologics S Arnouk, TWM De Groof, JA Van Ginderachter Advanced Drug Delivery Reviews 184, 114239, 2022 | 7 | 2022 |
A few good reasons to use nanobodies for cancer treatment NA Jumapili, M Zivalj, RM Barthelmess, G Raes, TWM De Groof, ... European Journal of Immunology 53 (9), 2250024, 2023 | 4 | 2023 |
Current status and future expectations of nanobodies in oncology trials T De Pauw, L De Mey, JM Debacker, G Raes, JA Van Ginderachter, ... Expert Opinion on Investigational Drugs 32 (8), 705-721, 2023 | 3 | 2023 |
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy CN Funeh, J Bridoux, T Ertveldt, TWM De Groof, DM Chigoho, P Asiabi, ... Pharmaceutics 15 (5), 1378, 2023 | 2 | 2023 |
Generating a novel bispecific nanobody to enhance antitumor activity Q Ge, T Sun, Y Bian, X Xiao, J Zhu Pharmaceutical Fronts 2 (02), e100-e108, 2020 | 2 | 2020 |
Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT K Zeven, TWM De Groof, H Ceuppens, RM Awad, T Ertveldt, W de Mey, ... Frontiers in Immunology 14, 1268900, 2023 | 1 | 2023 |
Identification and Elimination of HCMV-Infected Cells MJ Smit, TWM De Groof, R Heukers, J Sinclair, E Elder US Patent App. 17/632,023, 2022 | 1 | 2022 |
Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for … H Hanssens, F Meeus, Y De Vlaeminck, Q Lecocq, J Puttemans, P Debie, ... Frontiers in Immunology 15, 1389018, 2024 | | 2024 |
The development of Nanobodies against the next-generation immune checkpoint TIGIT with diagnostic and therapeutic potential K Zeven, T De Groof, G Raes, K Breckpot, N Devoogdt BE-PRECISE 2024, 2024 | | 2024 |