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Charles Ng
Charles Ng
Weill Cornell Pathology and Memorial Sloan Kettering Cancer Center
Verified email at mskcc.org
Title
Cited by
Cited by
Year
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)
PI Poulikakos, Y Persaud, M Janakiraman, X Kong, C Ng, G Moriceau, ...
Nature 480 (7377), 387-390, 2011
16292011
Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance
H Shi, G Moriceau, X Kong, MK Lee, H Lee, RC Koya, C Ng, T Chodon, ...
Nature communications 3 (1), 724, 2012
8152012
Focused specificity of intestinal TH17 cells towards commensal bacterial antigens
Y Yang, MB Torchinsky, M Gobert, H Xiong, M Xu, JL Linehan, F Alonzo, ...
Nature 510 (7503), 152-156, 2014
5472014
Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway
M Atefi, E von Euw, N Attar, C Ng, C Chu, D Guo, R Nazarian, ...
PloS one 6 (12), e28973, 2011
2772011
Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma
T Chodon, B Comin-Anduix, B Chmielowski, RC Koya, Z Wu, M Auerbach, ...
Clinical Cancer Research 20 (9), 2457-2465, 2014
2632014
Polymer nanofiber‐embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells
S Hou, L Zhao, Q Shen, J Yu, C Ng, X Kong, D Wu, M Song, X Shi, X Xu, ...
Angewandte Chemie 125 (12), 3463-3467, 2013
2452013
BRAF L597 Mutations in Melanoma Are Associated with Sensitivity to MEK Inhibitors
KB Dahlman, J Xia, K Hutchinson, C Ng, D Hucks, P Jia, M Atefi, Z Su, ...
Cancer discovery 2 (9), 791-797, 2012
2342012
A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition
H Shi, A Hong, X Kong, RC Koya, C Song, G Moriceau, W Hugo, CC Yu, ...
Cancer discovery 4 (1), 69-79, 2014
1832014
Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy
C Ma, AF Cheung, T Chodon, RC Koya, Z Wu, C Ng, E Avramis, ...
Cancer discovery 3 (4), 418-429, 2013
1492013
Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations
F Niehr, E von Euw, N Attar, D Guo, D Matsunaga, H Sazegar, C Ng, ...
Journal of translational medicine 9, 1-13, 2011
1142011
Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines
E von Euw, M Atefi, N Attar, C Chu, S Zachariah, BL Burgess, S Mok, C Ng, ...
Molecular cancer 11, 1-9, 2012
902012
Niche-selective inhibition of pathogenic Th17 cells by targeting metabolic redundancy
L Wu, KER Hollinshead, Y Hao, C Au, L Kroehling, C Ng, WY Lin, D Li, ...
Cell 182 (3), 641-654. e20, 2020
852020
Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma
M Atefi, B Titz, E Avramis, C Ng, DJL Wong, A Lassen, M Cerniglia, ...
Molecular cancer 14, 1-12, 2015
642015
COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors
H Escuin-Ordinas, M Atefi, Y Fu, A Cass, C Ng, RR Huang, S Yashar, ...
Molecular oncology 8 (2), 250-260, 2014
532014
Heritable gene regulation in the CD4: CD8 T cell lineage choice
PDA Issuree, CP Ng, DR Littman
Frontiers in immunology 8, 250073, 2017
392017
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
W Gu, H Wang, X Huang, J Kraiczy, PNP Singh, C Ng, S Dagdeviren, ...
Cell Stem Cell 29 (1), 101-115. e10, 2022
372022
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes
T Sano, T Kageyama, V Fang, R Kedmi, CS Martinez, J Talbot, A Chen, ...
Cell reports 36 (8), 2021
272021
The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells
C Ng, M Aichinger, T Nguyen, C Au, T Najar, L Wu, KR Mesa, W Liao, ...
Genes & Development 33 (11-12), 669-683, 2019
272019
Lactate activates the mitochondrial electron transport chain independently of its metabolism
X Cai, CP Ng, O Jones, TS Fung, KW Ryu, D Li, CB Thompson
Molecular cell 83 (21), 3904-3920. e7, 2023
222023
Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell–derived cytokines
S Schwörer, FV Cimino, M Ros, KM Tsanov, C Ng, SW Lowe, ...
Cancer research 83 (10), 1596-1610, 2023
202023
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