Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian, M Zacher, ... Nature genetics 50 (8), 1112-1121, 2018 | 2069 | 2018 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 592 | 2019 |
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study AF Schmidt, DI Swerdlow, MV Holmes, RS Patel, Z Fairhurst-Hunter, ... The lancet Diabetes & endocrinology 5 (2), 97-105, 2017 | 381 | 2017 |
Multivariate genome-wide analyses of the well-being spectrum BML Baselmans, R Jansen, HF Ip, J van Dongen, A Abdellaoui, ... Nature genetics 51 (3), 445-451, 2019 | 259 | 2019 |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... Nature genetics 53 (9), 1311-1321, 2021 | 221 | 2021 |
Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring S Finer, C Mathews, R Lowe, M Smart, S Hillman, L Foo, A Sinha, ... Human molecular genetics 24 (11), 3021-3029, 2015 | 209 | 2015 |
Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits E Hannon, TJ Gorrie-Stone, MC Smart, J Burrage, A Hughes, Y Bao, ... The American Journal of Human Genetics 103 (5), 654-665, 2018 | 147 | 2018 |
ANGPTL4 E40K and T266M: Effects on Plasma Triglyceride and HDL Levels, Postprandial Responses, and CHD Risk PJ Talmud, M Smart, E Presswood, JA Cooper, V Nicaud, F Drenos, ... Arteriosclerosis, thrombosis, and vascular biology 28 (12), 2319-2325, 2008 | 123 | 2008 |
Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes A Adaikalakoteswari, S Finer, PD Voyias, CM McCarthy, M Vatish, ... Clinical epigenetics 7, 1-14, 2015 | 117 | 2015 |
BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours V D’Arcy, N Pore, F Docquier, ZK Abdullaev, I Chernukhin, G-X Kita, S Rai, M ... British Journal Cancer 98, 571-579, 2008 | 115 | 2008 |
Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations BP Prins, KB Kuchenbaecker, Y Bao, M Smart, D Zabaneh, G Fatemifar, ... Scientific reports 7 (1), 11008, 2017 | 101 | 2017 |
Associations of autozygosity with a broad range of human phenotypes DW Clark, Y Okada, KHS Moore, D Mason, N Pirastu, I Gandin, ... Nature communications 10 (1), 4957, 2019 | 92 | 2019 |
Systematic underestimation of the epigenetic clock and age acceleration in older subjects LY El Khoury, T Gorrie-Stone, M Smart, A Hughes, Y Bao, A Andrayas, ... Genome biology 20, 1-10, 2019 | 90 | 2019 |
The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk MC Smart-Halajko, MR Robciuc, JA Cooper, M Jauhiainen, M Kumari, ... Arteriosclerosis, thrombosis, and vascular biology 30 (11), 2277-2282, 2010 | 84 | 2010 |
Socioeconomic position and DNA methylation age acceleration across the life course A Hughes, M Smart, T Gorrie-Stone, E Hannon, J Mill, Y Bao, J Burrage, ... American journal of epidemiology 187 (11), 2346-2354, 2018 | 83 | 2018 |
Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates SL Hillman, S Finer, MC Smart, C Mathews, R Lowe, VK Rakyan, ... Epigenetics 10 (1), 50-61, 2015 | 80 | 2015 |
Is famine exposure during developmental life in rural Bangladesh associated with a metabolic and epigenetic signature in young adulthood? A historical cohort study S Finer, MS Iqbal, R Lowe, BW Ogunkolade, S Pervin, C Mathews, ... BMJ open 6 (11), e011768, 2016 | 79 | 2016 |
COGENT (Cognitive Genomics Consortium); Social Science Genetic Association Consortium. Gene discovery and polygenic prediction from a genome-wide association study of … JJ Lee, R Wedow, A Okbay, 23andMe Research Team Nat Genet 50 (8), 1112-1121, 2018 | 71 | 2018 |
Vitamin D and cognitive function: A Mendelian randomisation study J Maddock, A Zhou, A Cavadino, E Kuźma, Y Bao, MC Smart, KU Saum, ... Scientific reports 7 (1), 13230, 2017 | 69 | 2017 |
The potential of BORIS detected in the leukocytes of breast cancer patients as an early marker of tumorigenesis V D'Arcy, ZK Abdullaev, N Pore, F Docquier, V Torrano, I Chernukhin, ... Clinical cancer research 12 (20), 5978-5986, 2006 | 61 | 2006 |