A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ... Science 316 (5826), 889-894, 2007 | 5579 | 2007 |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ... Science 316 (5829), 1336-1341, 2007 | 2562 | 2007 |
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, ... Nature genetics 40 (5), 638-645, 2008 | 2271 | 2008 |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ... Nature genetics 42 (7), 579-589, 2010 | 2161 | 2010 |
Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1565 | 2008 |
Genome-wide association study identifies eight loci associated with blood pressure C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, ... Nature genetics 41 (6), 666-676, 2009 | 1427 | 2009 |
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1424 | 2007 |
The Lin28/let-7 axis regulates glucose metabolism H Zhu, N Shyh-Chang, AV Segrè, G Shinoda, SP Shah, WS Einhorn, ... Cell 147 (1), 81-94, 2011 | 974 | 2011 |
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance AK Manning, MF Hivert, RA Scott, JL Grimsby, N Bouatia-Naji, H Chen, ... Nature genetics 44 (6), 659-669, 2012 | 898 | 2012 |
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians YS Cho, CH Chen, C Hu, J Long, RT Hee Ong, X Sim, F Takeuchi, Y Wu, ... Nature genetics 44 (1), 67-72, 2012 | 707 | 2012 |
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ... Nature 450 (7171), 887-892, 2007 | 701 | 2007 |
Parental origin of sequence variants associated with complex diseases A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ... Nature 462 (7275), 868-874, 2009 | 656 | 2009 |
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma JC Chambers, W Zhang, J Sehmi, X Li, MN Wass, P Van der Harst, ... Nature genetics 43 (11), 1131-1138, 2011 | 614 | 2011 |
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ... PLoS genetics 8 (3), e1002607, 2012 | 555 | 2012 |
A common variant of HMGA2 is associated with adult and childhood height in the general population MN Weedon, G Lettre, RM Freathy, CM Lindgren, BF Voight, JRB Perry, ... Nature genetics 39 (10), 1245-1250, 2007 | 483 | 2007 |
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ... Diabetes 60 (10), 2624-2634, 2011 | 451 | 2011 |
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study arcOGEN Consortium, arcOGEN Collaborators The Lancet 380 (9844), 815-823, 2012 | 444 | 2012 |
Genetic variation in selenoprotein S influences inflammatory response JE Curran, JBM Jowett, KS Elliott, Y Gao, K Gluschenko, J Wang, ... Nature genetics 37 (11), 1234-1241, 2005 | 431 | 2005 |
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study RA Evans, OC Leavy, M Richardson, O Elneima, HJC McAuley, ... The Lancet Respiratory Medicine 10 (8), 761-775, 2022 | 286 | 2022 |
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes MCY Ng, D Shriner, BH Chen, J Li, WM Chen, X Guo, J Liu, SJ Bielinski, ... PLoS genetics 10 (8), e1004517, 2014 | 241 | 2014 |