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Cory Sago
Cory Sago
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High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ...
Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018
2392018
A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation
K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ...
Nano letters 18 (3), 2148-2157, 2018
1662018
Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses
K Paunovska, AJ Da Silva Sanchez, CD Sago, Z Gan, MP Lokugamage, ...
Advanced materials 31 (14), 1807748, 2019
1422019
Constrained nanoparticles deliver siRNA and sgRNA to T cells in vivo without targeting ligands
MP Lokugamage, CD Sago, Z Gan, BR Krupczak, JE Dahlman
Advanced Materials 31 (41), 1902251, 2019
1112019
Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery
K Paunovska, CJ Gil, MP Lokugamage, CD Sago, M Sato, GN Lando, ...
ACS nano 12 (8), 8341-8349, 2018
1092018
Nanoparticles that deliver RNA to bone marrow identified by in vivo directed evolution
CD Sago, MP Lokugamage, FZ Islam, BR Krupczak, M Sato, JE Dahlman
Journal of the American Chemical Society 140 (49), 17095-17105, 2018
952018
Mild innate immune activation overrides efficient nanoparticle‐mediated RNA delivery
MP Lokugamage, Z Gan, C Zurla, J Levin, FZ Islam, S Kalathoor, M Sato, ...
Advanced materials 32 (1), 1904905, 2020
882020
Testing thousands of nanoparticles in vivo using DNA barcodes
MP Lokugamage, CD Sago, JE Dahlman
Current Opinion in Biomedical Engineering 7, 1-8, 2018
672018
Using large datasets to understand nanotechnology
K Paunovska, D Loughrey, CD Sago, R Langer, JE Dahlman
Advanced Materials 31 (43), 1902798, 2019
572019
Modifying a commonly expressed endocytic receptor retargets nanoparticles in vivo
CD Sago, MP Lokugamage, GN Lando, N Djeddar, NN Shah, C Syed, ...
Nano letters 18 (12), 7590-7600, 2018
422018
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver
CD Sago, MP Lokugamage, D Loughrey, KE Lindsay, R Hincapie, ...
Nature biomedical engineering 6 (2), 157-167, 2022
372022
Cell subtypes within the liver microenvironment differentially interact with lipid nanoparticles
CD Sago, BR Krupczak, MP Lokugamage, Z Gan, JE Dahlman
Cellular and Molecular Bioengineering 12, 389-397, 2019
362019
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo
SG Huayamares, MP Lokugamage, R Rab, AJDS Sanchez, H Kim, ...
Journal of Controlled Release 357, 394-403, 2023
212023
Barcoding chemical modifications into nucleic acids improves drug stability in vivo
CD Sago, S Kalathoor, JP Fitzgerald, GN Lando, N Djeddar, AV Bryksin, ...
Journal of materials chemistry B 6 (44), 7197-7203, 2018
192018
Screening of chemically distinct lipid nanoparticles in vivo using DNA barcoding technology towards effectively delivering messenger RNA to hematopoietic stem and progenitor cells
C Sago, E Campbell, B Lutz, N Patwardhan, G Hamilton, C Wong, D Lee, ...
Blood 138, 2931, 2021
42021
Nanomaterials
GL Hamilton, NN Patwardhan, CD Sago, MFG Shehata, MB Chhabra
US Patent App. 17/142,595, 2021
12021
Multiplexed Analysis of Materials for Tissue Delivery
J Dahlman, S Cory, M Lokugamage
US Patent App. 16/753,241, 2020
12020
Nanomaterials comprising an ionizable lipid
GL Hamilton, MF Shehata, CD Sago, NN Patwardhan, MB Chhabra
US Patent App. 18/220,867, 2024
2024
Nanomaterials comprising carbonates
GL Hamilton, NN Patwardhan, CD Sago, MF Shehata, MB Chhabra
US Patent App. 18/211,840, 2023
2023
Ionizable lipids for nanomaterials
MF Shehata, GL Hamilton, NN Patwardhan, CD Sago, MB Chhabra
US Patent App. 18/220,874, 2023
2023
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Articles 1–20