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Alejandro J. Da Silva Sanchez
Alejandro J. Da Silva Sanchez
Nava Therapeutics
Verified email at navatx.com
Title
Cited by
Cited by
Year
Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses
K Paunovska, AJ Da Silva Sanchez, CD Sago, Z Gan, MP Lokugamage, ...
Advanced materials 31 (14), 1807748, 2019
1432019
Treating cystic fibrosis with mRNA and CRISPR
A Da Silva Sanchez, K Paunovska, A Cristian, JE Dahlman
Human gene therapy 31 (17-18), 940-955, 2020
512020
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery
C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ...
Nature Nanotechnology 17 (8), 871-879, 2022
402022
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo
A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ...
Nano letters 23 (3), 993-1002, 2023
232023
Universal Barcoding Predicts In Vivo ApoE-Independent Lipid Nanoparticle Delivery
AJ Da Silva Sanchez, C Dobrowolski, A Cristian, ES Echeverri, K Zhao, ...
Nano Letters 22 (12), 4822-4830, 2022
232022
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery
MZC Hatit, CN Dobrowolski, MP Lokugamage, D Loughrey, H Ni, C Zurla, ...
Nature Chemistry 15 (4), 508-515, 2023
222023
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo
SG Huayamares, MP Lokugamage, R Rab, AJDS Sanchez, H Kim, ...
Journal of Controlled Release 357, 394-403, 2023
212023
Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery
AJDS Sanchez, K Zhao, SG Huayamares, MZC Hatit, MP Lokugamage, ...
Journal of Controlled Release 353, 270-277, 2023
202023
Increased PIP3 activity blocks nanoparticle mRNA delivery
K Paunovska, A Da Silva Sanchez, MT Foster, D Loughrey, EL Blanchard, ...
Science advances 6 (30), eaba5672, 2020
192020
The extent to which lipid nanoparticles require apolipoprotein E and low-density lipoprotein receptor for delivery changes with ionizable lipid structure
K Paunovska, AJ Da Silva Sanchez, MP Lokugamage, D Loughrey, ...
Nano Letters 22 (24), 10025-10033, 2022
122022
A systematic analysis of biotech startups that went public in the first half of 2021
SG Huayamares, MP Lokugamage, AJDS Sanchez, JE Dahlman
Current Research in Biotechnology 4, 392-401, 2022
92022
Substituting Poly (Ethylene Glycol) Lipids with Poly (2‐Ethyl‐2‐Oxazoline) Lipids Improves Lipid Nanoparticle Repeat Dosing
AJDS Sanchez, D Loughrey, ES Echeverri, SG Huayamares, A Radmand, ...
Advanced Healthcare Materials, 2304033, 2024
12024
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