Leonard C Harrison
Leonard C Harrison
Professor of Medicine
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Pro-inflammatory CD11c+ CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity
JM Wentworth, G Naselli, WA Brown, L Doyle, B Phipson, GK Smyth, ...
Diabetes 59 (7), 1648-1656, 2010
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
E Mariņo, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ...
Nature immunology 18 (5), 552-562, 2017
Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes.
MC Honeyman, BS Coulson, NL Stone, SA Gellert, PN Goldwater, ...
Diabetes 49 (8), 1319-1324, 2000
Latent autoimmune diabetes in adults (LADA) should be less latent
S Fourlanos, F Dotta, CJ Greenbaum, JP Palmer, O Rolandsson, ...
Diabetologia 48, 2206-2212, 2005
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.
IL Campbell, TW Kay, L Oxbrow, LC Harrison
The Journal of clinical investigation 87 (2), 739-742, 1991
Aerosol insulin induces regulatory CD8 γδ T cells that prevent murine insulin-dependent diabetes
LC Harrison, M Dempsey-Collier, DR Kramer, K Takahashi
The Journal of experimental medicine 184 (6), 2167-2174, 1996
Antigen-induced regulatory T cells in autoimmunity
MG von Herrath, LC Harrison
Nature Reviews Immunology 3 (3), 223-232, 2003
Prediction of MHC class II-binding peptides using an evolutionary algorithm and artificial neural network.
V Brusic, G Rudy, G Honeyman, J Hammer, L Harrison
Bioinformatics (Oxford, England) 14 (2), 121-130, 1998
Diurnal rhythms of pro-inflammatory cytokines: regulation by plasma cortisol and therapeutic implications
N Petrovsky, P McNair, LC Harrison
Cytokine 10 (4), 307-312, 1998
Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele
G Morahan, D Huang, SI Ymer, MR Cancilla, K Stephen, P Dabadghao, ...
Nature genetics 27 (2), 218-221, 2001
Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice
MB French, J Allison, DS Cram, HE Thomas, M Dempsey-Collier, A Silva, ...
Diabetes 46 (1), 34-39, 1997
Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
LC Harrison, MC Honeyman, HJ DeAizpurua, RS Schmidli, PG Colman, ...
The Lancet 341 (8857), 1365-1369, 1993
Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells
J Allison, IL Campbell, G Morahan, TE Mandel, LC Harrison, J Miller
Nature 333 (6173), 529-533, 1988
T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents
MC Honeyman, NL Stone, LC Harrison
Molecular medicine 4, 231-239, 1998
Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status
D Mittag, AI Proietto, T Loudovaris, SI Mannering, D Vremec, K Shortman, ...
The Journal of Immunology 186 (11), 6207-6217, 2011
The chronobiology of human cytokine production
N Petrovsky, LC Harrison
Cytokines and Cytokine Receptors, 810-824, 2001
MHCPEP, a database of MHC-binding peptides: update 1997
V Brusic, G Rudy, LC Harrison
Nucleic acids research 26 (1), 368-371, 1998
IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans.
IL Campbell, A Iscaro, LC Harrison
Journal of immunology (Baltimore, Md.: 1950) 141 (7), 2325-2329, 1988
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
B Krishnamurthy, NL Dudek, MD McKenzie, AW Purcell, AG Brooks, ...
The Journal of clinical investigation 116 (12), 3258-3265, 2006
Insulin resistance is a risk factor for progression to type 1 diabetes
S Fourlanos, P Narendran, GB Byrnes, PG Colman, LC Harrison
Diabetologia 47, 1661-1667, 2004
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