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Alex Sparreboom
Alex Sparreboom
Professor and Lucius A. Wing Chair, The Ohio State University
Verified email at osu.edu - Homepage
Title
Cited by
Cited by
Year
Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation
H Gelderblom, J Verweij, K Nooter, A Sparreboom
European journal of cancer 37 (13), 1590-1598, 2001
21152001
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
A Sparreboom, J Van Asperen, U Mayer, AH Schinkel, JW Smit, ...
Proceedings of the National Academy of Sciences 94 (5), 2031-2035, 1997
11191997
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11)
RHJ Mathijssen, RJ van Alphen, J Verweij, WJ Loos, K Nooter, G Stoter, ...
Clinical cancer research 7 (8), 2182-2194, 2001
9232001
Pharmacological effects of formulation vehicles: implications for cancer chemotherapy
AJ Ten Tije, J Verweij, WJ Loos, A Sparreboom
Clinical pharmacokinetics 42, 665-685, 2003
8012003
Herbal remedies in the United States: potential adverse interactions with anticancer agents
A Sparreboom, MC Cox, MR Acharya, WD Figg
Journal of clinical oncology 22 (12), 2489-2503, 2004
6362004
Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline
JJ Griggs, PB Mangu, S Temin, GH Lyman
Journal of oncology practice 8 (4), e59, 2012
5892012
Effects of St. John's wort on irinotecan metabolism
RHJ Mathijssen, J Verweij, P De Bruijn, WJ Loos, A Sparreboom
Journal of the National Cancer Institute 94 (16), 1247-1249, 2002
5812002
Comparative preclinical and clinical pharmacokinetics of a cremophor-free, nanoparticle albumin-bound paclitaxel (ABI-007) and paclitaxel formulated in Cremophor (Taxol)
A Sparreboom, CD Scripture, V Trieu, PJ Williams, T De, A Yang, B Beals, ...
Clinical cancer research 11 (11), 4136-4143, 2005
5752005
Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma
QC Ryan, D Headlee, M Acharya, A Sparreboom, JB Trepel, J Ye, ...
Journal of Clinical Oncology 23 (17), 3912-3922, 2005
4892005
Contribution of organic cation transporter 2 (OCT2) to cisplatin‐induced nephrotoxicity
KK Filipski, RH Mathijssen, TS Mikkelsen, AH Schinkel, A Sparreboom
Clinical Pharmacology & Therapeutics 86 (4), 396-402, 2009
4642009
Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications
A Sparreboom, L Van Zuylen, E Brouwer, WJ Loos, P De Bruijn, ...
Cancer research 59 (7), 1454-1457, 1999
4341999
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
LR Treviņo, N Shimasaki, W Yang, JC Panetta, C Cheng, D Pei, D Chan, ...
Journal of Clinical Oncology 27 (35), 5972, 2009
3882009
Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL
A Sparreboom, O van Tellingen, WJ Nooijen, JH Beijnen
Cancer research 56 (9), 2112-2115, 1996
3871996
Role of formulation vehicles in taxane pharmacology
L Van Zuylen, J Verweij, A Sparreboom
Investigational new drugs 19, 125-141, 2001
3792001
Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias
I Gojo, A Jiemjit, JB Trepel, A Sparreboom, WD Figg, S Rollins, ML Tidwell, ...
Blood 109 (7), 2781-2790, 2007
3642007
Peripheral neuropathy induced by paclitaxel: recent insights and future perspectives
CD Scripture, WD Figg, A Sparreboom
Current neuropharmacology 4 (2), 165-172, 2006
3462006
Irinotecan pathway genotype analysis to predict pharmacokinetics
RHJ Mathijssen, S Marsh, MO Karlsson, R Xie, SD Baker, J Verweij, ...
Clinical cancer research 9 (9), 3246-3253, 2003
3242003
Role of body surface area in dosing of investigational anticancer agents in adults, 1991–2001
SD Baker, J Verweij, EK Rowinsky, RC Donehower, JHM Schellens, ...
Journal of the National Cancer Institute 94 (24), 1883-1888, 2002
3212002
Pharmacogenomics of ABC transporters and its role in cancer chemotherapy
A Sparreboom, R Danesi, Y Ando, J Chan, WD Figg
Drug Resistance Updates 6 (2), 71-84, 2003
3062003
Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype
A Sparreboom, H Gelderblom, S Marsh, R Ahluwalia, R Obach, P Principe, ...
Clinical Pharmacology & Therapeutics 76 (1), 38-44, 2004
2992004
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