Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions MC Kjellsson, LE Via, A Goh, D Weiner, KM Low, S Kern, G Pillai, ... Antimicrobial agents and chemotherapy 56 (1), 446-457, 2012 | 204 | 2012 |
Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it M Karlsson, DLI Janzén, L Durrieu, A Colman-Lerner, MC Kjellsson, ... BMC systems biology 9, 1-15, 2015 | 52 | 2015 |
Mechanistic modeling of pitavastatin disposition in sandwich-cultured human hepatocytes: a proteomics-informed bottom-up approach A Vildhede, A Mateus, EK Khan, Y Lai, M Karlgren, P Artursson, ... Drug Metabolism and Disposition 44 (4), 505-516, 2016 | 51 | 2016 |
The effects of dose staggering on metabolic drug–drug interactions J Yang, M Kjellsson, A Rostami-Hodjegan, GT Tucker European journal of pharmaceutical sciences 20 (2), 223-232, 2003 | 49 | 2003 |
Evidence-based design of fixed-dose combinations: principles and application to pediatric anti-tuberculosis therapy EM Svensson, G Yngman, P Denti, H McIlleron, MC Kjellsson, ... Clinical Pharmacokinetics 57 (5), 591-599, 2018 | 42 | 2018 |
Estimating bias in population parameters for some models for repeated measures ordinal data using NONMEM and NLMIXED S Jönsson, MC Kjellsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 31, 299-320, 2004 | 35 | 2004 |
The impact of misspecification of residual error or correlation structure on the type I error rate for covariate inclusion HE Silber, MC Kjellsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 36, 81-99, 2009 | 34 | 2009 |
Weight‐HbA1c‐insulin‐glucose model for describing disease progression of type 2 diabetes S Choy, MC Kjellsson, MO Karlsson, W de Winter CPT: pharmacometrics & systems pharmacology 5 (1), 11-19, 2016 | 28 | 2016 |
Comparison of proportional and differential odds models for mixed-effects analysis of categorical data MC Kjellsson, PH Zingmark, EN Jonsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 35, 483-501, 2008 | 28 | 2008 |
Evaluation of the nonparametric estimation method in NONMEM VI RM Savic, MC Kjellsson, MO Karlsson European journal of pharmaceutical sciences 37 (1), 27-35, 2009 | 26* | 2009 |
Longitudinal modeling of the relationship between mean plasma glucose and HbA1c following antidiabetic treatments JB Møller, RV Overgaard, MC Kjellsson, NR Kristensen, S Klim, ... CPT: Pharmacometrics & Systems Pharmacology 2 (10), 1-8, 2013 | 24 | 2013 |
A bounded integer model for rating and composite scale data GJ Wellhagen, MC Kjellsson, MO Karlsson The AAPS journal 21, 1-8, 2019 | 22 | 2019 |
Semimechanistic model describing gastric emptying and glucose absorption in healthy subjects and patients with type 2 diabetes O Alskär, JI Bagger, RM Røge, FK Knop, MO Karlsson, T Vilsbøll, ... The Journal of Clinical Pharmacology 56 (3), 340-348, 2016 | 21 | 2016 |
A model‐based approach to predict longitudinal HbA1c, using early phase glucose data from type 2 diabetes mellitus patients after anti‐diabetic treatment MC Kjellsson, VF Cosson, NA Mazer, N Frey, MO Karlsson The Journal of Clinical Pharmacology 53 (6), 589-600, 2013 | 21 | 2013 |
Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes E Nyman, YJW Rozendaal, G Helmlinger, B Hamrén, MC Kjellsson, ... Interface focus 6 (2), 20150075, 2016 | 20 | 2016 |
Modeling sleep data for a new drug in development using Markov mixed-effects models MC Kjellsson, D Ouellet, B Corrigan, MO Karlsson Pharmaceutical research 28, 2610-2627, 2011 | 20 | 2011 |
Model‐based interspecies scaling of glucose homeostasis O Alskär, MO Karlsson, MC Kjellsson CPT: Pharmacometrics & Systems Pharmacology 6 (11), 778-786, 2017 | 18 | 2017 |
Modeling of 24‐hour glucose and insulin profiles in patients with type 2 diabetes mellitus treated with biphasic insulin aspart RM Røge, S Klim, NR Kristensen, SH Ingwersen, MC Kjellsson The Journal of Clinical Pharmacology 54 (7), 809-817, 2014 | 17 | 2014 |
Modeling the disease progression from healthy to overt diabetes in ZDSD rats S Choy, W de Winter, MO Karlsson, MC Kjellsson The AAPS journal 18, 1203-1212, 2016 | 15 | 2016 |
Identification of the primary mechanism of action of an insulin secretagogue from meal test data in healthy volunteers based on an integrated glucose-insulin model S Choy, E Hénin, JS van der Walt, MC Kjellsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 40, 1-10, 2013 | 14 | 2013 |