Katherine A. de Villiers
Katherine A. de Villiers
Verified email at sun.ac.za
Title
Cited by
Cited by
Year
Haemozoin (β-haematin) biomineralization occurs by self-assembly near the lipid/water interface
TJ Egan, JYJ Chen, KA de Villiers, TE Mabotha, KJ Naidoo, KK Ncokazi, ...
FEBS letters 580 (21), 5105-5110, 2006
1622006
Speciation and structure of ferriprotoporphyrin IX in aqueous solution: spectroscopic and diffusion measurements demonstrate dimerization, but not μ-oxo dimer formation
KA de Villiers, CH Kaschula, TJ Egan, HM Marques
JBIC Journal of Biological Inorganic Chemistry 12 (1), 101-117, 2007
1582007
The crystal structure of halofantrine–ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials
KA de Villiers, HM Marques, TJ Egan
Journal of inorganic biochemistry 102 (8), 1660-1667, 2008
1352008
Crystallization of synthetic haemozoin (β-haematin) nucleated at the surface of lipid particles
AN Hoang, KK Ncokazi, KA de Villiers, DW Wright, TJ Egan
Dalton Transactions 39 (5), 1235-1244, 2010
902010
Speciation of ferriprotoporphyrin IX in aqueous and mixed aqueous solution is controlled by solvent identity, pH, and salt concentration
C Asher, KA de Villiers, TJ Egan
Inorganic chemistry 48 (16), 7994-8003, 2009
852009
Iron (III) protoporphyrin IX complexes of the antimalarial cinchona alkaloids quinine and quinidine
KA de Villiers, J Gildenhuys, T le Roex
ACS chemical biology 7 (4), 666-671, 2012
642012
The single crystal X-ray structure of β-hematin DMSO solvate grown in the presence of chloroquine, a β-hematin growth-rate inhibitor
J Gildenhuys, T Roex, TJ Egan, KA de Villiers
Journal of the American Chemical Society 135 (3), 1037-1047, 2013
632013
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis
KA De Villiers, TJ Egan
Molecules 14 (8), 2868-2887, 2009
522009
Solvent-induced effects: self-association of positively charged π systems
E Buisine, K De Villiers, TJ Egan, C Biot
Journal of the American Chemical Society 128 (37), 12122-12128, 2006
502006
Discriminating the intraerythrocytic lifecycle stages of the malaria parasite using synchrotron FT-IR microspectroscopy and an artificial neural network
GT Webster, KA De Villiers, TJ Egan, S Deed, L Tilley, MJ Tobin, ...
Analytical chemistry 81 (7), 2516-2524, 2009
472009
Discriminating the intraerythrocytic lifecycle stages of the malaria parasite using synchrotron FT-IR microspectroscopy and an artificial neural network
GT Webster, KA De Villiers, TJ Egan, S Deed, L Tilley, MJ Tobin, ...
Analytical chemistry 81 (7), 2516-2524, 2009
472009
Oriented nucleation of β-hematin crystals induced at various interfaces: Relevance to hemozoin formation
KA de Villiers, M Osipova, TE Mabotha, I Solomonov, Y Feldman, K Kjaer, ...
Crystal Growth and Design 9 (1), 626-632, 2008
292008
Hemozoin inhibiting 2-phenylbenzimidazoles active against malaria parasites
FP L'abbate, R Müller, R Openshaw, JM Combrinck, KA de Villiers, ...
European journal of medicinal chemistry 159, 243-254, 2018
152018
Alkoxide coordination of iron (III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution
J Gildenhuys, CJ Sammy, R Müller, VA Streltsov, T le Roex, D Kuter, ...
Dalton Transactions 44 (38), 16767-16777, 2015
132015
Insights into the initial stages of lipid-mediated haemozoin nucleation
D Kuter, R Mohunlal, SM Fitzroy, C Asher, PJ Smith, TJ Egan, ...
CrystEngComm 18 (27), 5177-5187, 2016
122016
Three 4-aminoquinolines of antimalarial interest
SA Bourne, K De Villiers, TJ Egan
Acta Crystallographica Section C: Crystal Structure Communications 62 (2 …, 2006
102006
The Effects of Quinoline and Non-quinoline Inhibitors on the Kinetics of Lipid-mediated β-Hematin Crystallization
SM Fitzroy, J Gildenhuys, T Olivier, NO Tshililo, D Kuter, KA de Villiers
Langmuir 33 (30), 7529-7537, 2017
92017
Design, Synthesis, and Evaluation of Novel Ferroquine and Phenylequine Analogues as Potential Antiplasmodial Agents
L Jacobs, C de Kock, KA de Villiers, PJ Smith, VJ Smith, WAL van Otterlo, ...
ChemMedChem 10 (12), 2099-2110, 2015
72015
Iron (III) Protoporphyrin IX and Hemozoin: Key Targets in the Chemotherapy of Malaria
KA de Villiers, TJ Egan
Handbook of Porphyrin Science (Volume 27) With Applications to Chemistry …, 2014
32014
Differential speciation of ferriprotoporphyrin IX in the presence of free base and diprotic 4-aminoquinoline antimalarial drugs
J Gildenhuys, R Müller, T le Roex, KA de Villiers
Solid State Sciences 65, 95-99, 2017
22017
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