| Structural insights into the South African HIV-1 subtype C protease: impact of hinge region dynamics and flap flexibility in drug resistance P Naicker, I Achilonu, S Fanucchi, M Fernandes, MAA Ibrahim, HW Dirr, ... Journal of Biomolecular Structure and Dynamics 31 (12), 1370-1380, 2013 | 48 | 2013 |
| Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases R Hurdayal, I Achilonu, D Choveaux, THT Coetzer, JPD Goldring Peptides 31 (4), 525-532, 2010 | 48 | 2010 |
| Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion T Zininga, I Achilonu, H Hoppe, E Prinsloo, HW Dirr, A Shonhai Cell Stress and Chaperones 21 (3), 499-513, 2016 | 47 | 2016 |
| Overexpression, purification and characterisation of the Plasmodium falciparum Hsp70-z (PfHsp70-z) protein T Zininga, I Achilonu, H Hoppe, E Prinsloo, HW Dirr, A Shonhai PLoS One 10 (6), e0129445, 2015 | 42 | 2015 |
| Structural and biochemical characterization of Plasmodium falciparum Hsp70‐x reveals functional versatility of its C‐terminal EEVN motif B Mabate, T Zininga, L Ramatsui, S Makumire, I Achilonu, HW Dirr, ... Proteins: Structure, Function, and Bioinformatics 86 (11), 1189-1201, 2018 | 40 | 2018 |
| Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70 T Zininga, OJ Pooe, PB Makhado, L Ramatsui, E Prinsloo, I Achilonu, ... Cell Stress and Chaperones 22 (5), 707-715, 2017 | 40 | 2017 |
| (−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional … T Zininga, L Ramatsui, PB Makhado, S Makumire, I Achilinou, H Hoppe, ... Molecules 22 (12), 2139, 2017 | 36 | 2017 |
| Role of individual histidines in the pH-dependent global stability of human chloride intracellular channel 1 I Achilonu, S Fanucchi, M Cross, M Fernandes, HW Dirr Biochemistry 51 (5), 995-1004, 2012 | 35 | 2012 |
| Purification and characterisation of recombinant human eukaryotic elongation factor 1 gamma I Achilonu, TP Siganunu, HW Dirr Protein expression and purification 99, 70-77, 2014 | 25 | 2014 |
| Comparative Characterization of Plasmodium falciparum Hsp70-1 Relative to E. coli DnaK Reveals the Functional Specificity of the Parasite Chaperone CM Lebepe, PR Matambanadzo, XH Makhoba, I Achilonu, T Zininga, ... Biomolecules 10 (6), 856, 2020 | 24 | 2020 |
| High yield purification of JNK1β1 and activation by in vitro reconstitution of the MEKK1→ MKK4→ JNK MAPK phosphorylation cascade GR Owen, I Achilonu, HW Dirr Protein expression and purification 87 (2), 87-99, 2013 | 23 | 2013 |
| Stability of the domain interface contributes towards the catalytic function at the H-site of class alpha glutathione transferase A1-1 D Balchin, S Fanucchi, I Achilonu, RJ Adamson, J Burke, M Fernandes, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (12), 2228-2233, 2010 | 23 | 2010 |
| SARS-CoV-2 Spike Protein Unlikely to Bind to Integrins via the Arg-Gly-Asp (RGD) Motif of the Receptor Binding Domain: Evidence From Structural Analysis and … H Othman, HB Messaoud, O Khamessi, H Ben-Mabrouk, K Ghedira, ... Frontiers in molecular biosciences 9, 834857, 2022 | 21 | 2022 |
| Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2–P3 α-ketoamide derivative and Pentagastrin: An in-silico drug discovery approach I Achilonu, EA Iwuchukwu, OJ Achilonu, MA Fernandes, Y Sayed Journal of Molecular Graphics and Modelling 101, 107730, 2020 | 21 | 2020 |
| Coping with the ESKAPE pathogens: Evolving strategies, challenges and future prospects C Aloke, I Achilonu Microbial Pathogenesis 175, 105963, 2023 | 19 | 2023 |
| Molecular dynamics and ligand docking of a hinge region variant of South African HIV-1 subtype C protease J Zondagh, V Balakrishnan, I Achilonu, HW Dirr, Y Sayed Journal of Molecular Graphics and Modelling 82, 1-11, 2018 | 18 | 2018 |
| Role of arginine 29 and glutamic acid 81 interactions in the conformational stability of human chloride intracellular channel 1 D Legg-E’Silva, I Achilonu, S Fanucchi, S Stoychev, M Fernandes, ... Biochemistry 51 (40), 7854-7862, 2012 | 17 | 2012 |
| The future of cassava in the era of biotechnology in Southern Africa S Otun, A Escrich, I Achilonu, M Rauwane, JA Lerma-Escalera, ... Critical Reviews in Biotechnology 43 (4), 594-612, 2023 | 16 | 2023 |
| Combating Lassa fever in West African sub-region: Progress, challenges, and future perspectives C Aloke, NA Obasi, PM Aja, CU Emelike, CO Egwu, O Jeje, CO Edeogu, ... Viruses 15 (1), 146, 2023 | 14 | 2023 |
| Current advances in the management of diabetes mellitus C Aloke, CO Egwu, PM Aja, NA Obasi, J Chukwu, BO Akumadu, PN Ogbu, ... Biomedicines 10 (10), 2436, 2022 | 14 | 2022 |
Yasien Sayed, PhDProfessor of Biochemistry, University of the Witwatersrand, JohannesburgVerified email at wits.ac.za
