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Kamal Kamal El Sayed Gadalla
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Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice
KKE Gadalla, MES Bailey, RC Spike, PD Ross, KT Woodard, SN Kalburgi, ...
Molecular Therapy 21 (1), 18-30, 2013
1642013
Radically truncated MeCP2 rescues Rett syndrome-like neurological defects
R Tillotson, J Selfridge, MV Koerner, KKE Gadalla, J Guy, D De Sousa, ...
Nature 550 (7676), 398-401, 2017
1472017
MeCP2 and Rett syndrome: reversibility and potential avenues for therapy
KKE Gadalla, MES Bailey, SR Cobb
Biochemical Journal 439 (1), 1-14, 2011
1382011
Development of a novel AAV gene therapy cassette with improved safety features and efficacy in a mouse model of Rett syndrome
KKE Gadalla, T Vudhironarit, RD Hector, S Sinnett, NG Bahey, ...
Molecular Therapy Methods & Clinical Development 5, 180-190, 2017
952017
Improved MECP2 gene therapy extends the survival of MeCP2-null mice without apparent toxicity after intracisternal delivery
SE Sinnett, RD Hector, KKE Gadalla, C Heindel, D Chen, V Zaric, ...
Molecular Therapy Methods & Clinical Development 5, 106-115, 2017
822017
Inhibition of Piezo1 attenuates demyelination in the central nervous system
M Velasco‐Estevez, KKE Gadalla, N Liñan‐Barba, S Cobb, KK Dev, ...
Glia 68 (2), 356-375, 2020
532020
Toxic effect of aflatoxin B1 and the role of recovery on the rat cerebral cortex and hippocampus
NG Bahey, HO Abd Elaziz, KKES Gadalla
Tissue and cell 47 (6), 559-566, 2015
422015
Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits
KKE Gadalla, PD Ross, JS Riddell, MES Bailey, SR Cobb
PloS one 9 (11), e112889, 2014
322014
Potential toxic effect of bisphenol A on the cardiac muscle of adult rat and the possible protective effect of Omega-3: a histological and immunohistochemical study
NG Bahey, HO Abd Elaziz, KKE Gadalla
Journal of microscopy and ultrastructure 7 (1), 1-8, 2019
292019
Cancer immunology
N Rezaei
Springer, 2015
24*2015
Gene therapy for Rett syndrome: prospects and challenges
KKE Gadalla, PD Ross, RD Hector, NG Bahey, MES Bailey, SR Cobb
Future Neurology 10 (5), 467-484, 2015
142015
Label-free imaging of thick tissue at 1550 nm using a femtosecond optical parametric generator
J Trägårdh, G Robb, KKE Gadalla, S Cobb, C Travis, GL Oppo, ...
Optics Letters 40 (15), 3484-3487, 2015
52015
Reduced axonal diameter of peripheral nerve fibers in a mouse model of Rett syndrome
NG Bahey, KKE Gadalla, R McGonigal, MES Bailey, JM Edgar, SR Cobb
Neuroscience 358, 261-268, 2017
42017
Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
SA Zlatic, D Duong, KKE Gadalla, B Murage, L Ping, R Shah, JJ Fink, ...
Iscience 25 (9), 2022
32022
Novel MECP2 gene therapy is effective in a multicenter study using two mouse models of Rett syndrome and is safe in non-human primates
S Powers, S Likhite, KK Gadalla, CJ Miranda, AJ Huffenberger, C Dennys, ...
Molecular Therapy 31 (9), 2767-2782, 2023
22023
Gene therapy and virus-based cancer vaccines
ML Salem, KKE Gadalla, BC Fielding, SH Thorne
Cancer Immunology: Bench to Bedside Immunotherapy of Cancers, 131-150, 2015
22015
Cancer vaccines
ML Salem, KKE Gadalla, BC Fielding, SH Thorne
Vectors (HSVVs) 137, 7.3, 2014
22014
Virus-mediated delivery of MECP2 as a potential tool for the treatment of Rett syndrome
KKES Gadalla
Institute of Neuroscience and Psychology, 2012
12012
An EXACT single gene circuit improves the safety of vector-derived MeCP2 expression in vivo
KK Gadalla, NG Bahey, S Thomson, P Ross, RD Hector, J Selfridge, ...
HUMAN GENE THERAPY 33 (23-24), A84-A84, 2022
2022
Gene transfer rescues audiogenic seizures in a mouse model of Fragile X syndrome
LC Kaminioti-Dumont, KK Gadalla, RD Hector, J Selfridge, E Osterweil, ...
HUMAN GENE THERAPY 33 (23-24), A84-A84, 2022
2022
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