BMC biotechnology Volume: 4 ISSN: 1472-6750 ISO Abbreviation: BMC Biotechnol. Publication Date: 2004 Dec MR Dyson, SP Shadbolt, KJ Vincent, RL Perera, J McCafferty Detail:, 0 | 371* | |
Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance A Wohlkonig, PF Chan, AP Fosberry, P Homes, J Huang, M Kranz, ... Nature structural & molecular biology 17 (9), 1152-1153, 2010 | 334 | 2010 |
Application of phage display to high throughput antibody generation and characterization DJ Schofield, AR Pope, V Clementel, J Buckell, SDJ Chapple, KF Clarke, ... Genome biology 8, 1-18, 2007 | 304 | 2007 |
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome AC Simon, JC Zhou, RL Perera, F van Deursen, C Evrin, ME Ivanova, ... Nature 510 (7504), 293-297, 2014 | 225 | 2014 |
A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA LA Yates, RJ Aramayo, N Pokhrel, CC Caldwell, JA Kaplan, RL Perera, ... Nature communications 9 (1), 5447, 2018 | 124 | 2018 |
Mechanism for priming DNA synthesis by yeast DNA polymerase α RL Perera, R Torella, S Klinge, ML Kilkenny, JD Maman, L Pellegrini Elife 2, e00482, 2013 | 117 | 2013 |
Flexible tethering of primase and DNA Pol α in the eukaryotic primosome R Núñez-Ramírez, S Klinge, L Sauguet, R Melero, MA Recuero-Checa, ... Nucleic acids research 39 (18), 8187-8199, 2011 | 77 | 2011 |
Structures of human primase reveal design of nucleotide elongation site and mode of Pol α tethering ML Kilkenny, MA Longo, RL Perera, L Pellegrini Proceedings of the National Academy of Sciences 110 (40), 15961-15966, 2013 | 73 | 2013 |
Shared active site architecture between the large subunit of eukaryotic primase and DNA photolyase L Sauguet, S Klinge, RL Perera, JD Maman, L Pellegrini PLoS One 5 (4), e10083, 2010 | 73 | 2010 |
Identification of soluble protein fragments by gene fragmentation and genetic selection MR Dyson, RL Perera, SP Shadbolt, L Biderman, K Bromek, NV Murzina, ... Nucleic acids research 36 (9), e51-e51, 2008 | 50 | 2008 |
A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing K Parthiban, RL Perera, M Sattar, Y Huang, S Mayle, E Masters, D Griffiths, ... MAbs 11 (5), 884-898, 2019 | 47 | 2019 |
A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome ML Kilkenny, G De Piccoli, RL Perera, K Labib, L Pellegrini Journal of Biological Chemistry 287 (28), 23740-23747, 2012 | 47 | 2012 |
Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries MR Dyson, E Masters, D Pazeraitis, RL Perera, JL Syrjanen, S Surade, ... MAbs 12 (1), 1829335, 2020 | 45 | 2020 |
Selecting for developability of polypeptide drugs in eukaryotic cell display systems J McCafferty, R Perera, MR Dyson, K Parthiban, JL Syrjanen US Patent 11,499,150, 2022 | | 2022 |
Engineered FHA domains R Perera, M Longo US Patent 11,214,791, 2022 | | 2022 |
Antibody like protein M Longo, R Perera US Patent 10,870,926, 2020 | | 2020 |
Antibody like protein M Longo, R Perera US Patent 10,370,776, 2019 | | 2019 |
Selecting for developability of polypeptide drugs in eukaryotic cell display systems J Mccafferty, R PERERA, MR Dyson, K PARTHIBAN, JL SYRJANEN | | 2019 |
Structural and mechanistic studies of Saccharomyces cerevisiae DNA polymerase α R Perera University of Cambridge, 2013 | | 2013 |