Prodrug strategies for enhancing the percutaneous absorption of drugs DD N’Da Molecules 19 (12), 20780-20807, 2014 | 150 | 2014 |
Considerations on the mechanism of action of artemisinin antimalarials: Part 1-The'carbon radical'and'heme'hypotheses R K. Haynes, KW Cheu, D N'Da, P Coghi, D Monti Infectious Disorders-Drug TargetsDisorders) 13 (4), 217-277, 2013 | 107 | 2013 |
Synthesis, characterization and antimalarial activity of quinoline–pyrimidine hybrids SI Pretorius, WJ Breytenbach, C De Kock, PJ Smith, DD N’Da Bioorganic & medicinal chemistry 21 (1), 269-277, 2013 | 105 | 2013 |
Recent progress in the development of anti-malarial quinolones RM Beteck, FJ Smit, RK Haynes, DD N’Da Malaria journal 13, 1-10, 2014 | 97 | 2014 |
An update on derivatisation and repurposing of clinical nitrofuran drugs NH Zuma, J Aucamp, DND David European Journal of Pharmaceutical Sciences 140, 105092, 2019 | 84 | 2019 |
Synthesis, in vitro antimalarial activity and cytotoxicity of novel 4-aminoquinolinyl-chalcone amides FJ Smit, DD N’Da Bioorganic & Medicinal Chemistry 22 (3), 1128-1138, 2014 | 71 | 2014 |
Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters FJ Smit, RA van Biljon, LM Birkholtz, DND David European journal of medicinal chemistry 90, 33-44, 2015 | 62 | 2015 |
Synthesis and in vitro biological evaluation of aminoacridines and artemisinin–acridine hybrids JP Joubert, FJ Smit, L Du Plessis, PJ Smith, DD N’Da European Journal of Pharmaceutical Sciences 56, 16-27, 2014 | 57 | 2014 |
Synthesis and in vitro antimalarial activity of a series of bisquinoline and bispyrrolo [1, 2a] quinoxaline compounds L Van Heerden, TT Cloete, JW Breytenbach, C de Kock, PJ Smith, ... European journal of medicinal chemistry 55, 335-345, 2012 | 55 | 2012 |
Synthesis, in vitro antiplasmodial and antiproliferative activities of a series of quinoline–ferrocene hybrids DD N’Da, PJ Smith Medicinal Chemistry Research 23, 1214-1224, 2014 | 51 | 2014 |
Antimalarial and anticancer activities of artemisinin–quinoline hybrid-dimers and pharmacokinetic properties in mice MC Lombard, DD N’Da, JC Breytenbach, NI Kolesnikova, CT Van Ba, ... European journal of pharmaceutical sciences 47 (5), 834-841, 2012 | 51 | 2012 |
Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids MC Lombard, DD N’Da, JC Breytenbach, PJ Smith, CA Lategan Bioorganic & medicinal chemistry letters 21 (6), 1683-1686, 2011 | 50 | 2011 |
Artemisinin–quinoline hybrid-dimers: Synthesis and in vitro antiplasmodial activity MC Lombard, DD N’Da, JC Breytenbach, PJ Smith, CA Lategan Bioorganic & medicinal chemistry letters 20 (23), 6975-6977, 2010 | 46 | 2010 |
Synthesis, in vitro antimalarial activities and cytotoxicities of amino-artemisinin-ferrocene derivatives C De Lange, D Coertzen, FJ Smit, JF Wentzel, HN Wong, LM Birkholtz, ... Bioorganic & medicinal chemistry letters 28 (3), 289-292, 2018 | 42 | 2018 |
Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1, 2-disubstituted ferrocene hybrids C De Lange, D Coertzen, FJ Smit, JF Wentzel, HN Wong, LM Birkholtz, ... Bioorganic & Medicinal Chemistry Letters 28 (19), 3161-3163, 2018 | 36 | 2018 |
Recent advances in the synthesis and development of nitroaromatics as anti-infective drugs C Kannigadu, DD N'Da Current Pharmaceutical Design 26 (36), 4658-4674, 2020 | 35 | 2020 |
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites RM Beteck, R Seldon, D Coertzen, ME van der Watt, J Reader, ... Communications Chemistry 1 (1), 62, 2018 | 34 | 2018 |
Synthesis, in vitro antiplasmodial activity and cytotoxicity of a series of artemisinin–triazine hybrids and hybrid-dimers TT Cloete, C de Kock, PJ Smith, DND David European journal of medicinal chemistry 76, 470-481, 2014 | 34 | 2014 |
Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids MC Lombard, DD N’Da, C Tran Van Ba, S Wein, J Norman, L Wiesner, ... Malaria Journal 12, 1-7, 2013 | 32 | 2013 |
The cytotoxic activity of macromolecular ferrocene conjugates against the Colo 320 DM human colon cancer line MT Johnson, E Kreft, DD N'Da, EW Neuse, CEJ van Rensburg Journal of Inorganic and Organometallic Polymers 13, 255-267, 2003 | 32 | 2003 |