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Frederick John Sheedy
Frederick John Sheedy
Unknown affiliation
Verified email at tcd.ie
Title
Cited by
Cited by
Year
Macrophages in atherosclerosis: a dynamic balance
KJ Moore, FJ Sheedy, EA Fisher
Nature Reviews Immunology 13 (10), 709-721, 2013
25582013
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
FJ Sheedy, E Palsson-McDermott, EJ Hennessy, C Martin, JJ O'leary, ...
Nature immunology 11 (2), 141-147, 2010
11842010
Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages
EM Palsson-McDermott, AM Curtis, G Goel, MAR Lauterbach, FJ Sheedy, ...
Cell metabolism 21 (1), 65-80, 2015
10932015
MicroRNAs: the fine-tuners of Toll-like receptor signalling
LA O'neill, FJ Sheedy, CE McCoy
Nature reviews immunology 11 (3), 163-175, 2011
10392011
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
FJ Sheedy, A Grebe, KJ Rayner, P Kalantari, B Ramkhelawon, ...
Nature immunology 14 (8), 812-820, 2013
9232013
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
KJ Rayner, CC Esau, FN Hussain, AL McDaniel, SM Marshall, ...
Nature 478 (7369), 404-407, 2011
8242011
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
KJ Rayner, FJ Sheedy, CC Esau, FN Hussain, RE Temel, S Parathath, ...
The Journal of clinical investigation 121 (7), 2921-2931, 2011
8062011
Turning 21: induction of miR-21 as a key switch in the inflammatory response
FJ Sheedy
Frontiers in immunology 6, 119312, 2015
4872015
MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis
M Ouimet, HN Ediriweera, UM Gundra, FJ Sheedy, B Ramkhelawon, ...
The Journal of clinical investigation 125 (12), 4334-4348, 2015
3602015
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
M Ouimet, S Koster, E Sakowski, B Ramkhelawon, C Van Solingen, ...
Nature immunology 17 (6), 677-686, 2016
3452016
IL-10 inhibits miR-155 induction by toll-like receptors
CE McCoy, FJ Sheedy, JE Qualls, SL Doyle, SR Quinn, PJ Murray, ...
Journal of Biological Chemistry 285 (27), 20492-20498, 2010
3392010
Adding fuel to fire: microRNAs as a new class of mediators of inflammation
FJ Sheedy, LAJ O’Neill
Annals of the rheumatic diseases 67 (Suppl 3), iii50-iii55, 2008
2862008
Cutting edge: Mycobacterium tuberculosis induces aerobic glycolysis in human alveolar macrophages that is required for control of intracellular bacillary replication
LE Gleeson, FJ Sheedy, EM Palsson-McDermott, D Triglia, SM O’Leary, ...
The Journal of Immunology 196 (6), 2444-2449, 2016
2822016
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
B Ramkhelawon, EJ Hennessy, M Ménager, TD Ray, FJ Sheedy, ...
Nature medicine 20 (4), 377-384, 2014
2712014
Platelet microparticles reprogram macrophage gene expression and function
B Laffont, A Corduan, M Rousseau, AC Duchez, CHC Lee, E Boilard, ...
Thrombosis and haemostasis 115 (02), 311-323, 2016
1812016
Mycobacterium tuberculosis limits host glycolysis and IL-1β by restriction of PFK-M via MicroRNA-21
EE Hackett, H Charles-Messance, SM O’Leary, LE Gleeson, ...
Cell reports 30 (1), 124-136. e4, 2020
1162020
The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling
FJ Sheedy, LAJ O’Neill
Journal of Leucocyte Biology 82 (2), 196-203, 2007
972007
Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6
EJ Hennessy, FJ Sheedy, D Santamaria, M Barbacid, LAJ O'Neill
Journal of Biological Chemistry 286 (29), 25531-25539, 2011
742011
IL-1 signaling in atherosclerosis: sibling rivalry
FJ Sheedy, KJ Moore
Nature immunology 14 (10), 1030-1032, 2013
702013
Metabolic reprogramming & inflammation: Fuelling the host response to pathogens
LE Gleeson, FJ Sheedy
Seminars in immunology 28 (5), 450-468, 2016
662016
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