Yun Chen
Yun Chen
Rocket Pharma
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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
Y Chen, GW Dorn
Science 340 (6131), 471-475, 2013
Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5
Y Chen, DH Gorski
Blood, The Journal of the American Society of Hematology 111 (3), 1217-1226, 2008
Mitochondrial fusion is essential for organelle function and cardiac homeostasis
Y Chen, Y Liu, GW Dorn
Circulation research 109 (12), 1327-1331, 2011
Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts
M Song, K Mihara, Y Chen, L Scorrano, GW Dorn II
Cell metabolism 21 (2), 273-286, 2015
Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca2+ Crosstalk
Y Chen, G Csordás, C Jowdy, TG Schneider, N Csordás, W Wang, Y Liu, ...
Circulation research 111 (7), 863-875, 2012
Osteocalcin signaling in myofibers is necessary and sufficient for optimum adaptation to exercise
P Mera, K Laue, M Ferron, C Confavreux, J Wei, M Galán-Díez, ...
Cell metabolism 23 (6), 1078-1092, 2016
Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling
A Kasahara, S Cipolat, Y Chen, GW Dorn, L Scorrano
Science 342 (6159), 734-737, 2013
Bax regulates primary necrosis through mitochondrial dynamics
RS Whelan, K Konstantinidis, AC Wei, Y Chen, DE Reyna, S Jha, Y Yang, ...
Proceedings of the National Academy of Sciences 109 (17), 6566-6571, 2012
Correcting mitochondrial fusion by manipulating mitofusin conformations
A Franco, RN Kitsis, JA Fleischer, E Gavathiotis, OS Kornfeld, G Gong, ...
Nature 540 (7631), 74-79, 2016
Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy
M Song, Y Chen, G Gong, E Murphy, PS Rabinovitch, GW Dorn
Circulation research 115 (3), 348-353, 2014
Label-free photoacoustic nanoscopy
A Danielli, KI Maslov, A Garcia-Uribe, AM Winkler, C Li, L Wang, Y Chen, ...
Journal of biomedical optics 19 (8), 086006, 2014
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
Y Chen, W Lewis, A Diwan, EHY Cheng, SJ Matkovich, GW Dorn
Proceedings of the National Academy of Sciences 107 (20), 9035-9042, 2010
Mitochondrial Contagion Induced by Parkin Deficiency in Drosophila Hearts and Its Containment by Suppressing Mitofusin
P Bhandari, M Song, Y Chen, Y Burelle, GW Dorn
Circulation research 114 (2), 257-265, 2014
Regulation of the Expression and Activity of the Antiangiogenic Homeobox Gene GAX/MEOX2 by ZEB2 and MicroRNA-221
Y Chen, M Banda, CL Speyer, JS Smith, AB Rabson, DH Gorski
Molecular and cellular biology 30 (15), 3902-3913, 2010
The Msx1 homeoprotein recruits polycomb to the nuclear periphery during development
J Wang, RM Kumar, VJ Biggs, H Lee, Y Chen, MH Kagey, RA Young, ...
Developmental cell 21 (3), 575-588, 2011
Targeting cyclophilin D and the mitochondrial permeability transition enhances β-cell survival and prevents diabetes in Pdx1 deficiency
K Fujimoto, Y Chen, KS Polonsky, GW Dorn
Proceedings of the National Academy of Sciences 107 (22), 10214-10219, 2010
The effect on MHC class II expression and apoptosis in placenta by IFNγ administration
Z Liu, Y Chen, Y Yang, J Peng
Contraception 65 (2), 177-184, 2002
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy
D Amgalan, TP Garner, R Pekson, XF Jia, M Yanamandala, V Paulino, ...
Nature cancer 1 (3), 315-328, 2020
The inhibitory effects of 5‐hydroxy‐3, 6, 7, 8, 3′, 4′‐hexamethoxyflavone on human colon cancer cells
P Qiu, H Guan, P Dong, S Guo, J Zheng, S Li, Y Chen, CT Ho, MH Pan, ...
Molecular nutrition & food research 55 (10), 1523-1532, 2011
The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences
Y Chen, AD Leal, S Patel, DH Gorski
Journal of Biological Chemistry 282 (1), 507-517, 2007
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