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Nicole D. Schartz
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The good, the bad, and the opportunities of the complement system in neurodegenerative disease
ND Schartz, AJ Tenner
Journal of Neuroinflammation 17 (1), 354, 2020
1882020
Status epilepticus triggers long-lasting activation of complement C1q-C3 signaling in the hippocampus that correlates with seizure frequency in experimental epilepsy
ND Schartz, SK Wyatt-Johnson, LR Price, SA Colin, AL Brewster
Neurobiology of Disease 109, 163-173, 2018
672018
Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus
ND Schartz, SA Herr, L Madsen, SJ Butts, C Torres, LB Mendez, ...
Scientific Reports 6 (1), 24988, 2016
562016
The role of the medial prefrontal cortex in regulating social familiarity-induced anxiolysis
EA Lungwitz, GD Stuber, PL Johnson, AD Dietrich, N Schartz, ...
Neuropsychopharmacology 39 (4), 1009-1019, 2014
382014
C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease
A Gomez-Arboledas, K Carvalho, G Balderrama-Gutierrez, SH Chu, ...
Acta neuropathologica communications 10 (1), 116, 2022
222022
Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression
K Carvalho, ND Schartz, G Balderrama-Gutierrez, HY Liang, SH Chu, ...
Journal of neuroinflammation 19 (1), 178, 2022
192022
Early treatment with C1 esterase inhibitor improves weight but not memory deficits in a rat model of status epilepticus
ND Schartz, AL Sommer, SA Colin, LB Mendez, AL Brewster
Physiology & behavior 212, 112705, 2019
142019
Impact of peripheral immune status on central molecular responses to facial nerve axotomy
DO Setter, EM Runge, ND Schartz, FM Kennedy, BL Brown, KP McMillan, ...
Brain, behavior, and immunity 68, 98-110, 2018
32018
Identification of a resilient mouse facial motoneuron population following target disconnection by injury or disease
DO Setter, MM Haulcomb, T Beahrs, RM Meadows, ND Schartz, ...
Restorative neurology and neuroscience 36 (3), 417-422, 2018
32018
C5aR1 signaling promotes region‐and age‐dependent synaptic pruning in models of Alzheimer's disease
A Gomez‐Arboledas, MI Fonseca, E Kramar, SH Chu, ND Schartz, ...
Alzheimer's & Dementia 20 (3), 2173-2190, 2024
12024
C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer’s model
ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ...
bioRxiv, 2023
12023
Gene expression profile analysis of immunodeficient mice after WT or mSOD1 immunoreconsitution reveals differential motoneuron death mechanisms after facial nerve axotomy
DO Setter, EM Runge, ND Schartz, VM Sanders, KJ Jones
The FASEB Journal 31, 747.1-747.1, 2017
12017
Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus
ND Schartz, A Aroor, Y Li, N Pinzón-Hoyos, AL Brewster
Frontiers in Molecular Neuroscience 16, 1265944, 2023
2023
67 Strategic targeting of complement to regulate neuroinflammation and synapse pruning in Alzheimer’s disease
A Tenner, N Schartz, H Liang, SH Chu, A Gomez-Arboledas, A Mortazavi
Immunobiology 228 (5), 152520, 2023
2023
Treatment with C5aR1 antagonist attenuates short‐term hippocampal memory decline and prevents DAM signature in Arctic mice.
ND Schartz, K Carvalho, HY Liang, SH Chu, A Mortazavi, AJ Tenner
Alzheimer's & Dementia 18, e066806, 2022
2022
C5aR1 deletion delays amyloid-associated inflammatory gene expression and microglial activation in the Arctic model of Alzheimer's disease
N Schartz, K Carvalho, A Gomez-Arboledas, G Balderrama-Gutierrez, ...
MOLECULAR IMMUNOLOGY 141, 142-142, 2022
2022
C5a overexpression alters gene expression and microglial activation in brain of the Arctic model of Alzheimer's disease
N Schartz, K Carvalho, T Petrisko, G Balderrama-Gutierrez, H Liang, ...
MOLECULAR IMMUNOLOGY 141, 140-141, 2022
2022
Plasma and serum neurofilament‐light levels increase in an age‐and pathology‐dependent manner in the Arctic mouse model of Alzheimer’s disease
ND Schartz, P Selvan, SH Chu, AJ Tenner
Alzheimer's & Dementia 17, e056343, 2021
2021
The Role of Complement C3 in the Hippocampal Pathology of Status Epilepticus
ND Schartz
Purdue University, 2019
2019
Low bone mass and strength in juvenile rats with acquired epilepsy.
HM Davis, ND Schartz, C Herrera, R Pacheco-Costa, SK Wyatt, ...
JOURNAL OF BONE AND MINERAL RESEARCH 32, S261-S261, 2017
2017
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