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Dinko Rekić
Dinko Rekić
Drug Development Leader at Alexion
Verified email at alexion.com - Homepage
Title
Cited by
Cited by
Year
Acute Exacerbation and Decline in Forced Vital Capacity Are Associated with Increased Mortality in Idiopathic Pulmonary Fibrosis
CBA Paterniti MO, Bi Y, Rekić D, Wang Y, Karimi-Shah BA
Annals of the American Thoracic Society, 2017
1522017
An oral antisense oligonucleotide for PCSK9 inhibition
P Gennemark, K Walter, N Clemmensen, D Rekić, CAM Nilsson, ...
Science Translational Medicine 13 (593), eabe9117, 2021
882021
Clinical drug–drug interaction evaluations to inform drug use and enable drug access
D Rekić, KS Reynolds, P Zhao, L Zhang, K Yoshida, M Sachar, MP Miller, ...
Journal of pharmaceutical sciences 106 (9), 2214-2218, 2017
732017
In vitro–in vivo extrapolation of metabolism-and transporter-mediated drug–drug interactions—overview of basic prediction methods
K Yoshida, P Zhao, L Zhang, DR Abernethy, D Rekić, KS Reynolds, ...
Journal of pharmaceutical sciences 106 (9), 2209-2213, 2017
672017
Toxicokinetics of mercury after long-term repeated exposure to thimerosal-containing vaccine
L Barregard, D Rekić, M Horvat, L Elmberg, T Lundh, O Zachrisson
Toxicological Sciences 120 (2), 499-506, 2011
642011
In silico prediction of efavirenz and rifampicin drug–drug interaction considering weight and CYP2B6 phenotype
D Rekić, D Röshammar, J Mukonzo, M Ashton
British journal of clinical pharmacology 71 (4), 536-543, 2011
532011
HIVAIDS Patients Display Lower Relative Bioavailability of Efavirenz than Healthy Subjects
JK Mukonzo, S Nanzigu, D Rekić, P Waako, D Roshammar, M Ashton, ...
Clinical pharmacokinetics 50 (8), 531-540, 2011
382011
Bilirubin—A Potential Marker of Drug Exposure in Atazanavir-Based Antiretroviral Therapy
D Rekić, O Clewe, D Röshammar, L Flamholc, A Sönnerborg, ...
The AAPS journal 13 (4), 598-605, 2011
202011
QT prolongation risk assessment in oncology: lessons learned from small‐molecule new drug applications approved during 2011‐2019
S Cohen‐Rabbie, AC Berges, D Rekić, J Parkinson, C Dota, ...
The Journal of Clinical Pharmacology 61 (8), 1106-1117, 2021
122021
AZD8233 antisense oligonucleotide targeting PCSK9 does not prolong QT interval
D Rekić, I Azarov, J Knöchel, V Sokolov, C Nilsson, L Wernevik, D Han, ...
British Journal of Clinical Pharmacology 88 (11), 4839-4844, 2022
102022
Etesian: a phase 2B study of the efficacy, safety and tolerability of Azd8233, a Pcsk9-targeted antisense oligonucleotide, in patients with dyslipidemia
MJ Koren, A Hofherr, J Schumi, D Rekic, J Knochel, CAM Nilsson, ...
Journal of the American College of Cardiology 79 (9_Supplement), 1475-1475, 2022
102022
Pharmacokinetics of roxadustat: a population analysis of 2855 dialysis-and non-dialysis-dependent patients with chronic kidney disease
D Rekić, V Kerbusch-Herben, M Någård, J Chou, J Huang, C Bradley, ...
Clinical Pharmacokinetics 60, 759-773, 2021
102021
Model based design and analysis of phase II HIV-1 trials
D Rekić, D Röshammar, USH Simonsson
Journal of pharmacokinetics and pharmacodynamics 40, 487-496, 2013
102013
Dapagliflozin pharmacokinetics is similar in adults with type 1 and type 2 diabetes mellitus
J Melin, W Tang, D Rekić, B Hamrén, RC Penland, DW Boulton, ...
The Journal of Clinical Pharmacology 62 (10), 1227-1235, 2022
92022
A semi-mechanistic exposure–response model to assess the effects of verinurad, a potent URAT1 inhibitor, on serum and urine uric acid in patients with hyperuricemia-associated …
J Leander, M Sunnåker, D Rekić, S Aksenov, UG Eriksson, S Johansson, ...
Journal of Pharmacokinetics and Pharmacodynamics 48, 525-541, 2021
82021
A disease progression model of longitudinal lung function decline in idiopathic pulmonary fibrosis patients
Y Bi, D Rekić, MO Paterniti, J Chen, A Marathe, BA Chowdhury, ...
Journal of pharmacokinetics and pharmacodynamics 48, 55-67, 2021
72021
A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II
J Knöchel, C Nilsson, B Carlsson, L Wernevik, A Hofherr, P Gennemark, ...
CPT: Pharmacometrics & Systems Pharmacology 11 (12), 1569-1577, 2022
42022
Bilirubin levels and kidney function decline: An analysis of clinical trial and real world data
Y Aoki, CS Cabrera, M Ouwens, K Bamberg, J Nyström, I Raz, BM Scirica, ...
Plos one 17 (6), e0269970, 2022
42022
Concentration‐QT modelling in early clinical oncology settings: Simulation evaluation of performance
G Cantet, A Berges, R O'Sullivan, S Cohen‐Rabbie, C Dota, V Dubois, ...
British Journal of Clinical Pharmacology 88 (3), 1010-1019, 2022
42022
Concentration‐QT modelling shows no evidence of clinically significant QT interval prolongation with capivasertib at expected therapeutic concentrations
V Voronova, M Cullberg, P Delff, J Parkinson, C Dota, G Schiavon, ...
British Journal of Clinical Pharmacology 88 (2), 858-864, 2022
42022
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