Aedin Culhane

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John QuackenbushHarvard T.H. Chan School of Public Health, Channing Division of Network Medicine, and Dana-FarberVerified email at hsph.harvard.edu
Benjamin Haibe-KainsScientist (Principal Investigator), Princess Margaret Cancer Centre, University Health NetworkVerified email at uhnresearch.ca
des higginsUniversity College DublinVerified email at ucd.ie
Professor William M. GallagherUCD Conway Institute, University College DublinVerified email at ucd.ie
Levi WaldronCity University of New York School of Public HealthVerified email at sph.cuny.edu
Matthew SchwedePhysicianVerified email at ucsf.edu
Donal J BrennanUniversity College DublinVerified email at ucd.ie
Michael BirrerProfessor Medicine HMSVerified email at partners.org
Michael J DuffySt Vincent's University Hospital and University College DublinVerified email at ucd.ie
Daniel GusenleitnerMercy BioAnalytics Inc.Verified email at mercybio.com
Chen MengBavarian Center for Biomolecular Mass Spectrometry (BayBioMS), TUM School of Life SciencesVerified email at tum.de
Amin Moghaddas GholamiTechnische Universität München, Chair for Proteomics and BioanalyticsVerified email at tum.de
Markus S. SchröderETH ZürichVerified email at biol.ethz.ch
Ronny Drapkin, MD, PhDUniversity of Pennsylvania, Perelman School of MedicineVerified email at pennmedicine.upenn.edu
Giovanni ParmigianiProfessor Department of Data Science, DFCIVerified email at dfci.harvard.edu
Ian B. Jeffery4D Pharma CorkVerified email at 4dpharmaplc.com
Darran O'ConnorRoyal College of Surgeons in IrelandVerified email at rcsi.ie
Markus RiesterNovartis Institutes for Biomedical ResearchVerified email at novartis.com
Bernhard KusterProfessor for Proteomics and BioanalyticsVerified email at tum.de
Alvis BrazmaSenior Scientist, European Bioinformatics Institute, EMBLVerified email at ebi.ac.uk

Aedin Culhane

Dana-Farber Cancer Institute, Harvard TH Chan School, University of Limerick

Verified email at ul.ie - Homepage

Bioinformatics tumor immunology Multiomics single cell matrix factorization


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The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018	2392	2018
Apoptosis: molecular regulation of cell death AJ Hale, CA Smith, LC Sutherland, VEA Stoneman, VL Longthorne, ... European Journal of Biochemistry 236 (1), 1-26, 1996	968	1996
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites B Sobhian, G Shao, DR Lilli, AC Culhane, LA Moreau, B Xia, ... Science 316 (5828), 1198-1202, 2007	737	2007
Repeatability of published microarray gene expression analyses J Ioannidis, DB Allison, CA Ball, I Coulibaly, X Cui, AC Culhane, M Falchi, ... Nature genetics 41 (2), 149-155, 2009	609	2009
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data IB Jeffery, DG Higgins, AC Culhane BMC bioinformatics 7 (1), 1-16, 2006	495	2006
MADE4: an R package for multivariate analysis of gene expression data AC Culhane, J Thioulouse, G Perrière, DG Higgins Bioinformatics 21 (11), 2789-2790, 2005	354	2005
survcomp: an R/Bioconductor package for performance assessment and comparison of survival models MS Schröder, AC Culhane, J Quackenbush, B Haibe-Kains Bioinformatics 27 (22), 3206-3208, 2011	331	2011
A three-gene model to robustly identify breast cancer molecular subtypes B Haibe-Kains, C Desmedt, S Loi, AC Culhane, G Bontempi, ... Journal of the National Cancer Institute 104 (4), 311-325, 2012	325	2012
Dimension reduction techniques for the integrative analysis of multi-omics data C Meng, OA Zeleznik, GG Thallinger, B Kuster, AM Gholami, AC Culhane Briefings in bioinformatics 17 (4), 628-641, 2016	283	2016
Between-group analysis of microarray data AC Culhane, G Perriere, EC Considine, TG Cotter, DG Higgins Bioinformatics 18 (12), 1600-1608, 2002	268	2002
A multivariate approach to the integration of multi-omics datasets C Meng, B Kuster, AC Culhane, AM Gholami BMC bioinformatics 15 (1), 1-13, 2014	229	2014
Taxonomy of breast cancer based on normal cell phenotype predicts outcome S Santagata, A Thakkar, A Ergonul, B Wang, T Woo, R Hu, JC Harrell, ... The Journal of clinical investigation 124 (2), 859-870, 2014	207	2014
Analysis of differential gene expression in colorectal cancer and stroma using fluorescence-activated cell sorting purification MJ Smith, AC Culhane, M Donovan, JC Coffey, BD Barry, MA Kelly, ... British journal of cancer 100 (9), 1452-1464, 2009	202	2009
Gene Expression Atlas update—a value-added database of microarray and sequencing-based functional genomics experiments M Kapushesky, T Adamusiak, T Burdett, A Culhane, A Farne, A Filippov, ... Nucleic acids research 40 (D1), D1077-D1081, 2012	180	2012
Risk prediction for late-stage ovarian cancer by meta-analysis of 1525 patient samples M Riester, W Wei, L Waldron, AC Culhane, L Trippa, E Oliva, S Kim, ... Journal of the National Cancer Institute 106 (5), dju048, 2014	177	2014
Cross-platform comparison and visualisation of gene expression data using co-inertia analysis AC Culhane, G Perrière, DG Higgins BMC bioinformatics 4 (1), 1-15, 2003	175	2003
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue DT Chen, A Nasir, A Culhane, C Venkataramu, W Fulp, R Rubio, T Wang, ... Breast cancer research and treatment 119 (2), 335-346, 2010	166	2010
Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled … JCE Lane, J Weaver, K Kostka, T Duarte-Salles, MTF Abrahao, H Alghoul, ... MedRxiv, 2020	164	2020
Expression Profiler: next generation—an online platform for analysis of microarray data M Kapushesky, P Kemmeren, AC Culhane, S Durinck, J Ihmels, C Körner, ... Nucleic acids research 32 (suppl_2), W465-W470, 2004	153	2004
Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment OutcomeGenomic Alterations in Ovarian Cancers ZC Wang, NJ Birkbak, AC Culhane, R Drapkin, A Fatima, R Tian, ... Clinical cancer research 18 (20), 5806-5815, 2012	151	2012

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