Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials MJ Sorich, MD Wiese, A Rowland, G Kichenadasse, RA McKinnon, ... Annals of Oncology 26 (1), 13-21, 2015 | 608 | 2015 |
Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer DW NEBERT, RA MCKINNON, A Puga DNA and cell biology 15 (4), 273-280, 1996 | 457 | 1996 |
Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer A Rowland, MM Dias, MD Wiese, G Kichenadasse, RA McKinnon, ... British journal of cancer 112 (12), 1888-1894, 2015 | 377 | 2015 |
Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance JO Miners, RA McKinnon, PI Mackenzie Toxicology 181, 453-456, 2002 | 276 | 2002 |
The UDP-glycosyltransferase (UGT) superfamily: new members, new functions, and novel paradigms R Meech, DG Hu, RA McKinnon, SN Mubarokah, AZ Haines, PC Nair, ... Physiological Reviews 99 (2), 1153-1222, 2019 | 261 | 2019 |
Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches JO Miners, PA Smith, MJ Sorich, RA McKinnon, PI Mackenzie Annu. Rev. Pharmacol. Toxicol. 44, 1-25, 2004 | 250 | 2004 |
Australian Pharmaceutical Formulary and Handbook 25th Edn L Sansom Pharmaceutical Society of Australia, 2021 | 245* | 2021 |
Cyp1a2 (-/-) null mutant mice develop normally but show deficient drug metabolism. HC Liang, H Li, RA McKinnon, JJ Duffy, SS Potter, A Puga, DW Nebert Proceedings of the National Academy of Sciences 93 (4), 1671-1676, 1996 | 203 | 1996 |
Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues. RA McKinnon, WM Burgess, PM Hall, SJ Roberts-Thomson, FJ Gonzalez, ... Gut 36 (2), 259-267, 1995 | 203 | 1995 |
Predicting response and toxicity to immune checkpoint inhibitors using routinely available blood and clinical markers AM Hopkins, A Rowland, G Kichenadasse, MD Wiese, H Gurney, ... British journal of cancer 117 (7), 913-920, 2017 | 173 | 2017 |
The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies KF Windmill, RA McKinnon, X Zhu, A Gaedigk, DM Grant, ME McManus Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 376 (1 …, 1997 | 165 | 1997 |
Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats Y Hu, RK Le Leu, CT Christophersen, R Somashekar, MA Conlon, ... Carcinogenesis 37 (4), 366-375, 2016 | 160 | 2016 |
CYP2C19 Genotype Has a Greater Effect on Adverse Cardiovascular Outcomes Following Percutaneous Coronary Intervention and in Asian Populations Treated … MJ Sorich, A Rowland, RA McKinnon, MD Wiese Circulation: cardiovascular genetics 7 (6), 895-902, 2014 | 149 | 2014 |
Comparison of linear and nonlinear classification algorithms for the prediction of drug and chemical metabolism by human UDP-glucuronosyltransferase isoforms MJ Sorich, JO Miners, RA McKinnon, DA Winkler, FR Burden, PA Smith Journal of chemical information and computer sciences 43 (6), 2019-2024, 2003 | 141 | 2003 |
Complementary and alternative medicines and dietary interventions in multiple sclerosis: what is being used in South Australia and why? EM Leong, SJ Semple, M Angley, W Siebert, J Petkov, RA McKinnon Complementary therapies in medicine 17 (4), 216-223, 2009 | 137 | 2009 |
Transcriptional regulation of human UDP-glucuronosyltransferase genes DG Hu, R Meech, RA McKinnon, PI Mackenzie Drug metabolism reviews 46 (4), 421-458, 2014 | 131 | 2014 |
Prasugrel vs. clopidogrel for cytochrome P450 2C19‐genotyped subgroups: integration of the TRITON‐TIMI 38 trial data MJ Sorich, A Vitry, MB Ward, JD Horowitz, RA McKinnon Journal of Thrombosis and Haemostasis 8 (8), 1678-1684, 2010 | 129 | 2010 |
Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance PI Mackenzie, JO Miners, RA McKinnon Walter de Gruyter 38 (9), 889-892, 2000 | 124 | 2000 |
Biosimilarity and interchangeability: principles and evidence: a systematic review RA McKinnon, M Cook, W Liauw, M Marabani, IC Marschner, NH Packer, ... BioDrugs 32, 27-52, 2018 | 116 | 2018 |
Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization RA McKinnon, PM Hall, LC Quattrochi, RH Tukey, ME McManus Hepatology 14 (5), 848-856, 1991 | 110* | 1991 |