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Utkarsh Doshi
Utkarsh Doshi
principal scientist 2 at Altria Client Services LLC
Verified email at altria.com - Homepage
Title
Cited by
Cited by
Year
Synthesis and anticonvulsant activity of new N-1′, N-3′-disubstituted-2′ H, 3H, 5′ H-spiro-(2-benzofuran-1, 4′-imidazolidine)-2′, 3, 5′-triones
HJ Patel, J Sarra, F Caruso, M Rossi, U Doshi, RA Stephani
Bioorganic & medicinal chemistry letters 16 (17), 4644-4647, 2006
632006
Human enterocytes as an in vitro model for the evaluation of intestinal drug metabolism: characterization of drug-metabolizing enzyme activities of cryopreserved human …
MCD Ho, N Ring, K Amaral, U Doshi, AP Li
Drug metabolism and disposition 45 (6), 686-691, 2017
592017
Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 …
J Zhang, U Doshi, A Suzuki, CW Chang, J Borlak, AP Li, W Tong
Chemico-biological interactions 255, 3-11, 2016
472016
Luciferin IPA–based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction
U Doshi, AP Li
Journal of biomolecular screening 16 (8), 903-909, 2011
352011
A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using …
AR Iskandar, F Zanetti, A Kondylis, F Martin, P Leroy, S Majeed, S Steiner, ...
Internal and Emergency Medicine 14, 863-883, 2019
332019
Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6 …
Q Yang, U Doshi, N Li, A P Li
Current drug metabolism 13 (7), 938-946, 2012
312012
Endoplasmic reticulum stress induction and ERK1/2 activation contribute to nefazodone-induced toxicity in hepatic cells
Z Ren, S Chen, J Zhang, U Doshi, AP Li, L Guo
Toxicological Sciences 154 (2), 368-380, 2016
282016
Prediction of the pharmacokinetics of pravastatin as an OATP substrate using plateable human hepatocytes with human plasma data and PBPK modeling
J Mao, U Doshi, M Wright, CECA Hop, AP Li, Y Chen
CPT: Pharmacometrics & Systems Pharmacology 7 (4), 251-258, 2018
262018
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries
D Utkarsh, C Loretz, AP Li
Chemico-Biological Interactions 255, 12-22, 2016
252016
Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4
A P Li, U Doshi
Drug Metabolism Letters 5 (3), 183-191, 2011
252011
Cytokine modulators in asthma: clinical perspectives
U DOSHI, P SALAT, V PARIKH
Indian journal of pharmacology 34 (1), 16-25, 2002
182002
Utility of pooled cryopreserved human enterocytes as an in vitro model for assessing intestinal clearance and drug-drug interactions
S Wong, U Doshi, P Vuong, N Liu, S Tay, H Le, M Kosaka, JR Kenny, ...
Drug Metabolism Letters 12 (1), 3-13, 2018
172018
A novel plated hepatocyte relay assay (PHRA) for in vitro evaluation of hepatic metabolic clearance of slowly metabolized compounds
CC Peng, U Doshi, C Prakash, A P Li
Drug metabolism letters 10 (1), 3-15, 2016
92016
Culture duration-, donor-, and medium-dependent changes in OATP1B3-mediated telmisartan uptake in human hepatocytes
Q Zhu, H Xia, C Q Xia, Q Yang, U Doshi, A P Li, M Liao
Drug metabolism letters 7 (2), 117-125, 2013
92013
Workshop Series to Identify, Discuss, and Develop Recommendations for the Optimal Generation and Use of In Vitro Assay Data for Tobacco Product Evaluation …
MM Moore, J Clements, P Desai, U Doshi, M Gaca, X Guo, T Hashizume, ...
Applied in vitro Toxicology 6 (2), 49-63, 2020
62020
In vitro evaluation of the metabolic stability of nine fragrance chemicals in trout and human hepatocytes
J Weeks, AP Li, U Doshi, K Johanning, PD Guiney
Journal of Applied Toxicology 40 (10), 1421-1434, 2020
52020
Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol
J Zhang, U Doshi, RL Wolz, P Kosachevsky, MJ Oldham, IG Gillman, ...
Toxicology in Vitro 82, 105352, 2022
32022
Integrated discrete multiple organ co-culture (IdMOC) system for the evaluation of multiple organ drug distribution, drug metabolism, and organ specific drug toxicity
AP Li, A Uzgare, H Saminathan, U Doshi
Drug metabolism reviews, 69-77, 2011
22011
Characterization of an air-liquid-interface (ALI) in vitro exposure system for e-vapor product
J Zhang, M Oldham, R Wolz, P Kosachevsky, U Doshi, I Gilman, KM Lee
58th Society of Toxicology, Baltimore, MD, 2019
12019
Isolation and cryopreservation of enterocytes for metabolism and uptake studies
AP Li, C Loretz, Q Yang, U Doshi
DRUG METABOLISM REVIEWS 48, 93-93, 2016
12016
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