Biophysical properties of the clinical-stage antibody landscape T Jain, T Sun, S Durand, A Hall, NR Houston, JH Nett, B Sharkey, ... Proceedings of the National Academy of Sciences 114 (5), 944-949, 2017 | 493 | 2017 |
Mechanical heterogeneities in model polymer glasses at small length scales K Yoshimoto, TS Jain, KV Workum, PF Nealey, JJ de Pablo Physical review letters 93 (17), 175501, 2004 | 292 | 2004 |
Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool Y Xu, W Roach, T Sun, T Jain, B Prinz, TY Yu, J Torrey, J Thomas, ... Protein Engineering, Design & Selection 26 (10), 663-670, 2013 | 216 | 2013 |
High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy Y Liu, I Caffry, J Wu, SB Geng, T Jain, T Sun, F Reid, Y Cao, P Estep, Y Yu, ... MAbs 6 (2), 483-492, 2014 | 156 | 2014 |
Deamidation and isomerization liability analysis of 131 clinical-stage antibodies X Lu, RP Nobrega, H Lynaugh, T Jain, K Barlow, T Boland, ... MAbs 11 (1), 45-57, 2019 | 105 | 2019 |
Local dynamic mechanical properties in model free-standing polymer thin films K Yoshimoto, TS Jain, PF Nealey, JJ De Pablo The Journal of chemical physics 122 (14), 2005 | 105 | 2005 |
High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice RL Kelly, T Sun, T Jain, I Caffry, Y Yu, Y Cao, H Lynaugh, M Brown, ... MAbs 7 (4), 770-777, 2015 | 98 | 2015 |
Monte Carlo simulation of free-standing polymer films near the glass transition temperature TS Jain, JJ de Pablo Macromolecules 35 (6), 2167-2176, 2002 | 80 | 2002 |
Investigation of transition states in bulk and freestanding film polymer glasses TS Jain, JJ de Pablo Physical review letters 92 (15), 155505, 2004 | 76 | 2004 |
Density-of-states Monte Carlo simulation of a binary glass Q Yan, TS Jain, JJ de Pablo Physical review letters 92 (23), 235701, 2004 | 68 | 2004 |
A biased Monte Carlo technique for calculation of the density of states of polymer films TS Jain, JJ de Pablo The Journal of chemical physics 116 (16), 7238-7243, 2002 | 65 | 2002 |
Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies R Yang, T Jain, H Lynaugh, RP Nobrega, X Lu, T Boland, I Burnina, T Sun, ... MAbs 9 (4), 646-653, 2017 | 58 | 2017 |
Materials and methods for creating imaging layers PF Nealey, TS Jain, EW Edwards, JJ De Pablo US Patent 7,514,764, 2009 | 58 | 2009 |
An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies P Estep, I Caffry, Y Yu, T Sun, Y Cao, H Lynaugh, T Jain, M Vásquez, ... MAbs 7 (3), 553-561, 2015 | 57 | 2015 |
The entropic cost of protein-protein association: a case study on acetylcholinesterase binding to fasciculin-2 DDL Minh, JM Bui, C Chang, T Jain, JMJ Swanson, JA McCammon Biophysical journal 89 (4), L25-L27, 2005 | 57 | 2005 |
Prediction of delayed retention of antibodies in hydrophobic interaction chromatography from sequence using machine learning T Jain, T Boland, A Lilov, I Burnina, M Brown, Y Xu, M Vásquez Bioinformatics 33 (23), 3758-3766, 2017 | 47 | 2017 |
Configurational‐bias sampling technique for predicting side‐chain conformations in proteins T Jain, DS Cerutti, JA McCammon Protein Science 15 (9), 2029-2039, 2006 | 47 | 2006 |
Influence of confinement on the vibrational density of states and the Boson peak in a polymer glass TS Jain, JJ de Pablo The Journal of chemical physics 120 (19), 9371-9375, 2004 | 42 | 2004 |
Role of local structure on motions on the potential energy landscape for a model supercooled polymer TS Jain, JJ de Pablo The Journal of chemical physics 122 (17), 2005 | 40 | 2005 |
Target-independent variable region mediated effects on antibody clearance can be FcRn independent RL Kelly, Y Yu, T Sun, I Caffry, H Lynaugh, M Brown, T Jain, Y Xu, ... MAbs 8 (7), 1269-1275, 2016 | 36 | 2016 |