Willem van Otterlo
Willem van Otterlo
Professor of Organic Chemistry, Department of Chemistry and Polymer Science, Stellenbsoch University
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Metathesis in the synthesis of aromatic compounds
WAL van Otterlo, CB De Koning
Chemical reviews 109 (8), 3743-3782, 2009
Modern methods for the sythesis of substituted naphthalenes
CB De Koning, AL Rousseau, WAL Van Otterlo
Pergamon-Elsevier Science Ltd, 2003
Isomerization of allylbenzenes
M Hassam, A Taher, GE Arnott, IR Green, WAL van Otterlo
Chemical reviews 115 (11), 5462-5569, 2015
Bioactivity-guided mapping and navigation of chemical space
S Renner, WAL Van Otterlo, M Dominguez Seoane, S Möcklinghoff, ...
Nature chemical biology 5 (8), 585-592, 2009
Ring-closing metathesis for the synthesis of 2H-and 4H-chromenes
WAL Van Otterlo, EL Ngidi, S Kuzvidza, GL Morgans, SS Moleele, ...
Tetrahedron 61 (42), 9996-10006, 2005
The synthesis of 2-and 3-aryl indoles and 1, 3, 4, 5-tetrahydropyrano [4, 3-b] indoles and their antibacterial and antifungal activity
TC Leboho, JP Michael, WAL van Otterlo, SF van Vuuren, CB de Koning
Bioorganic & medicinal chemistry letters 19 (17), 4948-4951, 2009
An isomerization-ring-closing metathesis strategy for the synthesis of substituted benzofurans
WAL van Otterlo, GL Morgans, LG Madeley, S Kuzvidza, SS Moleele, ...
Tetrahedron 61 (32), 7746-7755, 2005
Sequential isomerization and ring-closing metathesis: masked styryl and vinyloxyaryl groups for the synthesis of benzo-fused heterocycles
WAL van Otterlo, EL Ngidi, CB de Koning
Tetrahedron letters 44 (34), 6483-6486, 2003
Covalent‐allosteric kinase inhibitors
J Weisner, R Gontla, L van der Westhuizen, S Oeck, J Ketzer, P Janning, ...
Angewandte Chemie International Edition 54 (35), 10313-10316, 2015
Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor
VG Pawar, ML Sos, HB Rode, M Rabiller, S Heynck, WAL Van Otterlo, ...
Journal of medicinal chemistry 53 (7), 2892-2901, 2010
Metathesis reactions for the synthesis of ring-fused carbazoles
SC Pelly, CJ Parkinson, WAL Van Otterlo, CB De Koning
The Journal of Organic Chemistry 70 (25), 10474-10481, 2005
Synthesis of the dibenzopyrrocoline alkaloid skeleton: indolo [2, 1-a] isoquinolines and related analogues
ANC Lötter, R Pathak, TS Sello, MA Fernandes, WAL van Otterlo, ...
Tetrahedron 63 (10), 2263-2274, 2007
In search of a treatment for HIV–current therapies and the role of non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C Reynolds, CB de Koning, SC Pelly, WAL van Otterlo, ML Bode
Chemical Society Reviews 41 (13), 4657-4670, 2012
Ring-closing metathesis for the synthesis of benzo-fused bicyclic compounds
WAL van Otterlo, EL Ngidi, EM Coyanis, CB de Koning
Tetrahedron letters 44 (2), 311-313, 2003
Isomerization and ring-closing metathesis for the synthesis of 6-, 7-and 8-membered benzo-and pyrido-fused N, N-, N, O-and N, S-heterocycles
WAL van Otterlo, GL Morgans, SD Khanye, BAA Aderibigbe, JP Michael, ...
Tetrahedron letters 45 (50), 9171-9175, 2004
Conjugated polymer stabilized palladium nanoparticles as a versatile catalyst for Suzuki cross-coupling reactions for both aryl and heteroaryl bromide systems
RU Islam, MJ Witcomb, MS Scurrell, E Van Der Lingen, W Van Otterlo, ...
Catalysis Science & Technology 1 (2), 308-315, 2011
A concise synthesis of novel naphtho [a] carbazoles and benzo [c] carbazoles
R Pathak, JM Nhlapo, S Govender, JP Michael, WAL van Otterlo, ...
Tetrahedron 62 (12), 2820-2830, 2006
In search of a cytostatic agent derived from the alkaloid lycorine: Synthesis and growth inhibitory properties of lycorine derivatives
NM Evdokimov, D Lamoral-Theys, V Mathieu, A Andolfi, LV Frolova, ...
Bioorganic & medicinal chemistry 19 (23), 7252-7261, 2011
Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis
IV Magedov, L Frolova, M Manpadi, U Bhoga, H Tang, NM Evdokimov, ...
Journal of medicinal chemistry 54 (12), 4234-4246, 2011
Toward a cancer drug of fungal origin
A Kornienko, A Evidente, M Vurro, V Mathieu, A Cimmino, M Evidente, ...
Medicinal research reviews 35 (5), 937-967, 2015
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