Gordon Brown
Gordon Brown
Professor of Immunology, University of Exeter
Verified email at
Cited by
Cited by
Hidden killers: human fungal infections
GD Brown, DW Denning, NAR Gow, SM Levitz, MG Netea, TC White
Science translational medicine 4 (165), 165rv13-165rv13, 2012
A new receptor for β-glucans
GD Brown, S Gordon
Nature 413 (6851), 36-37, 2001
Macrophage receptors and immune recognition
PR Taylor, L Martinez-Pomares, M Stacey, HH Lin, GD Brown, S Gordon
Annu. Rev. Immunol. 23, 901-944, 2005
Dectin-1 mediates the biological effects of β-glucans
GD Brown, J Herre, DL Williams, JA Willment, ASJ Marshall, S Gordon
The Journal of experimental medicine 197 (9), 1119-1124, 2003
Dectin-1: a signalling non-TLR pattern-recognition receptor
GD Brown
Nature Reviews Immunology 6 (1), 33-43, 2006
Syk-and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
S LeibundGut-Landmann, O Groß, MJ Robinson, F Osorio, EC Slack, ...
Nature immunology 8 (6), 630-638, 2007
Dectin-1 is required for β-glucan recognition and control of fungal infection
PR Taylor, SV Tsoni, JA Willment, KM Dennehy, M Rosas, H Findon, ...
Nature immunology 8 (1), 31-38, 2007
Dectin-1 is a major β-glucan receptor on macrophages
GD Brown, PR Taylor, DM Reid, JA Willment, DL Williams, ...
The Journal of experimental medicine 196 (3), 407-412, 2002
An integrated model of the recognition of Candida albicans by the innate immune system
MG Netea, GD Brown, BJ Kullberg, NAR Gow
Nature Reviews Microbiology 6 (1), 67-78, 2008
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
NC Rogers, EC Slack, AD Edwards, MA Nolte, O Schulz, E Schweighoffer, ...
Immunity 22 (4), 507-517, 2005
Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis
ID Iliev, VA Funari, KD Taylor, Q Nguyen, CN Reyes, SP Strom, J Brown, ...
Science 336 (6086), 1314-1317, 2012
Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens
N Branzk, A Lubojemska, SE Hardison, Q Wang, MG Gutierrez, GD Brown, ...
Nature immunology 15 (11), 1017-1025, 2014
Fungal β-glucans and mammalian immunity
GD Brown, S Gordon
Immunity 19 (3), 311-315, 2003
The β-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages
PR Taylor, GD Brown, DM Reid, JA Willment, L Martinez-Pomares, ...
The Journal of immunology 169 (7), 3876-3882, 2002
Human dectin-1 deficiency and mucocutaneous fungal infections
B Ferwerda, G Ferwerda, TS Plantinga, JA Willment, AB Van Spriel, ...
New England Journal of Medicine 361 (18), 1760-1767, 2009
Tackling human fungal infections
GD Brown, DW Denning, SM Levitz
Science 336 (6082), 647-647, 2012
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
AG Hise, J Tomalka, S Ganesan, K Patel, BA Hall, GD Brown, ...
Cell host & microbe 5 (5), 487-497, 2009
The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus
C Steele, RR Rapaka, A Metz, SM Pop, DL Williams, S Gordon, JK Kolls, ...
PLoS pathogens 1 (4), e42, 2005
C-type lectins in immunity and homeostasis
GD Brown, JA Willment, L Whitehead
Nature Reviews Immunology 18 (6), 374-389, 2018
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection
MJ Robinson, F Osorio, M Rosas, RP Freitas, E Schweighoffer, O Groß, ...
Journal of Experimental Medicine 206 (9), 2037-2051, 2009
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