Jandeli Niemand
Jandeli Niemand
Department of Biochemistry, University of Pretoria
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Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities
LM Birkholtz, M Williams, J Niemand, AI Louw, L Persson, O Heby
Biochemical Journal 438 (2), 229-244, 2011
Discovery of novel alkylated (bis) urea and (bis) thiourea polyamine analogues with potent antimalarial activities
BK Verlinden, J Niemand, J Snyman, SK Sharma, RJ Beattie, PM Woster, ...
Journal of medicinal chemistry 54 (19), 6624-6633, 2011
Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation
R Van Biljon, R Van Wyk, HJ Painter, L Orchard, J Reader, J Niemand, ...
BMC genomics 20 (1), 1-16, 2019
Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum
K Clark, J Niemand, S Reeksting, S Smit, AC Van Brummelen, M Williams, ...
Amino acids 38 (2), 633-644, 2010
Exploring functional genomics for drug target and therapeutics discovery in Plasmodia
L Birkholtz, AC Van Brummelen, K Clark, J Niemand, E Maréchal, ...
Acta tropica 105 (2), 113-123, 2008
Polyamine uptake by the intraerythrocytic malaria parasite, Plasmodium falciparum
J Niemand, AI Louw, L Birkholtz, K Kirk
International journal for parasitology 42 (10), 921-929, 2012
Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites
R Van Biljon, J Niemand, R van Wyk, K Clark, B Verlinden, C Abrie, ...
Scientific reports 8 (1), 1-14, 2018
In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species
P Moyo, ME Botha, S Nondaba, J Niemand, VJ Maharaj, JN Eloff, AI Louw, ...
Journal of ethnopharmacology 185, 235-242, 2016
Morphological and Molecular Descriptors of the Developmental Cycle of Babesia divergens Parasites in Human Erythrocytes
I Rossouw, C Maritz-Olivier, J Niemand, R Van Biljon, A Smit, NA Olivier, ...
PLoS neglected tropical diseases 9 (5), e0003711, 2015
Interrogating alkyl and arylalkylpolyamino (bis) urea and (bis) thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum …
BK Verlinden, M De Beer, B Pachaiyappan, E Besaans, WA Andayi, ...
Bioorganic & medicinal chemistry 23 (16), 5131-5143, 2015
Bioassay-guided isolation and identification of gametocytocidal compounds from Artemisia afra (Asteraceae)
P Moyo, P Kunyane, MA Selepe, JN Eloff, J Niemand, AI Louw, ...
Malaria journal 18 (1), 1-11, 2019
Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials
ME van der Watt, J Reader, A Churchyard, SH Nondaba, SB Lauterbach, ...
Journal of Antimicrobial Chemotherapy 73 (5), 1279-1290, 2018
Anthracene-Polyamine Conjugates Inhibit In Vitro Proliferation of Intraerythrocytic Plasmodium falciparum Parasites
J Niemand, P Burger, BK Verlinden, J Reader, AM Joubert, A Kaiser, ...
Antimicrobial agents and chemotherapy 57 (6), 2874-2877, 2013
Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases
BJ Morahan, C Abrie, K Al-Hasani, MB Batty, V Corey, AN Cowell, ...
Communications biology 3 (1), 1-10, 2020
Understanding human genetic factors influencing primaquine safety and efficacy to guide primaquine roll-out in a pre-elimination setting in southern Africa
SS Awandu, J Raman, TI Makhanthisa, P Kruger, J Frean, T Bousema, ...
Malaria Journal 17 (1), 1-11, 2018
Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites
D Le Roux, PB Burger, J Niemand, A Grobler, P Urbán, ...
International Journal for Parasitology: Drugs and Drug Resistance 4 (1), 28-36, 2014
Biochemical characterisation of putrescine and spermidine uptake as a potential therapeutic target against the human malaria parasite, Plasmodium falciparum
J Niemand
University of Pretoria, 2012
Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential
J Niemand, L Birkholtz, AI Louw, K Kirk
Malaria Journal 9 (2), 1-1, 2010
A phage display study of interacting peptide binding partners of malarial S-Adenosylmethionine decarboxylase/Ornithine decarboxylase
J Niemand
University of Pretoria, 2008
Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites
J Niemand, R Van Biljon, M Van Der Watt, A Van Heerden, J Reader, ...
ACS Infectious Diseases 7 (10), 2904-2916, 2021
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