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Johan Flygare
Johan Flygare
Verified email at med.lu.se
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From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
SM Hattangadi, P Wong, L Zhang, J Flygare, HF Lodish
Blood, The Journal of the American Society of Hematology 118 (24), 6258-6268, 2011
5392011
Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation
W Hu, B Yuan, J Flygare, HF Lodish
Genes & development 25 (24), 2573-2578, 2011
2942011
Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis
NB Woods, A Muessig, M Schmidt, J Flygare, K Olsson, P Salmon, ...
Blood, The Journal of the American Society of Hematology 101 (4), 1284-1289, 2003
2892003
Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits
J Flygare, A Aspesi, JC Bailey, K Miyake, JM Caffrey, S Karlsson, SR Ellis
Blood 109 (3), 980-986, 2007
2382007
HIF1α synergizes with glucocorticoids to promote BFU-E progenitor self-renewal
J Flygare, VR Estrada, C Shin, S Gupta, HF Lodish
Blood, The Journal of the American Society of Hematology 117 (12), 3435-3444, 2011
1902011
Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia
J Flygare, T Kiefer, K Miyake, T Utsugisawa, I Hamaguchi, L Da Costa, ...
Blood 105 (12), 4627-4634, 2005
1552005
miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1
L Zhang, J Flygare, P Wong, B Lim, HF Lodish
Genes & development 25 (2), 119-124, 2011
1472011
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia
P Jaako, J Flygare, K Olsson, R Quere, M Ehinger, A Henson, S Ellis, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6087-6096, 2011
1452011
ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors
L Zhang, L Prak, V Rayon-Estrada, P Thiru, J Flygare, B Lim, HF Lodish
Nature 499 (7456), 92-96, 2013
1242013
Diamond-Blackfan anemia: erythropoiesis lost in translation
J Flygare, S Karlsson
Blood 109 (8), 3152-3154, 2007
1212007
From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones
H Lodish, J Flygare, S Chou
IUBMB life 62 (7), 492-496, 2010
1132010
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia
P Jaako, S Debnath, K Olsson, D Bryder, J Flygare, S Karlsson
Blood, The Journal of the American Society of Hematology 120 (11), 2225-2228, 2012
932012
Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond …
K Miyake, T Utsugisawa, J Flygare, T Kiefer, I Hamaguchi, J Richter, ...
Stem Cells 26 (2), 323-329, 2008
852008
Development of cellular models for ribosomal protein S19 (RPS19)-deficient Diamond–Blackfan anemia using inducible expression of siRNA against RPS19
K Miyake, J Flygare, T Kiefer, T Utsugisawa, J Richter, Z Ma, ...
Molecular Therapy 11 (4), 627-637, 2005
732005
Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond–Blackfan anemia improves following RPS19 gene transfer
I Hamaguchi, J Flygare, H Nishiura, ACM Brun, A Ooka, T Kiefer, Z Ma, ...
Molecular Therapy 7 (5), 613-622, 2003
652003
Defining the minimal factors required for erythropoiesis through direct lineage conversion
S Capellera-Garcia, J Pulecio, K Dhulipala, K Siva, V Rayon-Estrada, ...
Cell reports 15 (11), 2550-2562, 2016
582016
Erythropoiesis in the Rps19 disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia
H Matsson, EJ Davey, AS Fröjmark, K Miyake, T Utsugisawa, J Flygare, ...
Blood Cells, Molecules, and Diseases 36 (2), 259-264, 2006
502006
Gene therapy of Diamond Blackfan anemia CD34+ cells leads to improved erythroid development and engraftment following transplantation
J Flygare, K Olsson, J Richter, S Karlsson
Experimental Hematology 36 (11), 1428-1435, 2008
462008
Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells
S Chou, J Flygare, HF Lodish
Experimental hematology 41 (5), 479-490. e4, 2013
402013
Disruption of the 5S RNP–Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia
P Jaako, S Debnath, K Olsson, Y Zhang, J Flygare, MS Lindström, ...
Leukemia 29 (11), 2221-2229, 2015
392015
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