Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs SH Lee, S Ripke, BM Neale, SV Faraone, SM Purcell, RH Perlis, ... Nature Genetics 45 (9), 984-994, 2013 | 2405 | 2013 |
Functional impact of global rare copy number variation in autism spectrum disorders D Pinto, AT Pagnamenta, L Klei, R Anney, D Merico, R Regan, J Conroy, ... Nature 466 (7304), 368-372, 2010 | 2367 | 2010 |
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. S Jamain, H Quach, C Betancur, M Råstam, C Colineaux, IC Gillberg, ... Nature Genetics 34 (1), 27-29, 2003 | 2270 | 2003 |
Patterns and rates of exonic de novo mutations in autism spectrum disorders BM Neale, Y Kou, L Liu, A Ma’Ayan, KE Samocha, A Sabo, CF Lin, ... Nature 485 (7397), 242-245, 2012 | 2086 | 2012 |
Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ... Cell 180 (3), 568-584. e23, 2020 | 2008 | 2020 |
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders CM Durand, C Betancur, TM Boeckers, J Bockmann, P Chaste, ... Nature Genetics 39 (1), 25-27, 2007 | 1938 | 2007 |
Mapping autism risk loci using genetic linkage and chromosomal rearrangements Nature genetics 39 (3), 319-328, 2007 | 1671 | 2007 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1460 | 2018 |
Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting C Betancur Brain Research 1380, 42-77, 2011 | 1209 | 2011 |
Convergence of genes and cellular pathways dysregulated in autism spectrum disorders D Pinto, E Delaby, D Merico, M Barbosa, A Merikangas, L Klei, ... The American Journal of Human Genetics 94 (5), 677-694, 2014 | 1127 | 2014 |
A genome-wide linkage and association scan reveals novel loci for autism LA Weiss, DE Arking, ... Nature 461 (7265), 802-808, 2009 | 810 | 2009 |
A genome-wide scan for common alleles affecting risk for autism R Anney, L Klei, D Pinto, R Regan, J Conroy, TR Magalhaes, C Correia, ... Human Molecular Genetics 19 (20), 4072-4082, 2010 | 738 | 2010 |
Meta-analysis of SHANK mutations in autism spectrum disorders: a gradient of severity in cognitive Impairments CS Leblond, C Nava, A Polge, J Gauthier, G Huguet, S Lumbroso, ... PLoS Genetics 10 (9), e1004580, 2014 | 662 | 2014 |
Abnormal melatonin synthesis in autism spectrum disorders J Melke, HG Botros, P Chaste, C Betancur, G Nygren, H Anckarsäter, ... Molecular Psychiatry 13 (1), 90-98, 2008 | 629 | 2008 |
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium Nature Neuroscience 18 (2), 199-209, 2015 | 540 | 2015 |
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders DJ Weiner, EM Wigdor, S Ripke, RK Walters, JA Kosmicki, J Grove, ... Nature Genetics 49 (7), 978, 2017 | 499 | 2017 |
Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders CS Leblond, J Heinrich, R Delorme, C Proepper, C Betancur, G Huguet, ... PLoS Genetics 8 (2), e1002521, 2012 | 493 | 2012 |
Individual common variants exert weak effects on risk for autism spectrum disorders R Anney, L Klei, D Pinto, J Almeida, E Bacchelli, G Baird, N Bolshakova, ... Human Molecular Genetics 21 (21), 4781-4792, 2012 | 457 | 2012 |
Linkage and association of the glutamate receptor 6 gene with autism S Jamain, C Betancur, H Quach, A Philippe, M Fellous, B Giros, C Gillberg, ... Molecular Psychiatry 7 (3), 302-310, 2002 | 414 | 2002 |
The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders C Betancur, T Sakurai, JD Buxbaum Trends in Neurosciences 32 (7), 402-412, 2009 | 368 | 2009 |