| The ‘Digital Twin’ to enable the vision of precision cardiology J Corral-Acero, F Margara, M Marciniak, C Rodero, F Loncaric, Y Feng, ... European Heart Journal 41 (18), 4556-4564, 2020 | 549 | 2020 |
| Minimal model for human ventricular action potentials in tissue A Bueno-Orovio, EM Cherry, FH Fenton Journal of Theoretical Biology 253 (3), 544-560, 2008 | 523 | 2008 |
| Fourier spectral methods for fractional-in-space reaction-diffusion equations A Bueno-Orovio, D Kay, K Burrage BIT Numerical Mathematics 54 (4), 937-954, 2014 | 364 | 2014 |
| Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology OJ Britton, A Bueno-Orovio, K Van Ammel, H Rong Lu, R Towart, ... Proceedings of the National Academy of Sciences of the United States of …, 2013 | 356 | 2013 |
| Human in silico drug trials demonstrate higher accuracy than animal models in predicting clinical pro-arrhythmic cardiotoxicity E Passini, OJ Britton, HR Lu, J Rohrbacher, AN Hermans, DJ Gallacher, ... Frontiers in Physiology 8, 668, 2017 | 300 | 2017 |
| Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization A Bueno-Orovio, D Kay, V Grau, B Rodriguez, K Burrage Journal of the Royal Society Interface 11 (97), 20140352, 2014 | 243 | 2014 |
| Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block J Tomek, A Bueno-Orovio, E Passini, X Zhou, A Minchole, O Britton, ... eLife 8, e48890, 2019 | 191 | 2019 |
| Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm A Muszkiewicz, OJ Britton, P Gemmell, E Passini, C Sánchez, X Zhou, ... Progress in Biophysics and Molecular Biology 120 (1-3), 115-127, 2015 | 189 | 2015 |
| Spectral methods for partial differential equations in irregular domains: the spectral smoothed boundary method A Bueno-Orovio, VM Pérez-García, FH Fenton SIAM Journal of Scientific Computing 28 (3), 886-900, 2006 | 176 | 2006 |
| Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy E Passini, A Mincholé, R Coppini, E Cerbai, B Rodriguez, S Severi, ... Journal of Molecular and Cellular Cardiology 96, 72-81, 2016 | 139 | 2016 |
| Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation C Sánchez, A Bueno-Orovio, E Wettwer, S Loose, J Simon, U Ravens, ... PLoS ONE 9 (8), e105897, 2014 | 128 | 2014 |
| Continuous adjoint approach for the Spalart-Allmaras model in aerodynamic optimization A Bueno-Orovio, C Castro, F Palacios, E Zuazua AIAA Journal 50 (3), 631-646, 2012 | 120 | 2012 |
| Na/K pump regulation of cardiac repolarization: insights from a systems biology approach A Bueno-Orovio, C Sánchez, E Pueyo, B Rodriguez Pflügers Archiv - European Journal of Physiology 466 (2), 183-193, 2014 | 95 | 2014 |
| Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase SN Reilly, X Liu, R Carnicer, A Recalde, A Muszkiewicz, R Jayaram, ... Science Translational Medicine 8 (340), 340ra74, 2016 | 89 | 2016 |
| Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions L Cardone-Noott, A Bueno-Orovio, A Minchole, N Zemzemi, B Rodriguez Europace 18 (suppl_4), iv4-iv15, 2016 | 88 | 2016 |
| In vivo and in silico investigation into mechanisms of frequency dependence of repolarization alternans in human ventricular cardiomyocytes X Zhou, A Bueno-Orovio, M Orini, B Hanson, MP Hayward, P Taggart, ... Circulation Research 118, 266-278, 2016 | 88 | 2016 |
| Toward a broader view of mechanisms of drug cardiotoxicity P Mamoshina, B Rodriguez, A Bueno-Orovio Cell Reports Medicine 2 (3), 100216, 2021 | 86 | 2021 |
| General principles for the validation of proarrhythmia risk prediction models: an extension of the CiPA in silico strategy Z Li, GR Mirams, T Yoshinaga, BJ Ridder, X Han, JE Chen, ... Clinical Pharmacology & Therapeutics 107 (1), 102-111, 2020 | 80 | 2020 |
| In-silico human electro-mechanical ventricular modelling and simulation for drug-induced pro-arrhythmia and inotropic risk assessment F Margara, ZJ Wang, F Levrero-Florencio, A Santiago, M Vázquez, ... Progress in Biophysics and Molecular Biology 159, 58-74, 2021 | 75 | 2021 |
| Chaste: cancer, heart and soft tissue environment FR Cooper, RE Baker, MO Bernabeu, R Bordas, L Bowler, ... Journal of Open Source Software 5 (47), 1848, 2020 | 75 | 2020 |
Blanca RodriguezUniversity of OxfordVerified email at cs.ox.ac.uk
