| Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding PCF CHEUNG, IP SALT, SP DAVIES, DG HARDIE, D CARLING Biochemical Journal 346 (3), 659-669, 2000 | 830 | 2000 |
| AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the α2 isoform I Salt, JW Celler, SA Hawley, A Prescott, A Woods, D Carling, DG Hardie Biochemical Journal 334 (1), 177-187, 1998 | 542 | 1998 |
| 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase. PA Lochhead, IP Salt, KS Walker, DG Hardie, C Sutherland Diabetes 49 (6), 896-903, 2000 | 523 | 2000 |
| AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge DG HARDIE, IP SALT, SA HAWLEY, SP DAVIES Biochemical Journal 338 (3), 717-722, 1999 | 507 | 1999 |
| AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β cells, and may regulate insulin release IP Salt, G Johnson, SJH Ashcroft, DG Hardie Biochemical Journal 335 (3), 533-539, 1998 | 506 | 1998 |
| Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells VA Morrow, F Foufelle, JMC Connell, JR Petrie, GW Gould, IP Salt Journal of Biological Chemistry 278 (34), 31629-31639, 2003 | 436 | 2003 |
| Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation S Bijland, SJ Mancini, IP Salt Clinical science 124 (8), 491-507, 2013 | 339 | 2013 |
| The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels SA Hawley, RJ Ford, BK Smith, GJ Gowans, SJ Mancini, RD Pitt, EA Day, ... Diabetes 65 (9), 2784-2794, 2016 | 312 | 2016 |
| The α1 and α2 isoforms of the AMP‐activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro A Woods, I Salt, J Scott, DG Hardie, D Carling FEBS letters 397 (2-3), 347-351, 1996 | 302 | 1996 |
| Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression G da Silva Xavier, I Leclerc, IP Salt, B Doiron, DG Hardie, A Kahn, ... Proceedings of the National Academy of Sciences 97 (8), 4023-4028, 2000 | 264 | 2000 |
| Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase. LG Fryer, E Hajduch, F Rencurel, IP Salt, HS Hundal, DG Hardie, ... Diabetes 49 (12), 1978-1985, 2000 | 236 | 2000 |
| Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and-independent mechanisms SJ Mancini, D Boyd, OJ Katwan, A Strembitska, TA Almabrouk, ... Scientific reports 8 (1), 5276, 2018 | 220 | 2018 |
| AMP-activated protein kinase: an ubiquitous signaling pathway with key roles in the cardiovascular system IP Salt, DG Hardie Circulation research 120 (11), 1825-1841, 2017 | 185 | 2017 |
| 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. IP Salt, JM Connell, GW Gould Diabetes 49 (10), 1649-1656, 2000 | 160 | 2000 |
| Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation IP Salt, TM Palmer Expert opinion on investigational drugs 21 (8), 1155-1167, 2012 | 148 | 2012 |
| The role of insulin and the adipocytokines in regulation of vascular endothelial function SA Ritchie, MA Ewart, CG Perry, JMC Connell, IP Salt Clinical science 107 (6), 519-532, 2004 | 147 | 2004 |
| AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production JA Reihill, MA Ewart, DG Hardie, IP Salt Biochemical and biophysical research communications 354 (4), 1084-1088, 2007 | 135 | 2007 |
| Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms SC Chen, R Brooks, J Houskeeper, SK Bremner, J Dunlop, B Viollet, ... Molecular and cellular endocrinology 440, 57-68, 2017 | 124 | 2017 |
| High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells IP Salt, VA Morrow, FM Brandie, JMC Connell, JR Petrie Journal of Biological Chemistry 278 (21), 18791-18797, 2003 | 122 | 2003 |
| Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance? LML Hall, CN Moran, GR Milne, J Wilson, NG MacFarlane, NG Forouhi, ... PloS one 5 (12), e14197, 2010 | 119 | 2010 |
David Grahame HardieUniversity of DundeeVerified email at dundee.ac.uk
