| Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ... New England Journal of Medicine 366 (20), 1905-1913, 2012 | 901 | 2012 |
| Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid LeukemiaISM Approach to Therapy Selection T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ... Cancer discovery 3 (12), 1416-1429, 2013 | 481* | 2013 |
| Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ... Blood, The Journal of the American Society of Hematology 121 (22), 4541-4550, 2013 | 345 | 2013 |
| Comparison of solution-based exome capture methods for next generation sequencing AM Sulonen, P Ellonen, H Almusa, M Lepistö, S Eldfors, S Hannula, ... Genome biology 12, 1-18, 2011 | 342 | 2011 |
| Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3 EM Haapaniemi, M Kaustio, HLM Rajala, AJ van Adrichem, L Kainulainen, ... Blood, The Journal of the American Society of Hematology 125 (4), 639-648, 2015 | 308 | 2015 |
| Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target O Dufva, M Kankainen, T Kelkka, N Sekiguchi, SA Awad, S Eldfors, ... Nature communications 9 (1), 1567, 2018 | 140 | 2018 |
| Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, EI Andersson, ... Leukemia 28 (8), 1738-1742, 2014 | 132 | 2014 |
| Implementing a functional precision medicine tumor board for acute myeloid leukemia D Malani, A Kumar, O Brück, M Kontro, B Yadav, M Hellesøy, ... Cancer Discovery 12 (2), 388-401, 2022 | 130 | 2022 |
| Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis P Savola, T Kelkka, HL Rajala, A Kuuliala, K Kuuliala, S Eldfors, ... Nature communications 8 (1), 15869, 2017 | 124 | 2017 |
| High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia EI Andersson, T Tanahashi, N Sekiguchi, VR Gasparini, S Bortoluzzi, ... Blood, The Journal of the American Society of Hematology 128 (20), 2465-2468, 2016 | 116 | 2016 |
| Comprehensive drug testing of patient-derived conditionally reprogrammed cells from castration-resistant prostate cancer K Saeed, V Rahkama, S Eldfors, D Bychkov, JP Mpindi, B Yadav, ... European urology 71 (3), 319-327, 2017 | 100 | 2017 |
| HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia M Kontro, A Kumar, MM Majumder, S Eldfors, A Parsons, T Pemovska, ... Leukemia 31 (2), 301-309, 2017 | 98 | 2017 |
| Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling EI Andersson, S Pützer, B Yadav, O Dufva, S Khan, L He, L Sellner, ... Leukemia 32 (3), 774-787, 2018 | 96 | 2018 |
| Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia E Andersson, H Kuusanmäki, S Bortoluzzi, S Lagström, A Parsons, ... Leukemia 30 (5), 1204-1208, 2016 | 91 | 2016 |
| Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation EI Andersson, HLM Rajala, S Eldfors, P Ellonen, T Olson, A Jerez, ... Blood cancer journal 3 (12), e168-e168, 2013 | 84 | 2013 |
| Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia H Kuusanmäki, O Dufva, M Vähä-Koskela, AM Leppä, J Huuhtanen, ... Blood 141 (13), 1610-1625, 2023 | 69 | 2023 |
| Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia JL Kivioja, A Thanasopoulou, A Kumar, M Kontro, B Yadav, MM Majumder, ... Leukemia 33 (6), 1360-1372, 2019 | 60 | 2019 |
| Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML D Malani, A Murumägi, B Yadav, M Kontro, S Eldfors, A Kumar, ... Leukemia 31 (5), 1187-1195, 2017 | 59 | 2017 |
| Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia S Adnan Awad, M Kankainen, T Ojala, P Koskenvesa, S Eldfors, ... Blood advances 4 (3), 546-559, 2020 | 58 | 2020 |
| Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia S Eldfors, H Kuusanmäki, M Kontro, MM Majumder, A Parsons, H Edgren, ... Leukemia 31 (1), 51-57, 2017 | 58 | 2017 |
Caroline HeckmanUniversity of Helsinki, Institute for Molecular Medicine Finland FIMM-HiLIFEVerified email at helsinki.fi
