Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients S Jarius, K Ruprecht, B Wildemann, T Kuempfel, M Ringelstein, C Geis, ... Journal of neuroinflammation 9, 1-17, 2012 | 867 | 2012 |
Animal models of ischemic stroke and their application in clinical research F Fluri, MK Schuhmann, C Kleinschnitz Drug design, development and therapy, 3445-3454, 2015 | 778 | 2015 |
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis C Kleinschnitz, G Stoll, M Bendszus, K Schuh, HU Pauer, P Burfeind, ... The Journal of experimental medicine 203 (3), 513-518, 2006 | 547 | 2006 |
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration C Kleinschnitz, H Grund, K Wingler, ME Armitage, E Jones, M Mittal, ... PLoS biology 8 (9), e1000479, 2010 | 512 | 2010 |
Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding C Kleinschnitz, M Pozgajova, M Pham, M Bendszus, B Nieswandt, G Stoll Circulation 115 (17), 2323-2330, 2007 | 470 | 2007 |
Neuromyelitis optica: evaluation of 871 attacks and 1,153 treatment courses I Kleiter, A Gahlen, N Borisow, K Fischer, KD Wernecke, B Wegner, ... Annals of neurology 79 (2), 206-216, 2016 | 428 | 2016 |
Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation C Kleinschnitz, N Schwab, P Kraft, I Hagedorn, A Dreykluft, T Schwarz, ... Blood, The Journal of the American Society of Hematology 115 (18), 3835-3842, 2010 | 404 | 2010 |
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature C Kleinschnitz, P Kraft, A Dreykluft, I Hagedorn, K Göbel, MK Schuhmann, ... Blood, The Journal of the American Society of Hematology 121 (4), 679-691, 2013 | 393 | 2013 |
The changing landscape for stroke prevention in AF: findings from the GLORIA-AF registry phase 2 MV Huisman, KJ Rothman, M Paquette, C Teutsch, HC Diener, SJ Dubner, ... Journal of the American College of Cardiology 69 (7), 777-785, 2017 | 352 | 2017 |
Failure of natalizumab to prevent relapses in neuromyelitis optica I Kleiter, K Hellwig, A Berthele, T Kümpfel, RA Linker, HP Hartung, F Paul, ... Archives of neurology 69 (2), 239-245, 2012 | 343 | 2012 |
Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation A Braun, D Varga-Szabo, C Kleinschnitz, I Pleines, M Bender, M Austinat, ... Blood, The Journal of the American Society of Hematology 113 (9), 2056-2063, 2009 | 340 | 2009 |
STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death A Berna-Erro, A Braun, R Kraft, C Kleinschnitz, MK Schuhmann, ... Science signaling 2 (93), ra67-ra67, 2009 | 336 | 2009 |
Neuroprotection for ischaemic stroke: translation from the bench to the bedside BA Sutherland, J Minnerup, JS Balami, F Arba, AM Buchan, ... International Journal of Stroke 7 (5), 407-418, 2012 | 333 | 2012 |
The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction D Varga-Szabo, A Braun, C Kleinschnitz, M Bender, I Pleines, M Pham, ... The Journal of experimental medicine 205 (7), 1583-1591, 2008 | 308 | 2008 |
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment G Stoll, C Kleinschnitz, B Nieswandt Blood, The Journal of the American Society of Hematology 112 (9), 3555-3562, 2008 | 295 | 2008 |
Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study T Hagenacker, CD Wurster, R Günther, O Schreiber-Katz, A Osmanovic, ... The Lancet Neurology 19 (4), 317-325, 2020 | 286 | 2020 |
Thromboinflammation in stroke brain damage SF De Meyer, F Denorme, F Langhauser, E Geuss, F Fluri, C Kleinschnitz Stroke 47 (4), 1165-1172, 2016 | 286 | 2016 |
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis O Salomon, DM Steinberg, M Zucker, D Varon, A Zivelin, U Seligsohn Thrombosis and haemostasis 105 (02), 269-273, 2011 | 264 | 2011 |
Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding I Hagedorn, S Schmidbauer, I Pleines, C Kleinschnitz, U Kronthaler, ... Circulation 121 (13), 1510-1517, 2010 | 242 | 2010 |
Neuroprotection for stroke: current status and future perspectives J Minnerup, BA Sutherland, AM Buchan, C Kleinschnitz International journal of molecular sciences 13 (9), 11753-11772, 2012 | 231 | 2012 |