Intestinal absorption and liver uptake of medium-chain fatty acids in non-anaesthetized pigs E Guillot, P Vaugelade, P Lemarchali, AR Rat British Journal of Nutrition 69 (2), 431-442, 1993 | 152 | 1993 |
PCSK9 modulates the secretion but not the cellular uptake of lipoprotein (a) ex vivo: an effect blunted by alirocumab EF Villard, A Thedrez, J Blankenstein, M Croyal, TTT Tran, B Poirier, ... JACC: Basic to Translational Science 1 (6), 419-427, 2016 | 119 | 2016 |
Comparative alpha-1 adrenoceptor subtype selectivity and functional uroselectivity of alpha-1 adrenoceptor antagonists DJ Martin, P Lluel, E Guillot, A Coste, D Jammes, I Angel Journal of Pharmacology and Experimental Therapeutics 282 (1), 228-235, 1997 | 108 | 1997 |
Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner SI Nishio, Y Gibert, L Berekelya, L Bernard, F Brunet, E Guillot, JC Le Bail, ... Molecular endocrinology 26 (8), 1316-1326, 2012 | 86 | 2012 |
Involvement of capsaicin-sensitive nerves in the regulation of glucose tolerance in diabetic rats E Guillot, A Coste, I Angel Life sciences 59 (12), 969-977, 1996 | 51 | 1996 |
SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents G Griebel, P Pichat, MP Pruniaux, S Beeské, M Lopez-Grancha, E Genet, ... Pharmacology Biochemistry and Behavior 102 (2), 203-214, 2012 | 50 | 2012 |
Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice S Migrenne, A Lacombe, AL Lefevre, MP Pruniaux, E Guillot, AM Galzin, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009 | 48 | 2009 |
PCSK9 inhibition with alirocumab reduces lipoprotein (a) levels in nonhuman primates by lowering apolipoprotein (a) production rate M Croyal, TTT Tran, RH Blanchard, JC Le Bail, EF Villard, B Poirier, ... Clinical Science 132 (10), 1075-1083, 2018 | 45 | 2018 |
The complexity of lipoprotein (a) lowering by PCSK9 monoclonal antibodies G Lambert, A Thedrez, M Croyal, S Ramin-Mangata, D Couret, N Diotel, ... Clinical science 131 (4), 261-268, 2017 | 44 | 2017 |
The Central Cannabinoid CB1 Receptor Is Required for Diet‐Induced Obesity and Rimonabant's Antiobesity Effects in Mice Z Pang, NN Wu, W Zhao, DC Chain, E Schaffer, X Zhang, P Yamdagni, ... Obesity 19 (10), 1923-1934, 2011 | 39 | 2011 |
Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1 P Mougenot, C Namane, E Fett, F Camy, R Dadji-Faïhun, G Langot, ... Bioorganic & medicinal chemistry letters 22 (7), 2497-2502, 2012 | 36 | 2012 |
Intestinal absorption of medium chain fatty acids: in vivo studies in pigs devoid of exocrine pancreatic secretion E Guillot, P Lemarchal, T Dhorne, A Rerat British Journal of Nutrition 72 (4), 545-553, 1994 | 36 | 1994 |
Beneficial effect of a chronic treatment with rimonabant on pancreatic function and β-cell morphology in Zucker Fatty rats VF Duvivier, L Delafoy-Plasse, V Delion, P Lechevalier, JC Le Bail, ... European journal of pharmacology 616 (1-3), 314-320, 2009 | 31 | 2009 |
Localization and phenotypic characterization of brainstem neurons activated by rimonabant and WIN55, 212-2 J Jelsing, AM Galzin, E Guillot, MP Pruniaux, PJ Larsen, N Vrang Brain research bulletin 78 (4-5), 202-210, 2009 | 31 | 2009 |
Lipoprotein (a) cellular uptake ex vivo and hepatic capture in vivo is insensitive to PCSK9 inhibition with alirocumab K Chemello, S Beeské, TT Trang Tran, V Blanchard, EF Villard, B Poirier, ... Basic to Translational Science 5 (6), 549-557, 2020 | 25 | 2020 |
Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis A Guillon, J Pardessus, P Lhommet, C Parent, R Respaud, D Marchand, ... MAbs 11 (2), 297-304, 2019 | 22 | 2019 |
Pharmacological characterization of muscarinic receptors implicated in rabbit detrusor muscle contraction and activation of inositol phospholipid hydrolysis in rabbit detrusor … M Barras, A Coste, MT Eon, E Guillot Fundamental & clinical pharmacology 13 (5), 562-570, 1999 | 19 | 1999 |
Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D O Venier, C Pascal, A Braun, C Namane, P Mougenot, O Crespin, ... Bioorganic & medicinal chemistry letters 23 (8), 2414-2421, 2013 | 17 | 2013 |
High glucose activates YAP signaling to promote vascular inflammation J Ortillon, JC Le Bail, E Villard, B Léger, B Poirier, C Girardot, S Beeske, ... Frontiers in Physiology 12, 665994, 2021 | 15 | 2021 |
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (Part I) Z Gao, WJ Hurst, E Guillot, W Czechtizky, U Lukasczyk, R Nagorny, ... Bioorganic & medicinal chemistry letters 23 (11), 3416-3420, 2013 | 15 | 2013 |