| Raf kinases: function, regulation and role in human cancer DT Leicht, V Balan, A Kaplun, V Singh-Gupta, L Kaplun, M Dobson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1196-1212, 2007 | 391 | 2007 |
| Life span extension and neuronal cell protection by Drosophila nicotinamidase V Balan, GS Miller, L Kaplun, K Balan, ZZ Chong, F Li, A Kaplun, ... Journal of Biological Chemistry 283 (41), 27810-27819, 2008 | 205 | 2008 |
| Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase V Balan, DT Leicht, J Zhu, K Balan, A Kaplun, V Singh-Gupta, J Qin, ... Molecular biology of the cell 17 (3), 1141-1153, 2006 | 106 | 2006 |
| Structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from Escherichia coli A Kaplun, M Vyazmensky, Y Zherdev, I Belenky, A Slutzker, S Mendel, ... Journal of molecular biology 357 (3), 951-963, 2006 | 84 | 2006 |
| The natural tumor suppressor protein maspin and potential application in non small cell lung cancer F Lonardo, X Li, A Kaplun, A Soubani, S Sethi, S Gadgeel, S Sheng Current pharmaceutical design 16 (16), 1877-1881, 2010 | 77 | 2010 |
| Glyoxylate carboligase lacks the canonical active site glutamate of thiamine-dependent enzymes A Kaplun, E Binshtein, M Vyazmensky, A Steinmetz, Z Barak, ... Nature chemical biology 4 (2), 113-118, 2008 | 77 | 2008 |
| Acetohydroxyacid synthase isozyme I from Escherichia coli has unique catalytic and regulatory properties V Vinogradov, M Vyazmensky, S Engel, I Belenky, A Kaplun, O Kryukov, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (3), 356-363, 2006 | 63 | 2006 |
| Tumor Suppressor Maspin as a Rheostat in HDAC Regulation to Achieve the Fine-Tuning of Epithelial Homeostasis A Kaplun, S Dzinic, M Margarida Bernardo, S Sheng Critical reviews in eukaryotic gene expression 22 (3), 249, 2012 | 55 | 2012 |
| Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (α … K Tittmann, K Schröder, R Golbik, J McCourt, A Kaplun, RG Duggleby, ... Biochemistry 43 (27), 8652-8661, 2004 | 51 | 2004 |
| Maspin reprograms the gene expression profile of prostate carcinoma cells for differentiation MM Bernardo, Y Meng, J Lockett, G Dyson, A Dombkowski, A Kaplun, X Li, ... Genes & cancer 2 (11), 1009-1022, 2011 | 45 | 2011 |
| HDAC1 Inhibition by Maspin Abrogates Epigenetic Silencing of Glutathione S-Transferase Pi in Prostate Carcinoma Cells X Li, A Kaplun, F Lonardo, E Heath, FH Sarkar, J Irish, W Sakr, S Sheng Molecular Cancer Research 9 (6), 733-745, 2011 | 31 | 2011 |
| Monitoring the acetohydroxy acid synthase reaction and related carboligations by circular dichroism spectroscopy M Vinogradov, A Kaplun, M Vyazmensky, S Engel, R Golbik, K Tittmann, ... Analytical biochemistry 342 (1), 126-133, 2005 | 30 | 2005 |
| Maspin expression in prostate tumor elicits host anti-tumor immunity SH Dzinic, K Chen, A Thakur, A Kaplun, RD Bonfil, X Li, J Liu, ... Oncotarget 5 (22), 11225, 2014 | 27 | 2014 |
| Identification of an intrinsic determinant critical for maspin subcellular localization and function SH Dzinic, A Kaplun, X Li, M Bernardo, Y Meng, I Dean, D Krass, ... PloS one 8 (11), e74502, 2013 | 27 | 2013 |
| Maspin expression in prostate tumor cells averts stemness and stratifies drug sensitivity MM Bernardo, A Kaplun, SH Dzinic, X Li, J Irish, A Mujagic, B Jakupovic, ... Cancer Research 75 (18), 3970-3979, 2015 | 25 | 2015 |
| PGMD: a comprehensive manually curated pharmacogenomic database A Kaplun, JD Hogan, F Schacherer, AP Peter, S Krishna, BR Braun, ... The Pharmacogenomics Journal 16 (2), 124-128, 2016 | 21 | 2016 |
| A clinically validated whole genome pipeline for structural variant detection and analysis N Neerman, G Faust, N Meeks, S Modai, L Kalfon, T Falik-Zaccai, ... BMC genomics 20, 1-8, 2019 | 20 | 2019 |
| MEK-1 activates C-Raf through a Ras-independent mechanism DT Leicht, V Balan, J Zhu, A Kaplun, A Bronisz, A Rana, G Tzivion Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (5), 976-986, 2013 | 20 | 2013 |
| The secretion and biological function of tumor suppressor maspin as an exosome cargo protein I Dean, SH Dzinic, MM Bernardo, Y Zou, V Kimler, X Li, A Kaplun, ... Oncotarget 8 (5), 8043, 2017 | 18 | 2017 |
| Establishing and validating regulatory regions for variant annotation and expression analysis A Kaplun, M Krull, K Lakshman, V Matys, B Lewicki, JD Hogan BMC genomics 17, 219-227, 2016 | 18 | 2016 |
Guri TzivionProfessor, Department of Biochemistry, Cell Biology, and Genetics, American University of AntiguaVerified email at auamed.net
