11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer? KH Storbeck, LM Bloem, D Africander, L Schloms, P Swart, AC Swart Molecular and cellular endocrinology 377 (1-2), 135-146, 2013 | 190 | 2013 |
Inhibition of tumour promotion in mouse skin by extracts of rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia), unique South African herbal teas J Marnewick, E Joubert, S Joseph, S Swanevelder, P Swart, ... Cancer letters 224 (2), 193-202, 2005 | 158 | 2005 |
Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion … JL Marnewick, FH Van der Westhuizen, E Joubert, S Swanevelder, ... Food and Chemical Toxicology 47 (1), 220-229, 2009 | 148 | 2009 |
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase P Swart, AC Swart, MR Waterman, RW Estabrook, JI Mason The Journal of Clinical Endocrinology & Metabolism 77 (1), 98-102, 1993 | 140 | 1993 |
The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: quantification of steroid intermediates and end products in H295R cells L Schloms, KH Storbeck, P Swart, WCA Gelderblom, AC Swart The Journal of steroid biochemistry and molecular biology 128 (3-5), 128-138, 2012 | 119 | 2012 |
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione AC Swart, L Schloms, KH Storbeck, LM Bloem, T du Toit, JL Quanson, ... The Journal of steroid biochemistry and molecular biology 138, 132-142, 2013 | 107 | 2013 |
Lipoxygenases: from isolation to application S Hayward, T Cilliers, P Swart Comprehensive reviews in food science and food safety 16 (1), 199-211, 2017 | 90 | 2017 |
A microbiological, biochemical and sensory characterisation of bovine milk treated by heat and ultraviolet (UV) light for manufacturing Cheddar cheese FP Cilliers, PA Gouws, T Koutchma, Y Engelbrecht, C Adriaanse, P Swart Innovative Food Science & Emerging Technologies 23, 94-106, 2014 | 81 | 2014 |
Estrogenic activity, chemical levels and health risk assessment of municipal distribution point water from Pretoria and Cape Town, South Africa MC Van Zijl, NH Aneck-Hahn, P Swart, S Hayward, B Genthe, C De Jager Chemosphere 186, 305-313, 2017 | 75 | 2017 |
Discovery of Compound A–a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity E Lesovaya, A Yemelyanov, AC Swart, P Swart, G Haegeman, ... Oncotarget 6 (31), 30730, 2015 | 72 | 2015 |
Mechanism for the stabilization in vivo of the aziridine precursor 2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride by serum proteins A Louw, P Swart, SS de Kock, KJ van der Merwe Biochemical pharmacology 53 (2), 189-197, 1997 | 65 | 1997 |
Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas LM Bloem, KH Storbeck, P Swart, T du Toit, L Schloms, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 153, 80-92, 2015 | 59 | 2015 |
A single amino acid residue, Ala 105, confers 16α-hydroxylase activity to human cytochrome P450 17α-hydroxylase/17, 20 lyase AC Swart, KH Storbeck, P Swart The Journal of steroid biochemistry and molecular biology 119 (3-5), 112-120, 2010 | 51 | 2010 |
Cytochrome b5: novel roles in steroidogenesis KH Storbeck, AC Swart, P Goosen, P Swart Molecular and cellular endocrinology 371 (1-2), 87-99, 2013 | 48 | 2013 |
Functional expression and characterisation of human cytochrome P45017α in Pichia pastoris NW Kolar, AC Swart, JI Mason, P Swart Journal of biotechnology 129 (4), 635-644, 2007 | 47 | 2007 |
Anti-Inflammatory Effects of Aspalathus linearis and Cyclopia spp. Extracts in a UVB/Keratinocyte (HaCaT) Model Utilising Interleukin-1α Accumulation as Biomarker T Magcwebeba, P Swart, S Swanevelder, E Joubert, W Gelderblom Molecules 21 (10), 1323, 2016 | 45 | 2016 |
The influence of Sutherlandia frutescens on adrenal steroidogenic cytochrome P450 enzymes D Prevoo, P Swart, AC Swart Journal of ethnopharmacology 118 (1), 118-126, 2008 | 43 | 2008 |
Biological activities of the shrub Salsola tuberculatiformis Botsch.: Contraceptive or stress alleviator? P Swart, AC Swart, A Louw, KJ van der Merwe Bioessays 25 (6), 612-619, 2003 | 43 | 2003 |
Rooibos influences glucocorticoid levels and steroid ratios in vivo and in vitro: A natural approach in the management of stress and metabolic disorders? L Schloms, C Smith, KH Storbeck, JL Marnewick, P Swart, AC Swart Molecular nutrition & food research 58 (3), 537-549, 2014 | 35 | 2014 |
The development of an ultra performance liquid chromatography-coupled atmospheric pressure chemical ionization mass spectrometry assay for seven adrenal steroids KH Storbeck, NW Kolar, M Stander, AC Swart, D Prevoo, P Swart Analytical biochemistry 372 (1), 11-20, 2008 | 35 | 2008 |