Follow
Debashis Ghosh
Debashis Ghosh
Professor, Department of Pharmacology, SUNY Upstate
Verified email at upstate.edu
Title
Cited by
Cited by
Year
Short-Chain Dehydrogenases/Reductases (SDR)
H Jörnvall, B Persson, S Krook, Maria, Atrian, R Gonzalez-Duarte, ...
Biochemistry 34 (18), 6003-6013, 1995
15991995
Structural basis for androgen specificity and oestrogen synthesis in human aromatase
D Ghosh, J Griswold, M Erman, W Pangborn
Nature 457 (7226), 219-223, 2009
6352009
Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 Å resolution
D Ghosh, VZ Pletnev, DW Zhu, Z Wawrzak, WL Duax, W Pangborn, ...
Structure 3 (5), 503-513, 1995
3721995
Three-dimensional structure of holo 3 alpha, 20 beta-hydroxysteroid dehydrogenase: a member of a short-chain dehydrogenase family.
D Ghosh, CM Weeks, P Grochulski, WL Duax, M Erman, RL Rimsay, ...
Proceedings of the National Academy of Sciences 88 (22), 10064-10068, 1991
3171991
The refined three-dimensional structure of 3α, 20β-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
D Ghosh, Z Wawrzak, CM Weeks, WL Duax, M Erman
Structure 2 (7), 629-640, 1994
2851994
Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis
N Galitsky, V Cody, A Wojtczak, D Ghosh, JR Luft, W Pangborn, L English
Acta Crystallographica Section D: Biological Crystallography 57 (8), 1101-1109, 2001
2832001
Structure of human estrone sulfatase suggests functional roles of membrane association
FG Hernandez-Guzman, T Higashiyama, W Pangborn, Y Osawa, ...
Journal of Biological Chemistry 278 (25), 22989-22997, 2003
2022003
Human peroxiredoxin 1 and 2 are not duplicate proteins: the unique presence of CYS83 in Prx1 underscores the structural and functional differences between Prx1 and Prx2
WS Lee, KS Choi, J Riddell, C Ip, D Ghosh, JH Park, YM Park
Journal of Biological Chemistry 282 (30), 22011-22022, 2007
1942007
Novel aromatase inhibitors by structure-guided design
D Ghosh, J Lo, D Morton, D Valette, J Xi, J Griswold, S Hubbell, C Egbuta, ...
Journal of medicinal chemistry 55 (19), 8464-8476, 2012
1932012
Human sulfatases: a structural perspective to catalysis
D Ghosh
Cellular and Molecular Life Sciences 64 (15), 2013-2022, 2007
1532007
Structure of the ternary complex of human 17β-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+
MW Sawicki, M Erman, T Puranen, P Vihko, D Ghosh
Proceedings of the National Academy of Sciences 96 (3), 840-845, 1999
1521999
Structure of uncomplexed and linoleate-bound Candida cylindracea cholesterol esterase
D Ghosh, Z Wawrzak, VZ Pletnev, N Li, R Kaiser, W Pangborn, H Jörnvall, ...
Structure 3 (3), 279-288, 1995
1411995
Porcine carbonyl reductase: structural basis for a functional monomer in short chain dehydrogenases/reductases
D Ghosh, M Sawicki, V Pletnev, M Erman, S Ohno, S Nakajin, WL Duax
Journal of Biological Chemistry 276 (21), 18457-18463, 2001
1372001
Steroid dehydrogenase structures, mechanism of action, and disease
WL Duax, D Ghosh, V Pletnev
Academic Press 58, 121-148, 2000
1162000
X-ray structure of human aromatase reveals an androgen-specific active site
D Ghosh, J Griswold, M Erman, W Pangborn
The Journal of steroid biochemistry and molecular biology 118 (4-5), 197-202, 2010
1132010
A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa
AI den Hollander, TL McGee, C Ziviello, S Banfi, TP Dryja, ...
Investigative ophthalmology & visual science 50 (4), 1864-1872, 2009
1082009
Origin of substrate specificity of human and rat 17β-hydroxysteroid dehydrogenase type 1, using chimeric enzymes and site-directed substitutions
T Puranen, M Poutanen, D Ghosh, R Vihko, P Vihko
Endocrinology 138 (8), 3532-3539, 1997
1031997
Structural basis for the functional roles of critical residues in human cytochrome P450 aromatase
J Lo, G Di Nardo, J Griswold, C Egbuta, W Jiang, G Gilardi, D Ghosh
Biochemistry 52 (34), 5821-5829, 2013
942013
Characterization of structural and functional properties of human 17β-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis
T Puranen, M Poutanen, D Ghosh, P Vihko, R Vihko
Molecular endocrinology 11 (1), 77-86, 1997
921997
Recent progress in the discovery of next generation inhibitors of aromatase from the structure–function perspective
D Ghosh, J Lo, C Egbuta
Journal of medicinal chemistry 59 (11), 5131-5148, 2016
892016
The system can't perform the operation now. Try again later.
Articles 1–20