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Rada Savic
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Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions
RM Savic, MO Karlsson
The AAPS journal 11, 558-569, 2009
6352009
Diagnosing model diagnostics
MO Karlsson, RM Savic
Clinical Pharmacology & Therapeutics 82 (1), 17-20, 2007
5892007
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies
RM Savic, DM Jonker, T Kerbusch, MO Karlsson
Journal of pharmacokinetics and pharmacodynamics 34, 711-726, 2007
5672007
Tuberculous meningitis
RJ Wilkinson, U Rohlwink, UK Misra, R Van Crevel, NTH Mai, KE Dooley, ...
Nature reviews neurology 13 (10), 581-598, 2017
4432017
Four-month rifapentine regimens with or without moxifloxacin for tuberculosis
SE Dorman, P Nahid, EV Kurbatova, PPJ Phillips, K Bryant, KE Dooley, ...
New England Journal of Medicine 384 (18), 1705-1718, 2021
3352021
Model evaluation of continuous data pharmacometric models: metrics and graphics
THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ...
CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017
2942017
A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis
MZ Imperial, P Nahid, PPJ Phillips, GR Davies, K Fielding, D Hanna, ...
Nature medicine 24 (11), 1708-1715, 2018
2722018
Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study
JH Elliott, JH McMahon, CC Chang, SA Lee, W Hartogensis, N Bumpus, ...
The lancet HIV 2 (12), e520-e529, 2015
2562015
Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis
IH Bartelink, A Lalmohamed, EML van Reij, CC Dvorak, RM Savic, ...
The Lancet Haematology 3 (11), e526-e536, 2016
2262016
Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption
JJ Wilkins, RM Savic, MO Karlsson, G Langdon, H McIlleron, G Pillai, ...
Antimicrobial agents and chemotherapy 52 (6), 2138-2148, 2008
1942008
Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: a mechanistic model and tool for regimen and dose optimization
N Strydom, SV Gupta, WS Fox, LE Via, H Bang, M Lee, S Eum, TS Shim, ...
PLoS medicine 16 (4), e1002773, 2019
1572019
Optimizing hydroxychloroquine dosing for patients with COVID‐19: an integrative modeling approach for effective drug repurposing
M Garcia‐Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ...
Clinical Pharmacology & Therapeutics 108 (2), 253-263, 2020
1282020
GeneXpert MTB/Rif to diagnose tuberculous meningitis: perhaps the first test but not the last
NC Bahr, S Marais, M Caws, R Van Crevel, RJ Wilkinson, JS Tyagi, ...
Clinical Infectious Diseases 62 (9), 1133-1135, 2016
1272016
Designing drug trials: considerations for pregnant women
JS Sheffield, D Siegel, M Mirochnick, RP Heine, C Nguyen, KL Bergman, ...
Clinical infectious diseases 59 (suppl_7), S437-S444, 2014
1262014
Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial
SE Dorman, RM Savic, S Goldberg, JE Stout, N Schluger, G Muzanyi, ...
American journal of respiratory and critical care medicine 191 (3), 333-343, 2015
1252015
Importance of drug pharmacokinetics at the site of action
ML Rizk, L Zou, RM Savic, KE Dooley
Clinical and translational science 10 (3), 133, 2017
1082017
The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials
A Vernon, K Fielding, R Savic, L Dodd, P Nahid
PLoS medicine 16 (12), e1002884, 2019
922019
Population pharmacokinetics of busulfan in pediatric and young adult patients undergoing hematopoietic cell transplant: a model-based dosing algorithm for personalized therapy …
JR Long-Boyle, R Savic, S Yan, I Bartelink, L Musick, D French, J Law, ...
Therapeutic drug monitoring 37 (2), 236-245, 2015
892015
Effect of weight and maturation on busulfan clearance in infants and small children undergoing hematopoietic cell transplantation
RM Savic, MJ Cowan, CC Dvorak, SY Pai, L Pereira, IH Bartelink, ...
Biology of Blood and Marrow Transplantation 19 (11), 1608-1614, 2013
882013
Pharmacokinetics of desmopressin administrated as an oral lyophilisate dosage form in children with primary nocturnal enuresis and healthy adults
O Østerberg, RM Savic, MO Karlsson, USH Simonsson, JP Nørgaard, ...
The Journal of Clinical Pharmacology 46 (10), 1204-1211, 2006
832006
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