| Ru (II) compounds: next-generation anticancer metallotherapeutics? S Thota, DA Rodrigues, DC Crans, EJ Barreiro Journal of medicinal chemistry 61 (14), 5805-5821, 2018 | 400 | 2018 |
| N-Acylhydrazones as drugs S Thota, DA Rodrigues, PSM Pinheiro, LM Lima, CAM Fraga, EJ Barreiro Bioorganic & medicinal chemistry letters 28 (17), 2797-2806, 2018 | 169 | 2018 |
| Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors DA Rodrigues, GA Ferreira-Silva, ACS Ferreira, RA Fernandes, JK Kwee, ... Journal of medicinal chemistry 59 (2), 655-670, 2016 | 113 | 2016 |
| Duvelisib: a 2018 novel FDA-approved small molecule inhibiting phosphoinositide 3-kinases DA Rodrigues, FS Sagrillo, CAM Fraga Pharmaceuticals 12 (2), 69, 2019 | 60 | 2019 |
| Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities DA Rodrigues, PSM Pinheiro, FS Sagrillo, ML Bolognesi, CAM Fraga Medicinal research reviews 40 (6), 2177-2211, 2020 | 43 | 2020 |
| Synthesis, characterization, DNA binding, DNA cleavage, protein binding and cytotoxic activities of Ru (II) complexes S Thota, S Vallala, R Yerra, DA Rodrigues, NM Raghavendra, EJ Barreiro International journal of biological macromolecules 82, 663-670, 2016 | 42 | 2016 |
| Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors DA Rodrigues, FS Guerra, FS Sagrillo, P de Sena M. Pinheiro, MA Alves, ... ChemMedChem 15 (6), 539-551, 2020 | 34 | 2020 |
| The use of conformational restriction in medicinal chemistry P de Sena M Pinheiro, DA Rodrigues, R do Couto Maia, S Thota, ... Current topics in medicinal chemistry 19 (19), 1712-1733, 2019 | 30 | 2019 |
| Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and future prospects DA Rodrigues, PSM Pinheiro, CAM Fraga ChemMedChem 16 (3), 448-457, 2021 | 18 | 2021 |
| Beyond the selective inhibition of histone deacetylase 6 D A Rodrigues, S Thota, C AM Fraga Mini Reviews in Medicinal Chemistry 16 (14), 1175-1184, 2016 | 18 | 2016 |
| Theoretical and experimental characterization of 1, 4-N⋯ S σ-hole intramolecular interactions in bioactive N-acylhydrazone derivatives PSM Pinheiro, DA Rodrigues, MA Alves, LW Tinoco, GB Ferreira, ... New Journal of Chemistry 42 (1), 497-505, 2018 | 16 | 2018 |
| Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound TF Gomes, TET Pompeu, DA Rodrigues, F Noël, R Menegatti, ... European Journal of Medicinal Chemistry 62, 214-221, 2013 | 16 | 2013 |
| Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40) DA Rodrigues, PSM Pinheiro, TTSC Ferreira, S Thota, CAM Fraga Chemical Biology & Drug Design 91 (3), 668-680, 2018 | 15 | 2018 |
| Recent advances in development of polyphenols as anticancer agents S Thota, DA Rodrigues, EJ Barreiro Mini Reviews in Medicinal Chemistry 18 (15), 1265-1269, 2018 | 13 | 2018 |
| An unusual intramolecular halogen bond guides conformational selection R Tesch, C Becker, MP Müller, ME Beck, L Quambusch, M Getlik, ... Angewandte Chemie International Edition 57 (31), 9970-9975, 2018 | 13 | 2018 |
| The path to venetoclax resistance is paved with mutations, metabolism, and more GP Sullivan, L Flanagan, DA Rodrigues, T Ní Chonghaile Science Translational Medicine 14 (674), eabo6891, 2022 | 9 | 2022 |
| Advances in the Design and Development of PROTAC-mediated HDAC Degradation DA Rodrigues, A Roe, D Griffith, TN Chonghaile Current Topics in Medicinal Chemistry 22 (5), 408-424, 2022 | 9 | 2022 |
| Novel single inhibitor of HDAC6/8 and dual inhibitor of PI3K/HDAC6 as potential alternative treatments for prostate cancer FS Guerra, DA Rodrigues, CAM Fraga, PD Fernandes Pharmaceuticals 14 (5), 387, 2021 | 9 | 2021 |
| Modeling zinc‐oxygen coordination in histone deacetylase: a comparison of semiempirical methods performance PSM Pinheiro, DA Rodrigues, CMR Sant'Anna, CAM Fraga International Journal of Quantum Chemistry 118 (21), e25720, 2018 | 6 | 2018 |
| Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC H Zhang, CS Nabel, D Li, RÍ O’Connor, CR Crosby, SM Chang, Y Hao, ... Journal of Thoracic Oncology 18 (7), 882-895, 2023 | 3 | 2023 |
Carlos Alberto Manssour FragaProfessor de Farmacologia e Química Medicinal, Universidade Federal do Rio de JaneiroVerified email at ccsdecania.ufrj.br
