Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes JH Taube, JI Herschkowitz, K Komurov, AY Zhou, S Gupta, J Yang, ... Proceedings of the National Academy of Sciences 107 (35), 15449-15454, 2010 | 1202 | 2010 |
Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells YNV Gopal, W Deng, SE Woodman, K Komurov, P Ram, PD Smith, ... Cancer research 70 (21), 8736-8747, 2010 | 279 | 2010 |
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer HS Kim, S Mendiratta, J Kim, CV Pecot, JE Larsen, I Zubovych, BY Seo, ... Cell 155 (3), 552-566, 2013 | 193 | 2013 |
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma YNV Gopal, H Rizos, G Chen, W Deng, DT Frederick, ZA Cooper, ... Cancer research 74 (23), 7037-7047, 2014 | 191 | 2014 |
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies MA Smith, GS Choudhary, A Pellagatti, K Choi, LC Bolanos, TD Bhagat, ... Nature cell biology 21 (5), 640-650, 2019 | 187 | 2019 |
Revealing static and dynamic modular architecture of the eukaryotic protein interaction network K Komurov, M White Molecular systems biology 3 (1), 110, 2007 | 161 | 2007 |
The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells K Komurov, JT Tseng, M Muller, EG Seviour, TJ Moss, L Yang, D Nagrath, ... Molecular systems biology 8 (1), 596, 2012 | 128 | 2012 |
NetWalker: a contextual network analysis tool for functional genomics K Komurov, S Dursun, S Erdin, PT Ram BMC genomics 13, 1-9, 2012 | 122 | 2012 |
AMP kinase promotes glioblastoma bioenergetics and tumour growth RR Chhipa, Q Fan, J Anderson, R Muraleedharan, Y Huang, G Ciraolo, ... Nature cell biology 20 (7), 823-835, 2018 | 119 | 2018 |
Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data K Komurov, MA White, PT Ram PLoS computational biology 6 (8), e1000889, 2010 | 109 | 2010 |
Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia M Kesarwani, Z Kincaid, A Gomaa, E Huber, S Rohrabaugh, Z Siddiqui, ... Nature medicine 23 (4), 472-482, 2017 | 94 | 2017 |
A calcium-and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes J Fang, X Liu, L Bolanos, B Barker, C Rigolino, A Cortelezzi, EN Oliva, ... Nature medicine 22 (7), 727-734, 2016 | 78 | 2016 |
Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling Y Lu, M Muller, D Smith, B Dutta, K Komurov, S Iadevaia, D Ruths, ... Oncogene 30 (45), 4567-4577, 2011 | 70 | 2011 |
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network J Fang, B Barker, L Bolanos, X Liu, A Jerez, H Makishima, S Christie, ... Cell reports 8 (5), 1328-1338, 2014 | 68 | 2014 |
Biomarker accessible and chemically addressable mechanistic subtypes of BRAF melanoma B Eskiocak, EA McMillan, S Mendiratta, RK Kollipara, H Zhang, ... Cancer discovery 7 (8), 832-851, 2017 | 60 | 2017 |
IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival AK Adams, LC Bolanos, PJ Dexheimer, RA Karns, BJ Aronow, K Komurov, ... Oncotarget 6 (41), 43395, 2015 | 52 | 2015 |
Targeting SRC in mucinous ovarian carcinoma K Matsuo, M Nishimura, JN Bottsford-Miller, J Huang, K Komurov, ... Clinical cancer research 17 (16), 5367-5378, 2011 | 49 | 2011 |
An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system K Choi, K Komurov, JS Fletcher, E Jousma, JA Cancelas, J Wu, N Ratner Scientific Reports 7 (1), 43315, 2017 | 46 | 2017 |
Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling K Komurov, D Padron, T Cheng, M Roth, KP Rosenblatt, MA White Journal of biological chemistry 285 (27), 21134-21142, 2010 | 44 | 2010 |
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer N Oatman, N Dasgupta, P Arora, K Choi, MV Gawali, N Gupta, ... Science Advances 7 (7), eabd7459, 2021 | 42 | 2021 |