Frank Kirstein
Frank Kirstein
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Allergic airway disease is unaffected by the absence of IL-4Rα–dependent alternatively activated macrophages
NE Nieuwenhuizen, F Kirstein, J Jayakumar, B Emedi, R Hurdayal, ...
Journal of Allergy and Clinical Immunology 130 (3), 743-750. e8, 2012
Differential responses to natural and recombinant allergens in a murine model of fish allergy
ML van der Ventel, NE Nieuwenhuizen, F Kirstein, C Hikuam, ...
Molecular immunology 48 (4), 637-646, 2011
B cells that produce immunoglobulin E mediate colitis in BALB/c mice
JC Hoving, F Kirstein, NE Nieuwenhuizen, LCE Fick, E Hobeika, M Reth, ...
Gastroenterology 142 (1), 96-108, 2012
The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection
M Darby, C Schnoeller, A Vira, F Culley, S Bobat, E Logan, F Kirstein, ...
PLoS pathogens 11 (1), e1004636, 2015
Microbial ligand costimulation drives neutrophilic steroid-refractory asthma
S Hadebe, F Kirstein, K Fierens, K Chen, RA Drummond, S Vautier, ...
PLoS One 10 (8), e0134219, 2015
IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection
WGC Horsnell, MG Darby, JC Hoving, N Nieuwenhuizen, HJ McSorley, ...
PLoS pathogens 9 (10), e1003662, 2013
IL-4Rα-responsive smooth muscle cells contribute to initiation of TH2 immunity and pulmonary pathology in Nippostrongylus brasiliensis infections
WGC Horsnell, A Vira, F Kirstein, H Mearns, JC Hoving, AJ Cutler, ...
Mucosal immunology 4 (1), 83-92, 2011
Expression of IL-4 receptor α on smooth muscle cells is not necessary for development of experimental allergic asthma
F Kirstein, WGC Horsnell, DA Kuperman, X Huang, DJ Erle, AL Lopata, ...
Journal of Allergy and Clinical Immunology 126 (2), 347-354, 2010
Interleukin-4-Promoted T Helper 2 Responses Enhance Nippostrongylus brasiliensis-Induced Pulmonary Pathology
H Mearns, WGC Horsnell, JC Hoving, B Dewals, AJ Cutler, F Kirstein, ...
Infection and immunity 76 (12), 5535-5542, 2008
β-Glucan exacerbates allergic airway responses to house dust mite allergen
S Hadebe, F Kirstein, K Fierens, P Redelinghuys, GI Murray, DL Williams, ...
Respiratory research 17, 1-3, 2016
Role of IL-4 receptor α–positive CD4+ T cells in chronic airway hyperresponsiveness
F Kirstein, NE Nieuwenhuizen, J Jayakumar, WGC Horsnell, ...
Journal of Allergy and Clinical Immunology 137 (6), 1852-1862. e9, 2016
Anisakis pegreffii-Induced Airway Hyperresponsiveness Is Mediated by Gamma Interferon in the Absence of Interleukin-4 Receptor Alpha Responsiveness
F Kirstein, WGC Horsnell, N Nieuwenhuizen, B Ryffel, AL Lopata, ...
Infection and Immunity 78 (9), 4077-4086, 2010
Investigation of in vitro and in vivo anti-asthmatic properties of Siphonochilus aethiopicus
G Fouche, N Nieuwenhuizen, V Maharaj, S van Rooyen, N Harding, ...
Journal of ethnopharmacology 133 (2), 843-849, 2011
Occupational allergy to latex among loom tuners in a textile factory
AL Lopata, S Adams, F Kirstein, N Henwood, M Raulf-Heimsoth, ...
International archives of allergy and immunology 144 (1), 64-68, 2007
IL-4Rα signaling in CD4+ CD25+ FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33
J Khumalo, F Kirstein, S Hadebe, F Brombacher
JCI insight 5 (20), 2020
Therapeutic and prophylactic deletion of IL‐4Ra‐signaling ameliorates established ovalbumin induced allergic asthma
J Khumalo, F Kirstein, M Scibiorek, S Hadebe, F Brombacher
Allergy 75 (6), 1347-1360, 2020
House dust mite induced allergic airway disease is attenuated in CD11ccreIL-4Rα−/l°x mice
NE Nieuwenhuizen, F Kirstein, JC Hoving, F Brombacher
Scientific reports 8 (1), 885, 2018
Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease
T Gogishvili, F Lühder, F Kirstein, NE Nieuwenhuizen, S Goebbels, ...
Journal of allergy and clinical immunology 130 (6), 1394-1403. e4, 2012
Deletion of IL-4Rα signaling on B cells limits hyperresponsiveness depending on antigen load
S Hadebe, J Khumalo, S Mangali, N Mthembu, H Ndlovu, M Scibiorek, ...
Journal of Allergy and Clinical Immunology 148 (1), 99-109. e5, 2021
Associations between environmental dust composition and atopic dermatitis in urban and rural settings
T Trikamjee, W Basera, M Botha, HE Facey‐Thomas, B Gaunt, J Genuneit, ...
Pediatric Allergy and Immunology 32 (5), 1013-1021, 2021
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