Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells RI Benhamou, M Bibi, KB Steinbuch, H Engel, M Levin, Y Roichman, ... ACS Chemical Biology, 2017 | 68 | 2017 |
Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model GK Viswanathan, D Shwartz, Y Losev, E Arad, C Shemesh, E Pichinuk, ... Cellular and Molecular Life Sciences 77, 2795-2813, 2020 | 55 | 2020 |
Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation D Laor, D Sade, S Shaham-Niv, D Zaguri, M Gartner, V Basavalingappa, ... Nature communications 10 (1), 62, 2019 | 54 | 2019 |
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models J Ganz, T Shacham, M Kramer, M Shenkman, H Eiger, N Weinberg, ... Scientific Reports 10 (1), 6875, 2020 | 43 | 2020 |
Path-Integral Calculations of Nuclear Quantum Effects in Model Systems, Small Molecules, and Enzymes via Gradient-Based Forward Corrector Algorithms A Azuri, H Engel, D Doron, DT Major Journal of Chemical Theory and Computation 7 (5), 1273-1286, 2011 | 41 | 2011 |
Classical and Quantum Modeling of Li and Na Diffusion in FePO4 M Dixit, H Engel, R Eitan, D Aurbach, MD Levi, M Kosa, DT Major The Journal of Physical Chemistry C 119 (28), 15801-15809, 2015 | 35 | 2015 |
Integrating in vitro and in silico approaches to evaluate the “dual functionality” of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils E Haj, Y Losev, VG KrishnaKumar, E Pichinuk, H Engel, A Raveh, E Gazit, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (7), 1565-1575, 2018 | 33 | 2018 |
Hybrid quantum and classical simulations of the formate dehydrogenase catalyzed hydride transfer reaction on an accurate semiempirical potential energy surface A Vardi-Kilshtain, DT Major, A Kohen, H Engel, D Doron Journal of Chemical Theory and Computation 8 (11), 4786-4796, 2012 | 33 | 2012 |
Momentum distribution as a fingerprint of quantum delocalization in enzymatic reactions: open-chain path-integral simulations of model systems and the hydride transfer in … H Engel, D Doron, A Kohen, DT Major Journal of Chemical Theory and Computation 8 (4), 1223-1234, 2012 | 31 | 2012 |
Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex ML Bar-El, P Vaňková, A Yeheskel, L Simhaev, H Engel, P Man, Y Haitin, ... Nature Communications 11 (1), 5273, 2020 | 26 | 2020 |
Chemical Modifications Reduce Auditory Cell Damage Induced by Aminoglycoside Antibiotics SL Zada, BB Baruch, L Simhaev, H Engel, M Fridman Journal of the American Chemical Society 142 (6), 3077-3087, 2020 | 23 | 2020 |
Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone‐Dopamine hybrid A Paul, GKK Viswanathan, A Huber, E Arad, H Engel, R Jelinek, E Gazit, ... The FEBS Journal, 2021 | 17 | 2021 |
Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism O Kakhlon, H Vaknin, K Mishra, J D’Souza, M Marisat, U Sprecher, ... EMBO molecular medicine 13 (10), e14554, 2021 | 14 | 2021 |
Chemical Chaperones Modulate the Formation of Metabolite Assemblies H Adsi, SA Levkovich, E Haimov, T Kreiser, M Meli, H Engel, L Simhaev, ... International Journal of Molecular Sciences 22 (17), 9172, 2021 | 7 | 2021 |
Nuclear quantum effects in chemical reactions via higher-order path-integral calculations H Engel, R Eitan, A Azuri, DT Major Chemical Physics 450, 95-101, 2015 | 7 | 2015 |
Multiscale Quantum‐Classical Simulations of Enzymes D Doron, M Weitman, A Vardi‐Kilshtain, A Azuri, H Engel, DT Major Israel Journal of Chemistry 54 (8‐9), 1108-1117, 2014 | 7 | 2014 |
Global uniform semiclassical approximation for Clebsch-Gordan coefficients H Engel, KG Kay The Journal of chemical physics 128 (9), 094104, 2008 | 7 | 2008 |
Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment S Burg, S Shapiro, A Peretz, E Haimov, B Redko, A Yeheskel, L Simhaev, ... Proceedings of the National Academy of Sciences 119 (34), e2202926119, 2022 | 6 | 2022 |
Mechanisms of metabolite amyloid formation: computational studies for drug design against metabolic disorders M Meli, H Engel, D Laor, E Gazit, G Colombo ACS medicinal chemistry letters 10 (4), 666-670, 2019 | 6 | 2019 |
Inhibition of amyloid fibrillation of γD-crystallin model peptide by the cochineal Carmine M Abu-Hussien, GK Viswanathan, L Borisover, M Mimouni, H Engel, ... International Journal of Biological Macromolecules 169, 342-351, 2021 | 5 | 2021 |