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Hamutal Engel
Hamutal Engel
PhD - Computational Chemistry
Verified email at post.tau.ac.il
Title
Cited by
Cited by
Year
Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells
RI Benhamou, M Bibi, KB Steinbuch, H Engel, M Levin, Y Roichman, ...
ACS Chemical Biology, 2017
682017
Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model
GK Viswanathan, D Shwartz, Y Losev, E Arad, C Shemesh, E Pichinuk, ...
Cellular and Molecular Life Sciences 77, 2795-2813, 2020
552020
Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation
D Laor, D Sade, S Shaham-Niv, D Zaguri, M Gartner, V Basavalingappa, ...
Nature communications 10 (1), 62, 2019
542019
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models
J Ganz, T Shacham, M Kramer, M Shenkman, H Eiger, N Weinberg, ...
Scientific Reports 10 (1), 6875, 2020
432020
Path-Integral Calculations of Nuclear Quantum Effects in Model Systems, Small Molecules, and Enzymes via Gradient-Based Forward Corrector Algorithms
A Azuri, H Engel, D Doron, DT Major
Journal of Chemical Theory and Computation 7 (5), 1273-1286, 2011
412011
Classical and Quantum Modeling of Li and Na Diffusion in FePO4
M Dixit, H Engel, R Eitan, D Aurbach, MD Levi, M Kosa, DT Major
The Journal of Physical Chemistry C 119 (28), 15801-15809, 2015
352015
Integrating in vitro and in silico approaches to evaluate the “dual functionality” of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils
E Haj, Y Losev, VG KrishnaKumar, E Pichinuk, H Engel, A Raveh, E Gazit, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (7), 1565-1575, 2018
332018
Hybrid quantum and classical simulations of the formate dehydrogenase catalyzed hydride transfer reaction on an accurate semiempirical potential energy surface
A Vardi-Kilshtain, DT Major, A Kohen, H Engel, D Doron
Journal of Chemical Theory and Computation 8 (11), 4786-4796, 2012
332012
Momentum distribution as a fingerprint of quantum delocalization in enzymatic reactions: open-chain path-integral simulations of model systems and the hydride transfer in …
H Engel, D Doron, A Kohen, DT Major
Journal of Chemical Theory and Computation 8 (4), 1223-1234, 2012
312012
Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex
ML Bar-El, P Vaňková, A Yeheskel, L Simhaev, H Engel, P Man, Y Haitin, ...
Nature Communications 11 (1), 5273, 2020
262020
Chemical Modifications Reduce Auditory Cell Damage Induced by Aminoglycoside Antibiotics
SL Zada, BB Baruch, L Simhaev, H Engel, M Fridman
Journal of the American Chemical Society 142 (6), 3077-3087, 2020
232020
Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone‐Dopamine hybrid
A Paul, GKK Viswanathan, A Huber, E Arad, H Engel, R Jelinek, E Gazit, ...
The FEBS Journal, 2021
172021
Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism
O Kakhlon, H Vaknin, K Mishra, J D’Souza, M Marisat, U Sprecher, ...
EMBO molecular medicine 13 (10), e14554, 2021
142021
Chemical Chaperones Modulate the Formation of Metabolite Assemblies
H Adsi, SA Levkovich, E Haimov, T Kreiser, M Meli, H Engel, L Simhaev, ...
International Journal of Molecular Sciences 22 (17), 9172, 2021
72021
Nuclear quantum effects in chemical reactions via higher-order path-integral calculations
H Engel, R Eitan, A Azuri, DT Major
Chemical Physics 450, 95-101, 2015
72015
Multiscale Quantum‐Classical Simulations of Enzymes
D Doron, M Weitman, A Vardi‐Kilshtain, A Azuri, H Engel, DT Major
Israel Journal of Chemistry 54 (8‐9), 1108-1117, 2014
72014
Global uniform semiclassical approximation for Clebsch-Gordan coefficients
H Engel, KG Kay
The Journal of chemical physics 128 (9), 094104, 2008
72008
Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment
S Burg, S Shapiro, A Peretz, E Haimov, B Redko, A Yeheskel, L Simhaev, ...
Proceedings of the National Academy of Sciences 119 (34), e2202926119, 2022
62022
Mechanisms of metabolite amyloid formation: computational studies for drug design against metabolic disorders
M Meli, H Engel, D Laor, E Gazit, G Colombo
ACS medicinal chemistry letters 10 (4), 666-670, 2019
62019
Inhibition of amyloid fibrillation of γD-crystallin model peptide by the cochineal Carmine
M Abu-Hussien, GK Viswanathan, L Borisover, M Mimouni, H Engel, ...
International Journal of Biological Macromolecules 169, 342-351, 2021
52021
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