Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 8736 | 2021 |
Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection L Townsend, AH Dyer, K Jones, J Dunne, A Mooney, F Gaffney, ... PloS one 15 (11), e0240784, 2020 | 428 | 2020 |
Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7 L Unterholzner, RP Sumner, M Baran, H Ren, DS Mansur, NM Bourke, ... PLoS pathogens 7 (9), e1002247, 2011 | 162 | 2011 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 140 | 2021 |
Persistent poor health after COVID-19 is not associated with respiratory complications or initial disease severity L Townsend, J Dowds, K O’Brien, G Sheill, AH Dyer, B O’Kelly, JP Hynes, ... Annals of the American Thoracic Society 18 (6), 997-1003, 2021 | 135 | 2021 |
Prolonged elevation of D‐dimer levels in convalescent COVID‐19 patients is independent of the acute phase response L Townsend, H Fogarty, A Dyer, I Martin‐Loeches, C Bannan, ... Journal of thrombosis and haemostasis 19 (4), 1064-1070, 2021 | 77 | 2021 |
Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV NJ Stevenson, AG Murphy, NM Bourke, CA Keogh, JE Hegarty, ... PloS one 6 (11), e27866, 2011 | 54 | 2011 |
Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes NJ Stevenson, NM Bourke, EJ Ryan, M Binder, L Fanning, JA Johnston, ... FEBS letters 587 (10), 1571-1578, 2013 | 51 | 2013 |
A novel anti-viral role for STAT3 in IFN-α signalling responses R Mahony, S Gargan, KL Roberts, N Bourke, SE Keating, AG Bowie, ... Cellular and Molecular Life Sciences 74 (9), 1755-1764, 2017 | 35 | 2017 |
Epigenetic clocks and allostatic load reveal potential sex-specific drivers of biological aging C McCrory, G Fiorito, S McLoughlin, S Polidoro, CN Cheallaigh, N Bourke, ... The Journals of Gerontology: Series A 75 (3), 495-503, 2020 | 24 | 2020 |
A comparative analysis of the status anxiety hypothesis of socio-economic inequalities in health based on 18,349 individuals in four countries and five cohort studies R Layte, C McCrory, CN Cheallaigh, N Bourke, M Kivimaki, AI Ribeiro, ... Scientific reports 9 (1), 1-12, 2019 | 23 | 2019 |
A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling NA de Weerd, AY Matthews, PR Pattie, NM Bourke, SS Lim, JP Vivian, ... Journal of Biological Chemistry 292 (18), 7554-7565, 2017 | 21 | 2017 |
Longitudinal analysis of COVID-19 patients shows age-associated T cell changes independent of ongoing ill-health L Townsend, AH Dyer, A Naughton, R Kiersey, D Holden, M Gardiner, ... Frontiers in immunology, 1593, 2021 | 17 | 2021 |
Control of HIV infection by IFN-α: implications for latency and a cure NM Bourke, S Napoletano, C Bannan, S Ahmed, C Bergin, Á McKnight, ... Cellular and Molecular Life Sciences 75 (5), 775-783, 2018 | 15 | 2018 |
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation JK Dowling, CE Becker, NM Bourke, SC Corr, DJ Connolly, SR Quinn, ... Journal of Biological Chemistry 289 (10), 6429-6437, 2014 | 15 | 2014 |
Properties and functions of the novel type I interferon epsilon ZRC Marks, N Campbell, NA deWeerd, SS Lim, LJ Gearing, NM Bourke, ... Seminars in Immunology 43, 101328, 2019 | 14 | 2019 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Taylor and Francis Ltd. 17 (1), 1-382, 2021 | 13 | 2021 |
Type I IFNs in the female reproductive tract: The first line of defense in an ever‐changing battleground HE Cumming, NM Bourke Journal of leukocyte biology 105 (2), 353-361, 2019 | 10 | 2019 |
Investigating the relationship between vitamin D and persistent symptoms following SARS-CoV-2 infection L Townsend, AH Dyer, P McCluskey, K O’Brien, J Dowds, E Laird, ... Nutrients 13 (7), 2430, 2021 | 9 | 2021 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 6 | 2022 |