| Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody RNN Abskharon, G Giachin, A Wohlkonig, SH Soror, E Pardon, ... Journal of the American Chemical Society 136 (3), 937-944, 2014 | 131 | 2014 |
| Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1, 2, 4-oxadiazole EthR inhibitors M Flipo, M Desroses, N Lecat-Guillet, B Villemagne, N Blondiaux, ... Journal of medicinal chemistry 55 (1), 68-83, 2012 | 93 | 2012 |
| A llama-derived gelsolin single-domain antibody blocks gelsolin–G-actin interaction A Van den Abbeele, S De Clercq, A De Ganck, V De Corte, B Van Loo, ... Cellular and molecular life sciences 67, 1519-1535, 2010 | 78 | 2010 |
| Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking … B Villemagne, M Flipo, N Blondiaux, C Crauste, S Malaquin, F Leroux, ... Journal of medicinal chemistry 57 (11), 4876-4888, 2014 | 73 | 2014 |
| Histone H3K27M mutation overrides histological grading in pediatric gliomas A Mosaab, M El-Ayadi, EN Khorshed, N Amer, A Refaat, M El-Beltagy, ... Scientific reports 10 (1), 8368, 2020 | 58 | 2020 |
| Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors A Joncour, N Desroy, C Housseman, X Bock, N Bienvenu, L Cherel, ... Journal of Medicinal Chemistry 60 (17), 7371-7392, 2017 | 54 | 2017 |
| Elevated expression of MiR-17 in microglia of Alzheimer’s disease patients abrogates autophagy-mediated amyloid-β degradation S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, ... Frontiers in immunology 12, 705581, 2021 | 40 | 2021 |
| Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands X Carette, N Blondiaux, E Willery, S Hoos, N Lecat-Guillet, Z Lens, ... Nucleic acids research 40 (7), 3018-3030, 2012 | 40 | 2012 |
| Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors MS Mohamed, AI Sayed, MA Khedr, SH Soror Bioorganic & medicinal chemistry 24 (9), 2146-2157, 2016 | 33 | 2016 |
| A cold-active esterase of Streptomyces coelicolor A3(2): from genome sequence to enzyme activity SH Soror, V Verma, R Rao, S Rasool, S Koul, GN Qazi, J Cullum Journal of Industrial Microbiology and Biotechnology 34 (8), 525-531, 2007 | 32 | 2007 |
| Novel antiviral compounds against gastroenteric viral infections MS Mohamed, RH Abd El‐Hameed, AI Sayed, SH Soror Archiv der Pharmazie 348 (3), 194-205, 2015 | 31 | 2015 |
| Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, ... Scientific reports 11 (1), 855, 2021 | 30 | 2021 |
| Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion R Abskharon, F Wang, A Wohlkonig, J Ruan, S Soror, G Giachin, ... PLoS Pathogens 15 (12), e1008139, 2019 | 29 | 2019 |
| Role of Diosmin in protection against the oxidative stress induced damage by gamma-radiation in Wistar albino rats S Mahgoub, AO Sallam, HKA Sarhan, AAA Ammar, SH Soror Regulatory Toxicology and Pharmacology 113, 104622, 2020 | 28 | 2020 |
| A novel expression system for production of soluble prion proteins in E. coli RNN Abskharon, S Ramboarina, H El Hassan, W Gad, MI Apostol, ... Microbial Cell Factories 11, 1-11, 2012 | 28 | 2012 |
| Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes RNN Abskharon, SH Soror, E Pardon, H El Hassan, G Legname, ... Protein engineering, design & selection 24 (9), 737-741, 2011 | 23 | 2011 |
| Inflammasome genes’ polymorphisms in Egyptian chronic hepatitis C patients: influence on vulnerability to infection and response to treatment SZK Estfanous, SA Ali, SM Seif, SHA Soror, DHA Abdelaziz Mediators of inflammation 2019, 2019 | 22 | 2019 |
| Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces … SH Soror, R Rao, J Cullum Protein Engineering, Design & Selection 22 (6), 333-339, 2009 | 22 | 2009 |
| Expression, Purification, Characterization, and Solution Nuclear Magnetic Resonance Study of Highly Deuterated Yeast Cytochrome c Peroxidase with Enhanced … AN Volkov, A Wohlkonig, SH Soror, NAJ Van Nuland Biochemistry 52 (13), 2165-2175, 2013 | 20 | 2013 |
| High-resolution structure of a papaya plant-defence barwin-like protein solved by in-house sulfur-SAD phasing J Huet, EJ Teinkela Mbosso, S Soror, F Meyer, Y Looze, R Wintjens, ... Acta Crystallographica Section D: Biological Crystallography 69 (10), 2017-2026, 2013 | 19 | 2013 |
Alexandre WohlkonigStaff ScientistVerified email at vub.be
