|Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects|
FZ Stanczyk, JP Hapgood, S Winer, DR Mishell Jr
Endocrine reviews 34 (2), 171-208, 2013
|A fully dissociated compound of plant origin for inflammatory gene repression|
K De Bosscher, WV Berghe, IME Beck, W Van Molle, N Hennuyer, ...
Proceedings of the National Academy of Sciences 102 (44), 15827-15832, 2005
|Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception|
D Africander, N Verhoog, JP Hapgood
Steroids 76 (7), 636-652, 2011
|Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus)|
N Illing, BE Troskie, CS Nahorniak, JP Hapgood, RE Peter, RP Millar
Proceedings of the National Academy of Sciences 96 (5), 2526-2531, 1999
|Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction|
K Ronacher, K Hadley, C Avenant, E Stubsrud, SS Simons Jr, A Louw, ...
Molecular and cellular endocrinology 299 (2), 219-231, 2009
|Synthetic progestins used in HRT have different glucocorticoid agonist properties|
D Koubovec, K Ronacher, E Stubsrud, A Louw, JP Hapgood
Molecular and cellular endocrinology 242 (1-2), 23-32, 2005
|Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity.|
J Hapgood, S Cuthill, M Denis, L Poellinger, JA Gustafsson
Proceedings of the National Academy of Sciences 86 (1), 60-64, 1989
|Regulation of expression of mammalian gonadotrophin‐releasing hormone receptor genes|
JP Hapgood, H Sadie, W Van Biljon, K Ronacher
Journal of neuroendocrinology 17 (10), 619-638, 2005
|Identification of three putative GnRH receptor subtypes in vertebrates|
B Troskie, N Illing, E Rumbak, YM Sun, J Hapgood, S Sealfon, D Conklin, ...
General and comparative endocrinology 112 (3), 296-302, 1998
|Potency of progestogens used in hormonal therapy: toward understanding differential actions|
JP Hapgood, D Africander, R Louw, RM Ray, JM Rohwer
The Journal of steroid biochemistry and molecular biology 142, 39-47, 2014
|Hormonal contraception and HIV-1 acquisition: biological mechanisms|
JP Hapgood, C Kaushic, Z Hel
Endocrine reviews 39 (1), 36-78, 2018
|Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a|
S Robertson, F Allie-Reid, WV Berghe, K Visser, A Binder, D Africander, ...
Journal of Biological Chemistry 285 (11), 8061-8075, 2010
|Complementary deoxyribonucleic acid cloning, gene expression, and ligand selectivity of a novel gonadotropin-releasing hormone receptor expressed in the pituitary and midbrain …|
BE Troskie, JP Hapgood, RP Millar, N Illing
Endocrinology 141 (5), 1764-1771, 2000
|A novel human GnRH receptor homolog gene: abundant and wide tissue distribution of the antisense transcript|
R Millar, D Conklin, C Lofton-Day, E Hutchinson, B Troskie, N Illing, ...
Journal of Endocrinology 162 (1), 117-126, 1999
|A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists: identification of D-Lys6 in the ligand and extracellular loop two of …|
YM Sun, CA Flanagan, N Illing, TR Ott, R Sellar, BJ Fromme, J Hapgood, ...
Journal of Biological Chemistry 276 (11), 7754-7761, 2001
|Depot medroxyprogesterone versus norethisterone oenanthate for long-acting progestogenic contraception|
BH Draper, C Morroni, M Hoffman, J Smit, M Beksinska, J Hapgood, ...
The Cochrane database of systematic reviews., CD005214, 2006
|Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity|
C Avenant, K Ronacher, E Stubsrud, A Louw, JP Hapgood
Molecular and cellular endocrinology 327 (1-2), 72-88, 2010
|The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the …|
Y Govender, C Avenant, NJD Verhoog, RM Ray, NJ Grantham, ...
PloS one 9 (5), e96497, 2014
|Not all progestins are the same: implications for usage|
JP Hapgood, D Koubovec, A Louw, D Africander
Trends in pharmacological sciences 25 (11), 554-557, 2004
|REGULATION OF GENE EXPRESSION BY GC‐RICH DNA CIS ‐ELEMENTS|
JP Hapgood, J Riedemann, SD Scherer
Cell biology international 25 (1), 17-31, 2001